Efficacy of Conventional Ultrasound and Contrast-enhanced Ultrasound in Preoperative Diagnosis of Lateral Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma

Jianfei LU; Rui BU; Xiaoyan LIU; Xing ZHANG; Yu DING; Ran ZHANG

doi:10.12259/j.issn.2095-610X.S20221214

Volume 43 Issue 12

Dec. 2022

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Jianfei LU, Rui BU, Xiaoyan LIU, Xing ZHANG, Yu DING, Ran ZHANG. Efficacy of Conventional Ultrasound and Contrast-enhanced Ultrasound in Preoperative Diagnosis of Lateral Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma[J]. Journal of Kunming Medical University, 2022, 43(12): 75-80. doi: 10.12259/j.issn.2095-610X.S20221214

Citation:

Jianfei LU, Rui BU, Xiaoyan LIU, Xing ZHANG, Yu DING, Ran ZHANG. Efficacy of Conventional Ultrasound and Contrast-enhanced Ultrasound in Preoperative Diagnosis of Lateral Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma[J]. Journal of Kunming Medical University, 2022, 43(12): 75-80. doi: 10.12259/j.issn.2095-610X.S20221214

Citation:

Jianfei LU, Rui BU, Xiaoyan LIU, Xing ZHANG, Yu DING, Ran ZHANG. Efficacy of Conventional Ultrasound and Contrast-enhanced Ultrasound in Preoperative Diagnosis of Lateral Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma[J]. Journal of Kunming Medical University, 2022, 43(12): 75-80. doi: 10.12259/j.issn.2095-610X.S20221214

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Efficacy of Conventional Ultrasound and Contrast-enhanced Ultrasound in Preoperative Diagnosis of Lateral Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma

doi: 10.12259/j.issn.2095-610X.S20221214

1.
Dept. of Ultrasound
2.
Dept. of cardiology，The 2nd Affiliated Hospital of Kunming Medical University, Kunming Yunnan 650101，China

Received Date: 2022-08-02
Available Online: 2022-12-05
Publish Date: 2022-12-25

Abstract

Abstract

Objective To investigate the ultransonic characteristics of conventional ultrasound （US）combined with Contrast-enhanced ultrasound （CEUS） in the pre-operative diagnosis effectiveness of lateral cervical lymph node metastasis （LCLNM）from papillary thyroid carcinoma （PTC）, and to evaluate its efficacy in preoperative diagnosis of PTC lateral cervical lymph node metastasis. Methods A total of 80 patients who received PTC surgery and lateral cervical lymph node dissection in the Second Affiliated Hospital of Kunming Medical University were selected, and 126 lymph node ultrasonography data were obtained. Postoperative pathology confirmed that 81 lymph nodes were metastatic PTC and 45 lymph nodes were non-metastatic. The ultrasonographic features of lymph node metastasis were observed by conventional ultrasound （US） and contrast-enhanced ultrasound （CEUS）. Compared with the pathological results, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of US, CEUS and combined application in the preoperative diagnosis of LCLNM in PTC patients were calculated. Results The ultrasonographic features of metastatic lymph nodes were mostly lymphatic portal disappearance or deviation. Cortical echo was non-uniform hypoecho, internal mass hyperecho and calcification, blood flow types were mostly peripheral type and mixed type, and blood flow grades were mostly Adler grade 2 and grade 3; compared with the non-metastatic group, the difference was statistically significant （P < 0.05）. The ultrasonographic characteristics of metastatic lymph nodes detected by CEUS were mostly centriotype and type Ⅱ, followed by type Ⅲ. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of the combination of US and CEUS were superior to those of US or CEUS alone in the diagnosis of PTC lateral cervical lymph node metastasis. Conclusion Preoperative conventional ultrasound combined with CEUS can improve the diagnostic efficacy of lateral cervical lymph node metastasis from PTC.
- Ultrasonography,
- Contrast-enhanced ultrasound,
- Papillary thyroid carcinoma,
- Lateral cervical lymph node metastasis

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