Exploratory Study on the Ultrasound Characteristics of the Vagus Nerve in a Healthy Han Population in a Hospital in Qujing, Yunnan

Lingli HOU; Yan CHENG; Fang YANG; Junsu YANG; Zizhen ZHANG; Jianjian BAO; Guohui ZHANG; Kang DU

doi:10.12259/j.issn.2095-610X.S20250119

Volume 46 Issue 1

Jan. 2025

Turn off MathJax

Article Contents

Abstract

References

Relative Articles

Article Navigation > Journal of Kunming Medical University > 2025 > 46(1): 129-135

Niu Hua Tao . Three-dimensional Conformal Radiotherapy with Temozolomide in the Treatment of Postoperative Malignant Gliomas[J]. Journal of Kunming Medical University, 2011, 32(12).

Citation:

Lingli HOU, Yan CHENG, Fang YANG, Junsu YANG, Zizhen ZHANG, Jianjian BAO, Guohui ZHANG, Kang DU. Exploratory Study on the Ultrasound Characteristics of the Vagus Nerve in a Healthy Han Population in a Hospital in Qujing, Yunnan[J]. Journal of Kunming Medical University, 2025, 46(1): 129-135. doi: 10.12259/j.issn.2095-610X.S20250119

Niu Hua Tao . Three-dimensional Conformal Radiotherapy with Temozolomide in the Treatment of Postoperative Malignant Gliomas[J]. Journal of Kunming Medical University, 2011, 32(12).

Citation:

PDF( 1966 KB)

Exploratory Study on the Ultrasound Characteristics of the Vagus Nerve in a Healthy Han Population in a Hospital in Qujing, Yunnan

doi: 10.12259/j.issn.2095-610X.S20250119

1.
Ultrasound Department
2.
Neurology Department，The First People’s Hospital of Qujing，Qujing Yunnan 655000，China

Received Date: 2024-04-11
Available Online: 2024-12-30
Publish Date: 2025-01-17

Abstract

Abstract

Objective To explore the characteristics of the cross-sectional area （CSA） of the vagus nerve in a healthy population in Qujing, Yunnan, and its correlation with demographic characteristics. Methods High-resolution nerve ultrasound examinations were conducted on the vagus nerve of 201 healthy volunteers from a hospital in Qujing, Yunnan from September 2022 to March 2023. The CSA was measured through transverse scans of the vagus nerve. The correlation of vagus nerve CSA with age, body mass index （BMI）, and gender was assessed. Results The mean CSA of the bilateral VN were 1.9 mm² （right） and 1.3 mm² （left）, respectively. The average CSA of the right vagus nerve was significantly greater than that of the left （P < 0.001）. In the high-age group （ > 50 years）, the average CSA of the right vagus nerve was significantly higher than that of the low-age group （≤50 years）（P = 0.0142）. However, there was no statistically significant difference in the average CSA of the right vagus nerve between the BMI > 24 kg/m² group and the ≤24 kg/m² group （P = 0.0852）. The average CSA of the left vagus nerve showed no statistically significant differences across different age groups and BMI groups （P > 0.05）, but the average CSA of the bilateral vagus nerve in the male group was greater than that in the female group, with a statistically significant difference （P < 0.05）. Correlation analysis further confirmed a negative correlation between the average CSA of the right vagus nerve and age （r = -0.17, P = 0.0139）. Multiple linear regression models indicated that age （P = 0.007） and gender （P = 0.001） were independent influencing factors for the average CSA of the right vagus nerve. Conclusion In the healthy population of Qujing, Yunnan, the CSA of the right vagus nerve is significantly greater than that of the left, and males also exhibit a significantly greater CSA than females. With increasing age, the vagus nerve gradually becomes thinner.
- Ultrasonography,
- Vagus nerve,
- CSA,
- Healthy population,
- Normal values

FullText(HTML)

References(26)

References

[1]	Chen J,Liu J,Zeng J,et al. Ultrasonographic reference values for assessing normal sciatic nerve ultrasonography in the normal population[J]. J Med Ultrasound,2018,26(2):85-89. doi: 10.4103/JMU.JMU_6_17
[2]	Rasenack M,Décard B F,Schädelin S,et al. Ultrasonographic reference values for peripheral nerves and nerve roots in the normal population of children and adolescents: Study protocol for an observational-prospective trial[J]. BMJ Open,2016,6(12):e14662.
[3]	Kerasnoudis A,Pitarokoili K,Behrendt V,et al. Cross sectional area reference values for sonography of peripheral nerves and brachial plexus[J]. Clin Neurophysiol,2013,124(9):1881-1888. doi: 10.1016/j.clinph.2013.03.007
[4]	Singh K P,Kaur S,Arora V. Reference values for the cross sectional area of normal tibial nerve on high-resolution ultrasonography[J]. J Ultrason,2022,22(90):e144-e152. doi: 10.15557/JoU.2022.0024
[5]	Singh K P,Singh P,Gupta K. Reference values for the cross-sectional area of the normal sciatic nerve using high-resolution ultrasonography[J]. J Ultrason,2021,21(85):e95-e104. doi: 10.15557/JoU.2021.0018
[6]	Yalcin E,Onder B,Akyuz M. Ulnar nerve measurements in healthy individuals to obtain reference values[J]. Rheumatol Int,2013,33(5):1143-1147. doi: 10.1007/s00296-012-2527-9
[7]	Tawfik E A,Walker F O,Cartwright M S. Neuromuscular ultrasound of cranial nerves[J]. J Clin Neurol,2015,11(2):109-121. doi: 10.3988/jcn.2015.11.2.109
[8]	Cartwright M S,Passmore L V,Yoon J S,et al. Cross-sectional area reference values for nerve ultrasonography[J]. Muscle Nerve,2008,37(5):566-571. doi: 10.1002/mus.21009
[9]	Tawfik E A,Walker F O,Cartwright M S,et al. Diagnostic ultrasound of the vagus nerve in patients with diabetes[J]. J Neuroimaging,2017,27(6):589-593. doi: 10.1111/jon.12452
[10]	Niu J,Zhang L,Ding Q,et al. Vagus nerve ultrasound in chronic inflammatory demyelinating polyradiculoneuropathy and Charcot-Marie-Tooth Disease type 1A[J]. J Neuroimaging,2020,30(6):910-916. doi: 10.1111/jon.12747
[11]	Jang J H,Cho C S,Yang K S,et al. Pattern analysis of nerve enlargement using ultrasonography in chronic inflammatory demyelinating polyneuropathy[J]. Clin Neurophysiol,2014,125(9):1893-1899. doi: 10.1016/j.clinph.2013.12.115
[12]	Grimm A,Décard B F,Athanasopoulou I,et al. Nerve ultrasound for differentiation between amyotrophic lateral sclerosis and multifocal motor neuropathy[J]. J Neurol,2015,262(4):870-880. doi: 10.1007/s00415-015-7648-0
[13]	Cartwright M S,Brown M E,Eulitt P,et al. Diagnostic nerve ultrasound in Charcot-Marie-Tooth disease type 1B[J]. Muscle Nerve,2009,40(1):98-102. doi: 10.1002/mus.21292
[14]	Grimm A,Thomaser A L,Peters N,et al. Neurological picture. Vagal hypertrophy in immune-mediated neuropathy visualised with high-resolution ultrasound (HR-US)[J]. J Neurol Neurosurg Psychiatry,2015,86(11):1277-1278. doi: 10.1136/jnnp-2014-308271
[15]	Holzapfel K,Naumann M. Ultrasound detection of vagus nerve atrophy in bulbar amyotrophic lateral sclerosis[J]. J Neuroimaging,2020,30(6):762-765. doi: 10.1111/jon.12761
[16]	Pelz J O,Belau E,Fricke C,et al. Axonal degeneration of the vagus nerve in Parkinson's disease-a high-resolution ultrasound study[J]. Front Neurol,2018,9:951. doi: 10.3389/fneur.2018.00951
[17]	Du K,Xu K,Chu X,et al. Vagus nerve ultrasound in transthyretin familial amyloid polyneuropathy: A pilot study[J]. J Neuroimaging,2022,32(2):285-291. doi: 10.1111/jon.12956
[18]	Pelz J O,Belau E,Henn P,et al. Sonographic evaluation of the vagus nerves: Protocol,reference values,and side-to-side differences[J]. Muscle Nerve,2018,57(5):766-771. doi: 10.1002/mus.25993
[19]	Sindhu D M,Huddar A,Saini J,et al. Cross-sectional area reference values of nerves in the upper and lower extremities using ultrasonography in the Indian population[J]. Ann Indian Acad Neurol,2022,25(3):449-456. doi: 10.4103/aian.aian_727_21
[20]	Boehm J,Scheidl E,Bereczki D,et al. High-resolution ultrasonography of peripheral nerves: Measurements on 14 nerve segments in 56 healthy subjects and reliability assessments[J]. Ultraschall Med,2014,35(5):459-467. doi: 10.1055/s-0033-1356385
[21]	Pelz J O,Busch M,Weinreich A,et al. Evaluation of freehand high-resolution 3-dimensional ultrasound of the median nerve[J]. Muscle Nerve,2017,55(2):206-212. doi: 10.1002/mus.25241
[22]	Pelz J O,Belau E,Menze I,et al. Correlation between sonographic morphology and function of the cervical vagus nerves[J]. Auton Neurosci,2019,220:102552. doi: 10.1016/j.autneu.2019.05.004
[23]	Al-Kureischi K. Topographic anatomy and fiber diameter of the human vagal trunk[J]. Acta Anat (Basel),1979,103(3):252-258. doi: 10.1159/000145022
[24]	Tagliafico A,Martinoli C. Reliability of side-to-side sonographic cross-sectional area measurements of upper extremity nerves in healthy volunteers[J]. J Ultrasound Med,2013,32(3):457-462. doi: 10.7863/jum.2013.32.3.457
[25]	Singh K P,Goindi A S,Gupta K. Reference values for the cross-sectional area of normal radial nerve at two levels using high-resolution ultrasonography[J]. J Ultrason,2021,21(85):e112-e126. doi: 10.15557/JoU.2021.0020
[26]	Tahmaz M,Yoon M S,Schellinger P D,et al. Cross-sectional area in median and ulnar nerve ultrasound correlates with hand volume[J]. Muscle Nerve,2020,62(1):83-88. doi: 10.1002/mus.26881

Relative Articles(20)

Relative Articles

[1]	, . . Journal of Kunming Medical University, 2024, 45(1B): 7-8.
[2]	Xiangbi LI, Yanling HUANG, Yongping LU, Linkun TA, Aitao YIN, Mengxia TANG. Clinical Significance of Uterine Artery and Luteal Blood Flow Doppler Parameters Pregnancy of Uncertain Viability. Journal of Kunming Medical University, 2022, 43(12): 93-98. doi: 10.12259/j.issn.2095-610X.S20221218
[3]	Hu Shun Qin , Lu Xiao Ning , Song Xin Yan , Geng Li , Xu Jing , Chen Min , Li Nan . . Journal of Kunming Medical University, 2020, 41(02): 149-152.
[4]	Jiang-pin XU, Jun MA, Nan XIE, Qian WU, Fan CAO, Rong-ji YAN, Hua WANG. Clinical Application Value of Ultrasound in the Diagnosis of Acute Appendicitis. Journal of Kunming Medical University, 2020, 41(11): 78-82. doi: 10.12259/j.issn.2095-610X.S20201118
[5]	Li Xiao Xue , Xiao Jian Ming , Li Lin . . Journal of Kunming Medical University, 2019, 40(06): 71-75.
[6]	Tao Jian Ping , Qu Qi Cai , Zhou Chen , Li Guan Fei , Shao Ming Kun , Xia Li Bin . . Journal of Kunming Medical University, 2019, 40(04): 107-111.
[7]	Shi Hu Tao , Song Guang Yi , Long Zhi Gang . Magnetic Resonance Imaging Study of Cardiac Atrioventricular Line and Ventricular Systolic Function in Population of Kunming. Journal of Kunming Medical University, 2017, 38(08): 20-24.
[8]	Guo Xue Jun , Miao Chun Mei , Tang Qing Wen , Jin Xue Mei , Yang Yue . Clinical Study on Thyroid Space Occupying Lesion by Ultrasound in Patients with Breast Cancer. Journal of Kunming Medical University, 2016, 37(11): 86-88.
[9]	Cao Wei Han . The Value of Using Ultrasound in Evaluating Neural Stem of the Normal Wrist. Journal of Kunming Medical University,
[10]	Gao Hong . Application Value of Bedside Ultrasound in Diagnosis of Neonatal Severe Pneumonia. Journal of Kunming Medical University,
[11]	Lei Yu . . Journal of Kunming Medical University,
[12]	Li Jian . 超声弹性成像在甲状腺结节鉴别诊断中的临床价值. Journal of Kunming Medical University,
[13]	Gao Hong . . Journal of Kunming Medical University,
[14]	Gai Qi Ming . . Journal of Kunming Medical University,
[15]	Yang Li . . Journal of Kunming Medical University,
[16]	Min Jie Qing . . Journal of Kunming Medical University,
[17]	Zhao Xing Yuan . . Journal of Kunming Medical University,
[18]	. . Journal of Kunming Medical University,
[19]	. Evaluation of Atherosclerosis in Rheumatoid Arthritis Patients with High Lipid Levels by Ultrasonography. Journal of Kunming Medical University,
[20]	. . Journal of Kunming Medical University,