Citation: | Yichao JIN, Xiaochuan WANG, Chunping AO, Liangheng XU. Pruritus in Keloid:Pathogenesis and Treatments[J]. Journal of Kunming Medical University. |
[1] |
Jeschke M G,Wood F M,Middelkoop E,et al. Scars[J]. Nature Reviews Disease Primers,2023,9(1):1-16. doi: 10.1038/s41572-022-00413-2
|
[2] |
Bijlard E,Kouwenberg C A E,Timman R,et al. Burden of Keloid Disease: A cross-sectional health-related quality of life assessment[J]. Acta Derm Venereol,2017,97(2):225-229. doi: 10.2340/00015555-2498
|
[3] |
Kassi K,Kouame K,Kouassi A,et al. Quality of life in black African patients with keloid scars[J]. Dermatology Reports,2020,12(2):28-31.
|
[4] |
Jumper N,Paus R,Bayat A. Functional histopathology of keloid disease[J]. Histol Histopathol,2015,30(2):1033-1057.
|
[5] |
Yin S-L,Qin Z-L,Yang X. Role of periostin in skin wound healing and pathologic scar formation[J]. Chinese Medical Journal,2020,133(18):2236-2238. doi: 10.1097/CM9.0000000000000949
|
[6] |
Hashimoto T,Mishra SK,Olivry T,Yosipovitch G. Periostin,an emerging player in itch sensation[J]. J Invest Dermatol,2021,141(10):2338-2343. doi: 10.1016/j.jid.2021.03.009
|
[7] |
Bagabir R,Byers R J,Chaudhry I H,et al. Site-specific immunophenotyping of keloid disease demonstrates immune upregulation and the presence of lymphoid aggregates[J]. The British Journal of Dermatology,2012,167(5):1053-1066. doi: 10.1111/j.1365-2133.2012.11190.x
|
[8] |
Wang N,Liang H,Zen K. Molecular mechanisms that influence the macrophage m1-m2 polarization balance[J]. Frontiers in Immunology,2014,5(1):1-9.
|
[9] |
Wu J,Del Duca E,Espino M,et al. RNA Sequencing Keloid Transcriptome Associates Keloids With Th2,Th1,Th17/Th22,and JAK3-Skewing[J]. Frontiers in Immunology,2020,11(1):177-180. doi: 10.3389/fimmu.2020.00177
|
[10] |
Garcovich S,Maurelli M,Gisondi P,et al. Pruritus as a Distinctive Feature of Type 2 Inflammation[J]. Vaccines (Basel),2021,9(3):1-16.
|
[11] |
Xu J,Zanvit P,Hu L,et al. The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching[J]. Immunity,2020,53(2):371-383. doi: 10.1016/j.immuni.2020.06.023
|
[12] |
Datsi A,Steinhoff M,Ahmad F,et al. Interleukin-31: The “itchy” cytokine in inflammation and therapy[J]. Allergy,2021,76(10):2982-2997.
|
[13] |
Wilgus T A,Wulff B C. The Importance of Mast Cells in Dermal Scarring[J]. Adv Wound Care (New Rochelle),2014,3(4):356-365.
|
[14] |
Lee S S,Yosipovitch G,Chan Y H,et al. Pruritus,pain,and small nerve fiber function in keloids: A controlled study[J]. Journal of the American Academy of Dermatology,2004,51(6):1002-1006.
|
[15] |
Tey H L,Maddison B,Wang H,et al. Cutaneous innervation and itch in keloids[J]. Acta Dermato-Venereologica,2012,92(5):529-531. doi: 10.2340/00015555-1336
|
[16] |
Leal E C,Carvalho E,Tellechea A,et al. Substance P promotes wound healing in diabetes by modulating inflammation and macrophage phenotype[J]. The American Journal of Pathology,2015,185(6):1638-1648. doi: 10.1016/j.ajpath.2015.02.011
|
[17] |
Chen W,Fu X,Sun X,et al. Analysis of differentially expressed genes in keloids and normal skin with cDNA microarray[J]. The Journal of Surgical Research,2003,113(2):208-216. doi: 10.1016/S0022-4804(03)00188-4
|
[18] |
Tomioka M,Stead R H,Nielsen L,et al. Nerve growth factor enhances antigen and other secretagogue-induced histamine release from rat peritoneal mast cells in the absence of phosphatidylserine[J]. The Journal of Allergy and Clinical Immunology,1988,82(4):599-607. doi: 10.1016/0091-6749(88)90971-2
|
[19] |
Kanda N,Watanabe S. Histamine enhances the production of nerve growth factor in human keratinocytes[J]. The Journal of Investigative Dermatology,2003,121(3):570-577. doi: 10.1046/j.1523-1747.2003.12428.x
|
[20] |
Mustoe T A,Cooter R D,Gold M H,et al. International clinical recommendations on scar management[J]. Plastic and Reconstructive Surgery,2002,110(2):560-571. doi: 10.1097/00006534-200208000-00031
|
[21] |
Morelli Coppola M,Salzillo R,Segreto F,et al. Triamcinolone acetonide intralesional injection for the treatment of keloid scars: patient selection and perspectives[J]. Clinical,Cosmetic and Investigational Dermatology,2018,111:387-396. doi: 10.2147/CCID.S133672
|
[22] |
Cedeno-Laurent F,Singer E M,Wysocka M,et al. Improved pruritus correlates with lower levels of IL-31 in CTCL patients under different therapeutic modalities[J]. Clinical immunology (Orlando,Fla. ),2015,158(1):1-7. doi: 10.1016/j.clim.2015.02.014
|
[23] |
Yaseen B,Lopez H,Taki Z,et al. Interleukin-31 promotes pathogenic mechanisms underlying skin and lung fibrosis in scleroderma[J]. Rheumatology (Oxford,England),2020,59(9):2625-2636. doi: 10.1093/rheumatology/keaa195
|
[24] |
Hashimoto T,Nattkemper L A,Kim H S,et al. Itch intensity in prurigo nodularis is closely related to dermal interleukin-31,oncostatin M,IL-31 receptor alpha and oncostatin M receptor beta[J]. Experimental Dermatology,2021,30(6):804-810. doi: 10.1111/exd.14279
|
[25] |
Brunner P M,Khattri S,Garcet S,et al. A mild topical steroid leads to progressive anti-inflammatory effects in the skin of patients with moderate-to-severe atopic dermatitis[J]. The Journal of Allergy and Clinical Immunology,2016,138(1):169-178. doi: 10.1016/j.jaci.2015.12.1323
|
[26] |
Fowler E,Yosipovitch G. Chronic itch management: therapies beyond those targeting the immune system[J]. Annals of Allergy,Asthma & Immunology,Elsevier,2019,123(2): 158-165.
|
[27] |
李峥,张兵,李巍,等. 加巴喷丁治疗深Ⅱ度烧伤后瘢痕瘙痒的临床效果[J]. 中华烧伤杂志,2015,31(3):177-180.
|
[28] |
Lee H G,Grossman S K,Valdes-Rodriguez R,et al. Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability[J]. Journal of the American Academy of Dermatology,2017,76(4):760-761. doi: 10.1016/j.jaad.2016.10.030
|
[29] |
Eishi K,Bae S J,Ogawa F,et al. Silicone gel sheets relieve pain and pruritus with clinical improvement of keloid: possible target of mast cells[J]. The Journal of Dermatological Treatment,2003,14(4):248-252. doi: 10.1080/09546630310016808
|
[30] |
Xiao Z,Zhang F,Cui Z. Treatment of hypertrophic scars with intralesional botulinum toxin type A injections: a preliminary report[J]. Aesthetic Plastic Surgery,2009,33(3):409-412. doi: 10.1007/s00266-009-9334-z
|
[31] |
Scala J,Vojvodic A,Vojvodic P,et al. Botulin toxin use in scars/Keloids treatment[J]. Open Access Macedonian Journal of Medical Sciences,2019,7(18):2979-2981. doi: 10.3889/oamjms.2019.783
|
[32] |
Xiao Z,Zhang M,Liu Y,et al. Botulinum toxin type a inhibits connective tissue growth factor expression in fibroblasts derived from hypertrophic scar[J]. Aesthetic Plastic Surgery,2011,35(5):802-807. doi: 10.1007/s00266-011-9690-3
|
[33] |
Carmichael N M E,Dostrovsky J O,Charlton M P. Peptide-mediated transdermal delivery of botulinum neurotoxin type A reduces neurogenic inflammation in the skin[J]. Pain,2010,149(2):316-324. doi: 10.1016/j.pain.2010.02.024
|
[34] |
Gupta S,Kalra A. Efficacy and safety of intralesional 5-fluorouracil in the treatment of keloids[J]. Dermatology (Basel,Switzerland),2002,204(2):130-132. doi: 10.1159/000051830
|
[35] |
Aggarwal H,Saxena A,Lubana P S,et al. Treatment of keloids and hypertrophic scars using bleom[J]. Journal of Cosmetic Dermatology,2008,7(1):43-49. doi: 10.1111/j.1473-2165.2008.00360.x
|
[36] |
Zhu R,Yue B,Yang Q,et al. The effect of 595 nm pulsed dye laser on connective tissue growth factor (CTGF) expression in cultured keloid fibroblasts[J]. Lasers in Surgery and Medicine,2015,47(2):203-209. doi: 10.1002/lsm.22334
|
[37] |
Connell P G,Harland C. Treatment of keloid scars with pulsed dye laser and intralesional steroid[J]. Journal of Cutaneous Laser Therapy,2000,2(3):147-150. doi: 10.1080/14628830050516407
|
[38] |
Li W B,Liu S,Zhang M Z,et al. Hyperbaric oxygen therapy relieved pruritus and pain of keloid patients[J]. American Journal of Translational Research,2020,12(2):574-582.
|
[39] |
Klotz T,Kurmis R,Munn Z,et al. Moisturisers in scar management following burn: A survey report[J]. Burns: Journal of the International Society for Burn Injuries,2017,43(5):965-972. doi: 10.1016/j.burns.2017.01.021
|
[40] |
De Decker I,Hoeksema H,Vanlerberghe E,et al. Occlusion and hydration of scars: moisturizers versus silicone gels[J]. Journal of the International Society for Burn Injuries,2023,49(2):365-379. doi: 10.1016/j.burns.2022.04.025
|
[41] |
Nguyen D A,Thai E,Weis S E. Management of Keloid-Associated Pruritus With Topical Crisaborole 2% Ointment: A Case Report[J]. HCA Healthcare Journal of Medicine,2024,5(2):139-143.
|
[42] |
Bissonnette R,Pavel A B,Diaz A,et al. Crisaborole and atopic dermatitis skin biomarkers: An intrapatient randomized trial[J]. The Journal of Allergy and Clinical Immunology,2019,144(5):1274-1289. doi: 10.1016/j.jaci.2019.06.047
|
[43] |
Diaz A,Tan K,He H,et al. Keloid lesions show increased IL-4/IL-13 signaling and respond to Th2-targeting dupilumab therapy[J]. Journal of the European Academy of Dermatology and Venereology,2020,34(4):e161-e164.
|
[44] |
Wong A J S,Song E J. Dupilumab as an adjuvant treatment for keloid-associated symptoms[J]. JAAD Case Reports,2021,13(1):73-74. doi: 10.1016/j.jdcr.2021.04.034
|
[1] | Shaoyan NIE, Susu FAN, Yushan ZHU, Xuerong PENG, Yang WANG, Xuan ZHANG. Protective Effects of Xiyanping Injection on Lipopolysaccharide-induced Acute Lung Injury in Mice. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20241105 |
[2] | Zheng JIA, Zhengjiang XING, Qian LIU, Yibin DU, Bing LI, Ying XIE, Yi ZHAO. Observation and Analysis of Coronary Microcirculation by Establishing Rat Myocardial Ischemia and in Vitro CMECs Hypoxia Model. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20241106 |
[3] | Yanping LI, Xiaolin¹ DONG, Qingyun LI, Hongmei LI, Huan WEI, Yi ZENG. miR-21-5p Alleviates OGD/R-induced Inflammation and Apoptosis of HT22 Cells and Promotes Proliferation by Inhibiting STAT3. Journal of Kunming Medical University, |
[4] | Huawei JIANG, Xia LIU, Yan WANG, Minhui ZHANG, Weidan YIN, Liwei ZHANG. Research Progress on the Pathogenesis of Pterygium. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20230125 |
[5] | Fan XU, Fang-yuan GUO, Yan HE, Xiang-qun WEI. Clinical Analysis of Peripheral Blood Cells and Coagulation Function in Patients with Adenomyosis. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20211124 |
[6] | Li-han YANG, Zhi-bi ZHANG, Hui YANG, Jiang-lan YANG, Dan MAO, Xiao-li YANG, Chao-yu LUO, Yuan ZHANG, Rong-ping ZHANG. Comparative Study on Anti-inflammatory and Antimicrobial Effects for Two Kinds of the Resin Gel. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20210134 |
[7] | Yang Shao Yan , Wu Lu , Zhang Su Xian . . Journal of Kunming Medical University, |
[8] | Na LI, Ying TU, Ying XIONG, Ya-jie NENG, Hong-bin LI, Hong-min LIANG. Association between Lifestyle and Behavior and Skin Physiological Function in Patients with Chronic Pruritus. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20201222 |
[9] | Li Yu Peng , Jiao Jian Lin , Lv Le Chun . Effects of Rutin on Proliferation of Keloid Fibroblasts. Journal of Kunming Medical University, |
[10] | Zhang Fu Hou . Research Progress of Galectin in Mchanism of Venous Trombosis. Journal of Kunming Medical University, |
[11] | Yuan Hua Yuan . . Journal of Kunming Medical University, |
[12] | Li Yan . . Journal of Kunming Medical University, |
[13] | Zhang Yi . . Journal of Kunming Medical University, |
[14] | Liu Yan . . Journal of Kunming Medical University, |
[15] | Zhang Meng Si . . Journal of Kunming Medical University, |
[16] | Fang Ke Wei . . Journal of Kunming Medical University, |
[17] | Su Ying . . Journal of Kunming Medical University, |
[18] | Bai Qing . . Journal of Kunming Medical University, |
[19] | Li Jie . . Journal of Kunming Medical University, |
[20] | Li Yu Xiao . . Journal of Kunming Medical University, |