Volume 43 Issue 9
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Citation: Caiying ZHANG, Zhengping KUI, Qiong WANG, Xiaolong ZHAO, Xiaomei HOU, Zhiye QI. Perinatal Risk Factors of Neonatal Hyperthyrotropinemia[J]. Journal of Kunming Medical University, 2022, 43(9): 48-52. doi: 10.12259/j.issn.2095-610X.S20220929
shu

Perinatal Risk Factors of Neonatal Hyperthyrotropinemia

doi: 10.12259/j.issn.2095-610X.S20220929
  • 1.

    Dept. of Pediatrics

  • 2.

    Neonatal Screening Center

  • 3.

    Dept. of Obstetrics，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

  • Received Date: 2022-06-02
    Available Online: 2022-09-16
  • Publish Date: 2022-09-29
    Abstract
  •   Objective  To investigate the association between neonatal Hyperthyrotropinemia （HT） and perinatal risk factors.   Methods  A case-control study was conducted among 109 newborns with HT （case group） and 127 newborns without HT （control group） in the First Affiliated Hospital of Kunming Medical University from Jan. 2016 to Dec. 2020. Univariate and multivariate logistic regression analysis was conducted to identify the perinatal risk factors to neonatal HT.   Results  Univariate analysis indicated that the incidence of advanced maternal age and preterm delivery in the case group were significantly higher than those in the control group. The results of multivariate logistic regression analysis showed that advanced maternal age （OR = 2.320, 95%CI: 1.099～4.897）and preterm delivery （OR = 2.960, 95%CI: 1.354～6.473） increased the risk of neonatal HT.   Conclusion  Advanced maternal age and preterm delivery were the independent perinatal risk factors for neonatal HT. Efforts should be made to provide high quality pregnancy care, decrease the perinatal risk factors of neonatal HT, and to reduce the incidence of neonatal HT.
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    • References(27)
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