Application of High-flow Nasal Cannula Oxygen Therapy in High-altitude Hypoxemia

Xiaoxue LIU; Li YANG; Chuanyun QIAN

doi:10.12259/j.issn.2095-610X.S20221216

Volume 43 Issue 12

Dec. 2022

Turn off MathJax

Article Contents

Article Navigation > Journal of Kunming Medical University > 2022 > 43(12): 88-92

Xiaoxue LIU, Li YANG, Chuanyun QIAN. Application of High-flow Nasal Cannula Oxygen Therapy in High-altitude Hypoxemia[J]. Journal of Kunming Medical University, 2022, 43(12): 88-92. doi: 10.12259/j.issn.2095-610X.S20221216

Citation:

Xiaoxue LIU, Li YANG, Chuanyun QIAN. Application of High-flow Nasal Cannula Oxygen Therapy in High-altitude Hypoxemia[J]. Journal of Kunming Medical University, 2022, 43(12): 88-92. doi: 10.12259/j.issn.2095-610X.S20221216

Citation:

PDF( 631 KB)

Application of High-flow Nasal Cannula Oxygen Therapy in High-altitude Hypoxemia

doi: 10.12259/j.issn.2095-610X.S20221216

Dept. of Emergency Medicine，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

Received Date: 2022-10-18
Available Online: 2022-12-06
Publish Date: 2022-12-25

Abstract

Abstract

Objective To explore the efficacy of high-flow nasal cannula oxygen therapy on oxygenation in populations at altitudes above 2500 meters. Methods Participants were recruited from medium-altitude Kunming （about 1891 m above sea level） to quickly enter higher altitude Lhasa （about 3650 m above sea level）. Participants inhaled air using high-flow nasal cannula oxygen therapy in Lhasa. The pulse oxygen saturation （SpO₂）, respiratory rate, heart rate and blood pressure were compared before and after the use of high-flow nasal cannula oxygen therapy . Results In high altitude area, the high flow nasal canula oxygen therapy went well and smoothly. After high-flow nasal catheter oxygen therapy, SpO₂ improved and respiratory rate decreased with the increase of inhaled gas flow, the difference was statistically significant （P < 0.05）. After using high-flow nasal cannula oxygen therapy equipment for air inhalation, SpO₂ improved and respiratory rate decreased with the increase of inhaled gas flow, the difference was statistically significant （P < 0.05）. Conclusion High-flow nasal cannula oxygen therapy not only improved participants’ oxygenation, it decreased the effort of breathing, and has potential clinical value in the treatment of high-altitude hypoxemia .
- Lhasa,
- High-altitude hypoxemia,
- High-flow nasal cannula oxygen therapy,
- Pulse oximetry,
- Respiratory rate

FullText(HTML)

References(19)

References

[1]	Roach R C,Greene E R,Schoene R B,et al. Arterial oxygen saturation for prediction of acute mountain sickness[J]. Aviation,Space,and Environmental Medicine,1998,69(12):1182-1185.
[2]	Kasic J F,Yaron M,Nicholas R A,et al. Treatment of acute mountain sickness:Hyperbaric versus oxygen therapy[J]. Annals of Emergency Medicine,1991,20(10):1109-1112. doi: 10.1016/S0196-0644(05)81385-X
[3]	Grimminger J,Richter M,Tello K,et al. Thin air resulting in high pressure:Mountain sickness and hypoxia-induced pulmonary hypertension[J]. Canadian Respiratory Journal,2017,2017:8381653.
[4]	Prince T S, Thurman J, Huebner K. Acute mountain sickness[M]. In: StatPearls. Treasure Island （FL）: StatPearls Publishing, 2022, 56.
[5]	Sharma S, Danckers M, Sanghavi D, et al. High flow nasal cannula[M]. In: StatPearls. Treasure Island （FL）: StatPearls Publishing, 2022, 205.
[6]	Riera J,Perez P,Cortes J,et al. Effect of high-flow nasal cannula and body position on end-expiratory lung volume:A cohort study using electrical impedance tomography[J]. Respiratory Care,2013,58(4):589-596. doi: 10.4187/respcare.02086
[7]	Onodera Y,Akimoto R,Suzuki H,et al. A high-flow nasal cannula system with relatively low flow effectively washes out CO2 from the anatomical dead space in a sophisticated respiratory model made by a 3D printer[J]. Intensive Care Medicine Experimental,2018,6(1):7. doi: 10.1186/s40635-018-0172-7
[8]	Roca O,Perez-Teran P,Masclans J R,et al. Patients with New York Heart Association class III heart failure may benefit with high flow nasal cannula supportive therapy:High flow nasal cannula in heart failure[J]. Journal of Critical Care,2013,28(5):741-746. doi: 10.1016/j.jcrc.2013.02.007
[9]	Ricard J D. High flow nasal oxygen in acute respiratory failure[J]. Minerva Anestesiologica,2012,78(7):836-841.
[10]	Delorme M,Bouchard P A,Simon M,et al. Effects of high-flow nasal cannula on the work of breathing in patients recovering from acute respiratory failure[J]. Critical Care Medicine,2017,45(12):1981-1988. doi: 10.1097/CCM.0000000000002693
[11]	Ni Y N,Luo J,Yu H,et al. Can high-flow nasal cannula reduce the rate of endotracheal intubation in adult patients with acute respiratory failure compared with conventional oxygen therapy and noninvasive positive pressure ventilation? A systematic review and meta-analysis[J]. Chest,2017,151(4):764-775. doi: 10.1016/j.chest.2017.01.004
[12]	Monro-Somerville T,Sim M,Ruddy J,et al. The effect of high-flow nasal cannula oxygen therapy on mortality and intubation rate in acute respiratory failure:A systematic review and meta-analysis[J]. Critical Care Medicine,2017,45(4):449-456. doi: 10.1097/CCM.0000000000002091
[13]	Oczkowski S,Ergan B,Bos L,et al. ERS clinical practice guidelines:High-flow nasal cannula in acute respiratory failure[J]. Eur Respir J,2022,59(4):2101574. doi: 10.1183/13993003.01574-2021
[14]	Carratala Perales J M,Llorens P,Brouzet B,et al. High-Flow therapy via nasal cannula in acute heart failure[J]. Revista Espanola de Cardiologia,2011,64(8):723-725. doi: 10.1016/j.recesp.2010.10.034
[15]	Moriyama K,Satoh T,Motoyasu A,et al. High-Flow nasal cannula therapy in a patient with reperfusion pulmonary edema following percutaneous transluminal pulmonary angioplasty[J]. Case Reports in Pulmonology,2014,2014:837612.
[16]	Atwood C W Jr,Camhi S,Little K C,et al. Impact of heated humidified high flow air via nasal cannula on respiratory effort in patients with chronic obstructive pulmonary disease[J]. Chronic Obstructive Pulmonary Diseases (Miami,Fla),2017,4(4):279-286. doi: 10.15326/jcopdf.4.4.2017.0169
[17]	Chatila W,Nugent T,Vance G,et al. The effects of high-flow vs low-flow oxygen on exercise in advanced obstructive airways disease[J]. Chest,2004,126(4):1108-1115. doi: 10.1378/chest.126.4.1108
[18]	Hernandez G,Vaquero C,Colinas L,et al. Effect of postextubation high-flow nasal cannula vs noninvasive ventilation on reintubation and postextubation respiratory failure in high-risk patients:A Randomized Clinical Trial[J]. JAMA,2016,316(15):1565-1574. doi: 10.1001/jama.2016.14194
[19]	Hernandez G,Vaquero C,Gonzalez P,et al. Effect of postextubation high-flow nasal cannula vs conventional oxygen therapy on reintubation in low-risk patients:A randomized clinical trial[J]. JAMA,2016,315(13):1354-1361. doi: 10.1001/jama.2016.2711

Relative Articles(20)

Relative Articles

[1]	Juan LI, Chengjun DENG, Shuli HE, Ying LI, Meifen WANG. Clinical Characteristics and Polymorphism of UGT1A1 Gene in 53 Cases of Congenital Hyperbilirubinemia in Yunnan. Journal of Kunming Medical University, 2024, 45(5): 136-143. doi: 10.12259/j.issn.2095-610X.S20240521
[2]	Jianhong XU, Zhengmin REN, Yanjiao ZHAO, Shiyun LI, Ruijuan ZHANG, Faguo ZHANG. Screening of Congenital Heart Disease at Different Time in Neonates in Anning Area by Auscultation Combined with Pulse Oximetry. Journal of Kunming Medical University, 2023, 44(4): 128-132. doi: 10.12259/j.issn.2095-610X.S20230425
[3]	Caiying ZHANG, Zhengping KUI, Qiong WANG, Xiaolong ZHAO, Xiaomei HOU, Zhiye QI. Perinatal Risk Factors of Neonatal Hyperthyrotropinemia. Journal of Kunming Medical University, 2022, 43(9): 48-52. doi: 10.12259/j.issn.2095-610X.S20220929
[4]	Xiao-zhi XU, Jing-hui YANG. Comparison of Exchange Transfusion and Intensive Phototherapy in the Treatment of Neonatal Hyperbilirubinemia. Journal of Kunming Medical University, 2020, 41(11): 44-48. doi: 10.12259/j.issn.2095-610X.S20201131
[5]	Qing-qing XIONG, Xiao-dong LUO, Bu-fang FU, Jia-yi ZHONG, Guo-lian HE. Effects of Dexmedetomidine on Respiration in Postoperative Patients Undergone General Anesthesia at High Altitude Areas. Journal of Kunming Medical University, 2020, 41(12): 85-88. doi: 10.12259/j.issn.2095-610X.S20201224
[6]	Jing YANG, Shu-xian WANG, Zhu ZHOU. Effect of Aerobic Exercise and Nutritional Management in Maintenance Hemodialysis Patients with Malnutrition. Journal of Kunming Medical University, 2020, 41(11): 68-71. doi: 10.12259/j.issn.2095-610X.S20201123
[7]	Jiang Yu Hui , Liu Ling , He Can Lin , Li Yang . . Journal of Kunming Medical University, 2019, 40(04): 20-22.
[8]	Chen Hong Mei , Liu Li . . Journal of Kunming Medical University, 2019, 40(07): 116-119.
[9]	Zeng Xiao Ying , Zhang Chuan , Le Tao , Jiang Li Dong , Wang Xi , Ye Dan , Ke Li , Zhang Yi . . Journal of Kunming Medical University, 2019, 40(12): 80-85.
[10]	Xu Li Jie , Pan Ling , Fan Yan Qian , Li Hui Fang , Lei Ying , Li Min . . Journal of Kunming Medical University, 2019, 40(02): 97-101.
[11]	Zhang Le , Xia Jia Wei , Chen Hai Yun , Huang Ying . . Journal of Kunming Medical University, 2018, 39(11): 93-97.
[12]	Li Zhi Wei , Li Chao , Dong Quan , Ma Ji Tao , Wang Li Lan , Li Yang , Zhang Hong Xing , Yang Li Na . Comparison between Nasal High Flow Oxygen Therapy and Non-invasive Ventilation Care for Post-extubation Hypoxemia after Abdominal Surgery in ICU. Journal of Kunming Medical University, 2017, 38(01): 65-69.
[13]	Lai 碁. The Application Time of NIMV Treatment in ACS Patients with Hypoxaemia. Journal of Kunming Medical University,
[14]	Li Lan Jiang . . Journal of Kunming Medical University,
[15]	Dai Bai Zhang . . Journal of Kunming Medical University,
[16]	He Xue Zhong . . Journal of Kunming Medical University,
[17]	Ye Ying . . Journal of Kunming Medical University,
[18]	Ma Shan . Effects of Liangxuehuoxue Drugs on Hyperoxia Induced Retinal Neovascular HIF-1 and NF-кB Expression in Mice. Journal of Kunming Medical University, 2012, 33(10): 1-1.
[19]	Wang Ya Nan . . Journal of Kunming Medical University,
[20]	Fei Xian Min . . Journal of Kunming Medical University,