2025 Vol. 46, No. 1
2025, 46(1): 1-8.
doi: 10.12259/j.issn.2095-610X.S20250101
Abstract:
Thrombotic diseases refer to a group of conditions characterized by abnormal blood coagulation within blood vessels, leading to the formation of blood clots and a series of clinical symptoms. This includes diseases such as deep vein thrombosis in the...
Thrombotic diseases refer to a group of conditions characterized by abnormal blood coagulation within blood vessels, leading to the formation of blood clots and a series of clinical symptoms. This includes diseases such as deep vein thrombosis in the...
2025, 46(1): 9-15.
doi: 10.12259/j.issn.2095-610X.S20250102
Abstract:
Objective To understand the refractive progression of myopic school-aged children in ethnic minority areas of Yunnan and explore related factors. Methods Based on an existing cohort, a first follow-up survey was conducted from October 2020 to June 2...
2025, 46(1): 16-22.
doi: 10.12259/j.issn.2095-610X.S20250103
Abstract:
Objective To explore and analyze adverse drug events (ADE) signals of azithromycin, identify common adverse events and suspected adverse reactions that occur easily in the real clinical application of azithromycin. Methods The adverse drug event rep...
2025, 46(1): 23-35.
doi: 10.12259/j.issn.2095-610X.S20250104
Abstract:
Objective To utilize single-cell and peripheral blood transcriptomic data from 3D brain organoids, combined with machine learning, to analyze the role of mitochondrial autophagy genes in schizophrenia (SCZ). Methods By integrating two machine learni...
Galangin Inhibits the Migration and Invasion of Cervical Cancer Hela Cells Through Hippo/YAP Pathway
2025, 46(1): 36-42.
doi: 10.12259/j.issn.2095-610X.S20250105
Abstract:
Objective To investigate the effects of galangin on the migration and invasion abilities of cervical cancer Hela cells and its potential mechanisms. Methods Hela cells were treated with different concentrations of galangin (0, 5, 10, 20, 40, 60, 80,...
2025, 46(1): 43-50.
doi: 10.12259/j.issn.2095-610X.S20250106
Abstract:
Objective To explore the clinical efficacy and safety of immediate laparoscopic radical prostatectomy immediately following the diagnosis of locally advanced prostate cancer. Methods A retrospective analysis was performed for 63 patients with locall...
2025, 46(1): 51-59.
doi: 10.12259/j.issn.2095-610X.S20250107
Abstract:
Objective To analysis the efficacy and safety of antiviral therapy in patients with chronic hepatitis B virus in indeterminate phase based on the new guidelines (2022 Edition of the Guidelines for the Prevention and Treatment of Chronic Hepatitis B)....
2025, 46(1): 60-67.
doi: 10.12259/j.issn.2095-610X.S20250108
Abstract:
Objective To understand the current status of stigma among lung cancer patients in Yunnan and analyze its influencing factors. Methods A convenience sampling method was employed to select 248 lung cancer patients from a tertiary cancer hospital in Y...
2025, 46(1): 68-77.
doi: 10.12259/j.issn.2095-610X.S20250109
Abstract:
Objective To explore the influencing factors of self injury or suicide in adolescent patients with depression. Methods A total of 96 adolescents who were diagnosed with depressive disorder at Yunnan Psychiatirc Hospital and Kunming Psychiatirc Hospi...
GJB4 Gene Expression in Relation to Clinical and Pathological Features of Pancreatic Cancer Patients
2025, 46(1): 78-86.
doi: 10.12259/j.issn.2095-610X.S20250110
Abstract:
Objective To investigate the expression of GJB4 gene in pancreatic cancer tissue and its correlation with clinicopathology. Methods The expression levels of GJB4 mRNA in pancreatic cancer and adjacent cancer tissues were analyzed using bioinformatic...
2025, 46(1): 87-92.
doi: 10.12259/j.issn.2095-610X.S20250111
Abstract:
Objective To investigate the refractive development parameters of primary school students aged 7 to 12 years in Chuxiong City, Yunnan Province, analyze their relationship with equivalent spherical power (SE), and evaluate the monitoring role of refra...
2025, 46(1): 93-98.
doi: 10.12259/j.issn.2095-610X.S20250112
Abstract:
Objective To analyze the correlation of preoperative collagen lectin-11 (CL-11), urinary nitrite, and urinary heparin-binding protein (U-HBP) with postoperative urinary sepsis (US) in patients with kidney stones, and to explore their predictive value...
2025, 46(1): 99-104.
doi: 10.12259/j.issn.2095-610X.S20250113
Abstract:
Objective To measure the Young's modulus values of the quadriceps muscles (rectus femoris, vastus intermedius, vastus lateralis, vastus medialis) and tendons in Parkinson's disease (PD) patients using real-time shear wave elastography (SWE) technolog...
2025, 46(1): 105-110.
doi: 10.12259/j.issn.2095-610X.S20250114
Abstract:
Objective To explore the mediating effect of hope between self-perceived burden and quality of life in patients with recurrent malignant tumors. Methods A cross-sectional survey was conducted using convenience sampling, selecting 204 patients with re...
2025, 46(1): 111-116.
doi: 10.12259/j.issn.2095-610X.S20250115
Abstract:
Objective To explore the expression changes of KIAA1199 and Linc00673 genes in non-small cell lung cancer patients before and after chemotherapy, and to further evaluate the potential value of these two genes as molecular markers in predicting chemot...
2025, 46(1): 117-122.
doi: 10.12259/j.issn.2095-610X.S20250117
Abstract:
Objective To explore the effects of modified prone ventilation combined with bronchoscopic alveolar lavage on respiratory mechanics and hemodynamics in children with Acute Respiratory Distress Syndrome (ARDS), as well as to evaluate the clinical trea...
2025, 46(1): 123-128.
doi: 10.12259/j.issn.2095-610X.S20250118
Abstract:
Objective To explore the expression changes of IGF-1 and IGFBP-3 in childhood obesity and their diagnostic value. Methods Blood samples and corresponding clinical information were collected from patients attending Kunming Children's Hospital from De...
2025, 46(1): 129-135.
doi: 10.12259/j.issn.2095-610X.S20250119
Abstract:
Objective To explore the characteristics of the cross-sectional area (CSA) of the vagus nerve in a healthy population in Qujing, Yunnan, and its correlation with demographic characteristics. Methods High-resolution nerve ultrasound examinations were...
2025, 46(1): 136-141.
doi: 10.12259/j.issn.2095-610X.S20250120
Abstract:
Objective To analyze the expression and diagnostic value of procalcitonin (PCT), white blood cell count (WBC), and C-reactive protein (CRP) in respiratory infections in the intensive care unit (ICU), and their correlation with the clinical pulmonary ...
2025, 46(1): 142-147.
doi: 10.12259/j.issn.2095-610X.S20250121
Abstract:
Objective To investigate the expression and significance of CD4+CD25+ regulatory T cells (CD4+CD25+Treg) and soluble CD30 (sCD30) in peripheral blood of lymphoma patients. Methods A total of 83 lymphoma patients admitted to Beijing Aerospace General ...
2025, 46(1): 148-153.
doi: 10.12259/j.issn.2095-610X.S20250122
Abstract:
Bacteriophages possess the ability to infect and kill bacteria and have now been applied in various oral diseases, providing new insights for the prevention and treatment of oral diseases. They are expected to become a novel biological antibacterial ...
Bacteriophages possess the ability to infect and kill bacteria and have now been applied in various oral diseases, providing new insights for the prevention and treatment of oral diseases. They are expected to become a novel biological antibacterial ...
2025, 46(1): 154-159.
doi: 10.12259/j.issn.2095-610X.S20250123
Abstract:
Solitay iliac aneurysms are a rare clinical condition characterized by insidious onset. Once they rupture, treatment becomes difficult, and the mortality rate is extremely high. Therefore, it is extremely important to detect the disease, classify it ...
Solitay iliac aneurysms are a rare clinical condition characterized by insidious onset. Once they rupture, treatment becomes difficult, and the mortality rate is extremely high. Therefore, it is extremely important to detect the disease, classify it ...
2025, 46(1): 160-166.
doi: 10.12259/j.issn.2095-610X.S20250124
Abstract:
Objective To explore the impact of the clinical internship model at the on-campus rehabilitation outpatient clinic on the clinical practice abilities and employment intentions of students in the physical therapy program. Methods A total of 60 studen...
2025, 46(1): 167-172.
doi: 10.12259/j.issn.2095-610X.S20250125
Abstract:
Objective To investigate the impact of temperature intervention on pain and catheterization outcomes in premature infants undergoing peripherally inserted central catheter (PICC) placement. Methods A total of 70 premature infants who underwent PICC ...