Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve

Zexing YANG; Ya WEN; Cunmei SU; Huawei WANG; Meng RAO; Yuhang ZHENG; Limei HE

doi:10.12259/j.issn.2095-610X.S20221211

Volume 43 Issue 12

Dec. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(12): 53-57

Zexing YANG, Ya WEN, Cunmei SU, Huawei WANG, Meng RAO, Yuhang ZHENG, Limei HE. Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve[J]. Journal of Kunming Medical University, 2022, 43(12): 53-57. doi: 10.12259/j.issn.2095-610X.S20221211

Citation:

Zexing YANG, Ya WEN, Cunmei SU, Huawei WANG, Meng RAO, Yuhang ZHENG, Limei HE. Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve[J]. Journal of Kunming Medical University, 2022, 43(12): 53-57. doi: 10.12259/j.issn.2095-610X.S20221211

Citation:

Zexing YANG, Ya WEN, Cunmei SU, Huawei WANG, Meng RAO, Yuhang ZHENG, Limei HE. Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve[J]. Journal of Kunming Medical University, 2022, 43(12): 53-57. doi: 10.12259/j.issn.2095-610X.S20221211

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Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve

doi: 10.12259/j.issn.2095-610X.S20221211

1.
Dept. of Reproductive Genetics，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032
2.
Yunnan Provincial Key Laboratory of Birth Regulation and Healthy Birth of Ethnic Minorities，Western Key Laboratory of Healthy Birth before Pregnancy，Kunming Yunnan 650032
3.
Wenzhou Center for Disease Control and Prevention，Wenzhou Zhejiang 325000
4.
Dept. of Epidemiology，School of Public Health, Kunming Medical University，Kunming Yunnan 650500，China

Received Date: 2022-05-10
Publish Date: 2022-12-25

Abstract

Abstract

Objective To compare the clinical outcomes of PPOS protocal and mild-stimulation protocal in patients with diminished ovarian reserve function during assisted reproduction and pregnancy. Methods Patients with DOR who underwent the first and second generation of test-tube babies（IVF/ICSI） in the First Affiliated Hospital of Kunming Medical University from April 2021 to April 2022 were retrospectively analyzed. A total of 294 cycles were included and divided into 2 groups（group A: PPOS group, group B: mild-stimulation group）. The medication, embryo status and pregnancy outcomes were compared between the two groups. Results Initiation dose of Gn, total Gn dose, HCG dose on trigger day in group A were significantly higher than those in group B（P < 0.05）; LH on HCG day in group A was lower than that in group B（ P < 0.05）. The number of eggs, embryos and high quality embryos in group A were higher than those in group B（ P < 0.05）. Conclusion The clinical outcomes of the PPOS group were better than the mild-stimulation group.
- IVF/ICSI,
- Diminished ovarian reservee,
- Mild stimulation protocol,
- PPOS protocal

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References(19)

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