Clinical Application of Doxazosin Mesylate in Female Overactive Bladder

Xiaoqian YANG; Yuquan ZHANG; Huitao WANG; Tongxin YANG; Tao CHEN; Yuting WENG; Kewei FANG

doi:10.12259/j.issn.2095-610X.S20220926

Volume 43 Issue 9

Sep. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(9): 66-69

Xiaoqian YANG, Yuquan ZHANG, Huitao WANG, Tongxin YANG, Tao CHEN, Yuting WENG, Kewei FANG. Clinical Application of Doxazosin Mesylate in Female Overactive Bladder[J]. Journal of Kunming Medical University, 2022, 43(9): 66-69. doi: 10.12259/j.issn.2095-610X.S20220926

Citation:

Xiaoqian YANG, Yuquan ZHANG, Huitao WANG, Tongxin YANG, Tao CHEN, Yuting WENG, Kewei FANG. Clinical Application of Doxazosin Mesylate in Female Overactive Bladder[J]. Journal of Kunming Medical University, 2022, 43(9): 66-69. doi: 10.12259/j.issn.2095-610X.S20220926

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Clinical Application of Doxazosin Mesylate in Female Overactive Bladder

doi: 10.12259/j.issn.2095-610X.S20220926

1.
Dept. of Urology，The 2nd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101
2.
The 3rd Surgical Department of Diqing Tibetan Autonomous Prefecture People’s Hospital，Shangri-La, Yunnan 674499，China

Received Date: 2022-06-08
Available Online: 2022-09-07
Publish Date: 2022-09-29

Abstract

Abstract

Objective To study the clinical therapeutic effect of doxazosin mesylate on female patients with overactive bladder （OAB） complicated with micturition symptoms. Methods A retrospective analysis was made of 68 female patients who were diagnosed with OAB and complicated with micturition symptoms in the Outpatient Department of Urology of the Second Affiliated Hospital of Kunming Medical University from June to December 2021 due to lower urinary tract symptoms （LUTS）. Among them, 36 cases were treated with doxazosin mesylate combined with solinacin succinate tablets as the treatment group; 32 cases were treated with solinacin succinate tablets as the control group. After 12 weeks of the treatment, the symptoms before and after the treatment were compared using American Urological Association symptom score （AUAss）, overactive bladder symptom score （OABSS） and quality of life （QOL） score. Results After 12 weeks of the treatment, the scores of OABSS, AUAss and QOL in the treatment group and the control group were significantly improved compared with those before the treatment （P < 0.05）. There was significant difference in AUAss between the treatment group and the control group （P < 0.05）. Conclusion Doxazosin mesylate combined with sorinaxin succinate tablets can improve lower urinary tract symptoms and quality of life in female patients with OAB complicated with micturition symptoms.
- Doxazosin mesylate,
- Female overactive bladder,
- Micturition symptoms,
- Medication.

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References(13)

References

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