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Citation: Hao YAN, Qi YUE, Dan GU, Hui TIAN, Hui LI, Rongqing LI. Dosimetric Differences between Tomo and Monaco Planning Systems and Comparison of Gamma Pass Rates in Preoperative Radiotherapy for Rectal Cancer Patients[J]. Journal of Kunming Medical University, 2022, 43(1): 67-72. doi: 10.12259/j.issn.2095-610X.S20220132

Dosimetric Differences between Tomo and Monaco Planning Systems and Comparison of Gamma Pass Rates in Preoperative Radiotherapy for Rectal Cancer Patients

doi: 10.12259/j.issn.2095-610X.S20220132
  • Received Date: 2021-12-20
    Available Online: 2021-12-20
  • Publish Date: 2022-01-15
  •   Objectives   To investigate the dosimetric differences between TOMO and Monaco planning systems in preoperative radiotherapy for rectal cancer and the comparison of Gamma pass rate, so as to provide a reference for the selection of clinical treatment.  Methods   A total of 20 patients with preoperative radiotherapy for rectal cancer admitted from December 2019 to January 2021 were selected, TOMO and Monaco planning were performed for these 20 patients respectively. The dose-volume histogram was used to evaluate the dose distribution of the target area and the radiation dose of the organs at risk. The differences between the two planning systems in the dosimetry of the planned target area and endangering organs were analyzed and compared, and the gamma pass rates of the two schemes were compared.  Results   Both TOMO and Monaco plans could meet the prescription dose requirement of target area. The HI and CI of PGTV target of Tomo plan were better than those of Monaco planning system, and the CI of PCTV target area was also superior to that of Monaco plan system (P < 0.001). In terms of organs at risk, compared with Monaco planning system, the mean values of Dmean, V50, V40, V30 of bladder, Dmean, V30, V20, V15 of bilateral femoral head, and pelvic V50 indicators in TOMO plan were lower (P < 0.05). The execution time of Tomo’ s planning machine was 4.3 times that of Monaco’ s, and the execution time of Tomo’ s planning machine was 1.31 times that of Monaco’ s (P < 0.05). The mean Gamma pass rate of Tomo plan was higher than that of Monaco plan (P < 0.05).  Conclusion   The TOMO plan system design for preoperative radiotherapy of rectal cancer patients can significantly improve the target uniformity and conformal degree, and can also reduce the dose of normal tissues. The plan Gamma has a higher pass rate, but the treatment time is longer. The treatment time of Monaco planning system is significantly shortened.
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