Clinical Study of Extracorporeal Shock Wave Combined with Sodium Hyaluronate in the Treatment of Knee Osteoarthritis

Tao SHI; Youqing HUANG; Xiaofeng HE; Ya NING; Shikuang ZANG; Yan CHEN; Dan WANG; Yuewei LIANG

doi:10.12259/j.issn.2095-610X.S20220311

Volume 43 Issue 3

Mar. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(3): 80-85

Tao SHI, Youqing HUANG, Xiaofeng HE, Ya NING, Shikuang ZANG, Yan CHEN, Dan WANG, Yuewei LIANG. Clinical Study of Extracorporeal Shock Wave Combined with Sodium Hyaluronate in the Treatment of Knee Osteoarthritis[J]. Journal of Kunming Medical University, 2022, 43(3): 80-85. doi: 10.12259/j.issn.2095-610X.S20220311

Citation:

Tao SHI, Youqing HUANG, Xiaofeng HE, Ya NING, Shikuang ZANG, Yan CHEN, Dan WANG, Yuewei LIANG. Clinical Study of Extracorporeal Shock Wave Combined with Sodium Hyaluronate in the Treatment of Knee Osteoarthritis[J]. Journal of Kunming Medical University, 2022, 43(3): 80-85. doi: 10.12259/j.issn.2095-610X.S20220311

Citation:

Tao SHI, Youqing HUANG, Xiaofeng HE, Ya NING, Shikuang ZANG, Yan CHEN, Dan WANG, Yuewei LIANG. Clinical Study of Extracorporeal Shock Wave Combined with Sodium Hyaluronate in the Treatment of Knee Osteoarthritis[J]. Journal of Kunming Medical University, 2022, 43(3): 80-85. doi: 10.12259/j.issn.2095-610X.S20220311

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Clinical Study of Extracorporeal Shock Wave Combined with Sodium Hyaluronate in the Treatment of Knee Osteoarthritis

doi: 10.12259/j.issn.2095-610X.S20220311

Dept. of Pain，The 2nd Affiliated Hospital of Kunming Medical University， Kunming Yunnan 650101，China

Received Date: 2022-01-14
Available Online: 2022-02-18
Publish Date: 2022-03-22

Abstract

Abstract

Objective To observe the clinical efficacy of external radiative shock wave combined with sodium hyaluronate injection in the treatment of knee osteoarthritis （KOA）. Methods Sixty-two patients with KOA be divided into observation group and control group randomly, with 31 cases in each group. The observation group included 13 males and 18 females, the mean age was （62.35±9.70） years old, and the course of disease was （3.06±1.49） years. There were 16 males and 15 females in the control group, the mean age was （60.87±1.56） years old, and the course of disease was （2.74±1.53） years. The Extracorporeal Shockwave therapy （ESWT） was given firstly , then the Intra-articular injection of hyaluronic acid （HA） was injected 2 days later in the observation group. The control group was treated with HA only 1 week. Both of the groups were treated once a week for 5 weeks. The Visual Analogue Scale （VAS） and Western Ontario and McMaster University Osteoarthritis Index （WOMAC） were used to evaluate the difference in efficacy between the two groups, at the time of before the treatment, 1 week after the treatment and 3 months after that.KOA patients were divided into observation group Ⅱ and control group Ⅱ according to Kellgren-Lawrence grading （Ⅱ, Ⅲ）. VAS score and WOMAC score of observation group Ⅲ and control group Ⅲ were compared before and after treatment, respectively. Results The VAS score and WOMAC score in both group were significantly lower than those before at the time of 1 week and 3 months after treatment （P < 0.05）, while 1 week after treatment and 3 months after treatment the VAS and WOMAC scores in the observation group were lower than those in the control group （P < 0.05）. The WOMAC score of the observation group was further decreased after 3 months than 1 week after treatment （P < 0.05）. In kellgren-Lawrence class Ⅱ and Ⅲ patients, the scores of observation group and control group decreased after treatment compared with before treatment （P < 0.05）, VAS of observation group decreased 1 week after treatment in class Ⅱ group, but the difference was not statistically significant, WOMAC score decreased （P < 0.05）. VAS and WOMAC scores of kellgren-Lawrence grade Ⅲ patients were lower than those of control group 3 months after treatment （P < 0.05）, VAS and WOMAC scores of Kellgren-Lawrence grade Ⅲ patients were lower than those of control group 1 week and 3 months after treatment （P < 0.05）. Conclusion The ESWT combined with HA can significantly reduce the joint pain and improve knee joint mobility more effectively than HA alone in the treatment of KOA.
- Extracorporeal shock wave,
- Sodium hyaluronate,
- Knee osteoarthritis

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