Correlation between NLR Value and Prognosis in Patients with Acute Ischemic Stroke before and after Revascularization

Yike ZHU; Junsu YANG; Fang QIAN; Haohao WU; Baogang HUANG

doi:10.12259/j.issn.2095-610X.S20220815

Volume 43 Issue 8

Jul. 2022

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Yike ZHU, Junsu YANG, Fang QIAN, Haohao WU, Baogang HUANG. Correlation between NLR Value and Prognosis in Patients with Acute Ischemic Stroke before and after Revascularization[J]. Journal of Kunming Medical University, 2022, 43(8): 100-105. doi: 10.12259/j.issn.2095-610X.S20220815

Citation:

Yike ZHU, Junsu YANG, Fang QIAN, Haohao WU, Baogang HUANG. Correlation between NLR Value and Prognosis in Patients with Acute Ischemic Stroke before and after Revascularization[J]. Journal of Kunming Medical University, 2022, 43(8): 100-105. doi: 10.12259/j.issn.2095-610X.S20220815

Citation:

Yike ZHU, Junsu YANG, Fang QIAN, Haohao WU, Baogang HUANG. Correlation between NLR Value and Prognosis in Patients with Acute Ischemic Stroke before and after Revascularization[J]. Journal of Kunming Medical University, 2022, 43(8): 100-105. doi: 10.12259/j.issn.2095-610X.S20220815

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Correlation between NLR Value and Prognosis in Patients with Acute Ischemic Stroke before and after Revascularization

doi: 10.12259/j.issn.2095-610X.S20220815

Dept. of Neurology，Qujing Hospital Affiliated to Kunming Medical University，Qujing 655000，China

Received Date: 2022-04-22
Available Online: 2022-07-20
Publish Date: 2022-07-28

Abstract

Abstract

Objective To study the influencing factors of poor prognosis before and after revascularization of acute ischemic stroke, so as to provide more biomarkers for prognosis prediction. Methods A total of 179 patients with acute ischemic stroke who received revascularization therapy （including intravenous thrombolysis, mechanical thrombectomy, or both） admitted to the Department of Neurology and The Department of Neurointervention of Qujing Hospital Affiliated to Kunming Medical University from December 2020 to October 2021 were collected. According to mRS score after 3 months, the patients were divided into good prognosis group （mRS < 3） and poor prognosis group （mRS≥3）. General data, clinical test indicators, NLR value and NIHSS score before and after revascularization were compared between the two groups, and independent risk factors of patients with poor prognosis were further analyzed. Results There are siginificant differences in triglyceride, total cholesterol, c-reactive protein, NIHSS score, the number of neutrophils and percentage of the hospital, lymphocyte count and percentage, NLR value and reascularization 8 hours after the number of white blood cells, neutrophils and percentage, lymphocyte count and percentage, NLR value between the two groups （P < 0.05）. Multivariate Logistic regression analysis showed that admission NIHSS score （OR=1.123, 95%CI 1.065-1.184, P < 0.05） was an independent risk factor for poor prognosis 3 months after revascularization in AIS patients, with a clinical diagnostic cut-off value of 11. The NLR values of the poor prognosis group before and after revascularization were higher than those of the good prognosis group, the difference was statistically significant （P < 0.05）. The NLR values of AIS patients after revascularization were higher than those before revascularization, the difference was statistically significant （P < 0.05）. Conclusion NIHSS score at admission is an independent risk factor for poor prognosis at 3 months in patients with AIS revascularization. Changes in NLR in AIS patients before and after revascularization showed an upward trend, and NLR in the poor prognosis group was higher than that in the good prognosis group before and after revascularization, but it was not an independent risk factor for poor prognosis in AIS patients 3 months after revascularization.
- Acute ischemic stroke,
- Neutrophil to lymphocyte ratio,
- Revascularization,
- The prognosis

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References(16)

References

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