Association between C-reactive Protein/Albumin Ratio and Long-term Prognosis in Elderly Patients with Heart Failure

Jian-pei SU; Wei-meng TIAN; Jun GU; Mi-yu HE

doi:10.12259/j.issn.2095-610X.S20201236

Volume 41 Issue 12

Dec. 2019

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Article Navigation > Journal of Kunming Medical University > 2020 > 41(12): 128-132

Jian-pei SU, Wei-meng TIAN, Jun GU, Mi-yu HE. Association between C-reactive Protein/Albumin Ratio and Long-term Prognosis in Elderly Patients with Heart Failure[J]. Journal of Kunming Medical University, 2020, 41(12): 128-132. doi: 10.12259/j.issn.2095-610X.S20201236

Citation:

Jian-pei SU, Wei-meng TIAN, Jun GU, Mi-yu HE. Association between C-reactive Protein/Albumin Ratio and Long-term Prognosis in Elderly Patients with Heart Failure[J]. Journal of Kunming Medical University, 2020, 41(12): 128-132. doi: 10.12259/j.issn.2095-610X.S20201236

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Association between C-reactive Protein/Albumin Ratio and Long-term Prognosis in Elderly Patients with Heart Failure

doi: 10.12259/j.issn.2095-610X.S20201236

Dept. of Geriatrics，The 2nd Hospital of Kunming，Kunming Yunnan 650204，China

Received Date: 2020-02-08
Publish Date: 2019-12-26

Abstract

Abstract

Objective To investigate the association between the ratio of C-reactive protein to albumin（HS-CRP/Alb）and long-term prognosis in elderly patients with heart failure. Methods A total of 125 aged 65-70 patients with heart failure were enrolled as the research subjects, and retrospective cohort analysis was conducted. Subjects were divided into 2 groups based on prognosis as good prognosis group（n = 75）, and poor prognosis group（n = 50）. We compared hs CRP/propagated ratio, NYHA heart function classification, brain natriuretic peptide and blood sodium, total cholesterol, hemoglobin and other general information of the two groups; and usd multiariable COX regression and Logistic regression analysis of CRP/propagated ratio of capacity to evaluate the prognosis of patients with senile heart failure as well as the related factors affecting the ratio. Results The hs-crp/Alb ratio in the good prognosis group was significantly lower than that in the poor prognosis group（P > 0.05）. In the poor prognosis group; the hs-crp/Alb ratio of > 0.38 was an independent risk factor for poor prognosis, while ageing, high level of brain peptide, high NYHA grade of heart function, low serum sodium, low total cholesterol and low level of hemoglobin were independent risk factors for low hs-crp/Alb ratio. Conclusion C-reactive protein/albumin ratio is a good indicator of prognosis in patients with heart failure.
- HS-CRP/Alb,
- Heart failure,
- Brain natriuretic peptide,
- Prognosis

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References(15)

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