Effects of Metoprolol Combined with Experiential Multilevel Cooperative Exercise Rehabilitation on Short-Term Prognosis in Patients with Coronary Heart Disease

Yi CHEN; Cheng REN; Jiaxian SONG; Xin HE; Li WANG; Jinyan HUANG; Jingyu SUN

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Yi CHEN, Cheng REN, Jiaxian SONG, Xin HE, Li WANG, Jinyan HUANG, Jingyu SUN. Effects of Metoprolol Combined with Experiential Multilevel Cooperative Exercise Rehabilitation on Short-Term Prognosis in Patients with Coronary Heart Disease[J]. Journal of Kunming Medical University.

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Effects of Metoprolol Combined with Experiential Multilevel Cooperative Exercise Rehabilitation on Short-Term Prognosis in Patients with Coronary Heart Disease

Department of Cardiology，The First People’s Hospital of Zhangjiagang City，Jiangsu Zhangjiagang 215600，China

Received Date: 2025-11-25

Abstract

Abstract

Objective To investigate the effects of metoprolol combined with experiential, multi-level interventions and exercise rehabilitation training on the short-term prognosis in patients with coronary heart disease. Methods A total of 90 CHD patients admitted to the Department of Cardiovascular Medicine, Zhangjiagang First People’s Hospital between January 2023 and December 2024 were selected as study subjects. They were divided according to different treatment regimens into a control group of 45 patients （receiving conventional intervention） and a study group of 45 patients （receiving metoprolol combined with an experiential, multi-level intervention model and exercise rehabilitation training. The two groups were compared in terms of echocardiographic and cardiopulmonary function parameters, ventricular remodeling, quality of life, clinical efficacy, and the incidence of adverse reactions. Results Intervention in, Following treatment, Compared with the control group, the study group demonstrated reductions in NT-proBNP, CK-MB, cTnI, LVESV, LVEDV, LVPWT, LVMI, MLHFQ scores, total incidence of adverse reactions, and MACE incidence during and after intervention （P<0.05）, while cardiac function, FVC, FEV1, VCmax, AT, METs, Peak VO2, WR, SF-36 scores, and overall response rate increased significantly （P < 0.05）. Conclusion The combination of metoprolol with the experiential multi-level intervention model and exercise rehabilitation training demonstrates significant therapeutic efficacy, enhancing patients' cardiopulmonary function and ventricular remodeling, reducing adverse reactions, and improving short-term prognosis in CHD patients.
- Metoprolol,
- Experiential multi-level intervention model,
- Exercise rehabilitation training,
- Coronary heart disease

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References(25)

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