Heng ZHANG, Jin-song ZHANG, Lei XING, Bo-bo XIONG. Clinical Analysis of Flexible Ureteroscope in Solitary Kidney and Non-solitary Kidney Stones[J]. Journal of Kunming Medical University, 2021, 42(2): 91-95. doi: 10.12259/j.issn.2095-610X.S20210224
Citation: Xiaofeng ZHU, Guangping ZHOU, Laicang WANG, Houjun ZHOU, Xin GENG, Hualin YU, Jinghui LI, Peng BAI. Clinical Effect of Reoperation for Recurrent Glioma[J]. Journal of Kunming Medical University, 2022, 43(9): 77-83. doi: 10.12259/j.issn.2095-610X.S20220920

Clinical Effect of Reoperation for Recurrent Glioma

doi: 10.12259/j.issn.2095-610X.S20220920
  • Received Date: 2022-06-19
    Available Online: 2022-09-08
  • Publish Date: 2022-09-29
  •   Objective  To analyze the clinical effect of multimodality microsurgery on recurrent gliomas, and to explore the diagnosis and treatment of recurrent gliomas.  Methods  Data of 28 patients with recurrent GLIOMAS who underwent reoperation from September 2017 to December 2020 in the Department of Neurosurgery of a tertiary grade A hospital in Kunming were collected and analyzed retrospectively, After the reoperation, the Karnofsky neurological function score (KPS) was used to evaluate the clinical efficacy, and the imaging data was used to evaluate the degree of tumor resection, the postoperative comparison of pathological changes of recurrent glioma, postoperative adjuvant treatment, follow-up patient survival time and other overall effects. Graphpad Prism (V8.4.2.679) software was used to analyze the data and graph. The difference in KPS scores before and after the operation was tested in pairs.   Results  28 patients were treated with reoperations to varying degrees. Postoperative imaging confirmed that 21 cases of tumors were totally resected, 5 cases were subtotal resected, and 2 cases had tumor biopsy. Postoperative complications occurred in 22 patients. The clinical symptoms before discharge were improved in 24 cases compared with that before the operation, with an improvement rate of 85.7%. The mean KPS score was 66.07 ± 7.37 before the operation and 72.14 ± 11.00 one month after the operation.The differences were statistically significant. Postoperative pathology showed the progression of Malignancy in 8 cases. The mean survival time of 28 patients were (7.98 ± 6.42) months and the longest survival time were 24 months.  Conclusion  The combined application of multi-modality and multi-technique microsurgery is a relatively minimally invasive and effective treatment for recurrent glioma. The surgical effect is good, and it can be used as an option for surgical resection of recurrent glioma.
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