Lijuan YIN, Lingyun BAO, Jing YAO. Effect of Mechanical Vibration Assisted Expectoration in Neonatal Infectious Pneumonia[J]. Journal of Kunming Medical University, 2022, 43(3): 166-170. doi: 10.12259/j.issn.2095-610X.S20220315
Citation: Wenhua XIA, Xiang SUN, Jianlin SHAO. Feasibility of Optic Nerve Sheath Diameter to Guide the Treatment of Dehydration in Patients Undergoing Glioma Surgery[J]. Journal of Kunming Medical University, 2022, 43(6): 117-121. doi: 10.12259/j.issn.2095-610X.S20220620

Feasibility of Optic Nerve Sheath Diameter to Guide the Treatment of Dehydration in Patients Undergoing Glioma Surgery

doi: 10.12259/j.issn.2095-610X.S20220620
  • Received Date: 2022-02-08
    Available Online: 2022-06-07
  • Publish Date: 2022-06-30
  •   Objective  To investigate the feasibility of ultrasonic measurement of optic nerve sheath diameter (ONSD) in the treatment of dehydration of intracranial hypertension (ICH) in patients undergoing glioma surgery.   Methods   A total of 40 patients with cranial hypertension who underwent elective frontal glioma resection were randomly divided into 2 groups (n = 20). After 10 minutes of endotracheal intubation, Group M was given 20% mannitol 0.5 g/kg intravenously within 15 minute; Group C was given the same amount of normal saline intravenously within 15 minutes. ONSD values of both eyes were measured before anesthesia induction (T0), immediately after endotracheal intubation (T1), at the beginning of drug infusion (T2), 30 min after drug infusion (T3), immediately after surgery (T4), and 24 h after surgery (T5). The levels of VEGF-A, MMP-9 and ET-1 in serum at each time were detected. Cerebral relaxation score (BRS) was recorded when the dura was opened.   Results   At T3, T4 and T5, the ONSD value and serum concentrations of VEGF-A, MMP-9 and ET-1 in group M were significantly lower than those in group C (P < 0.05). BRS score in M group was significantly lower than that in C group (P < 0.05).   Conclusion  For glioma patients with intracranial hypertension before operation, dehydration treatment in advance under the guidance of optic nerve sheath diameter can effectively reduce cerebral edema.
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