Clinical Value of Ultrasound-guided FNA and FNA-TG in Identification of Lymph Node Metastasis of Papillary Thyroid Carcinoma

Hailin ZHANG; Mei ZHU; Yang YANG; Lin WEI; Xi CHEN; Bailing WU

doi:10.12259/j.issn.2095-610X.S20221220

Volume 43 Issue 12

Dec. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(12): 105-110

Hailin ZHANG, Mei ZHU, Yang YANG, Lin WEI, Xi CHEN, Bailing WU. Clinical Value of Ultrasound-guided FNA and FNA-TG in Identification of Lymph Node Metastasis of Papillary Thyroid Carcinoma[J]. Journal of Kunming Medical University, 2022, 43(12): 105-110. doi: 10.12259/j.issn.2095-610X.S20221220

Citation:

Hailin ZHANG, Mei ZHU, Yang YANG, Lin WEI, Xi CHEN, Bailing WU. Clinical Value of Ultrasound-guided FNA and FNA-TG in Identification of Lymph Node Metastasis of Papillary Thyroid Carcinoma[J]. Journal of Kunming Medical University, 2022, 43(12): 105-110. doi: 10.12259/j.issn.2095-610X.S20221220

Citation:

Hailin ZHANG, Mei ZHU, Yang YANG, Lin WEI, Xi CHEN, Bailing WU. Clinical Value of Ultrasound-guided FNA and FNA-TG in Identification of Lymph Node Metastasis of Papillary Thyroid Carcinoma[J]. Journal of Kunming Medical University, 2022, 43(12): 105-110. doi: 10.12259/j.issn.2095-610X.S20221220

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Clinical Value of Ultrasound-guided FNA and FNA-TG in Identification of Lymph Node Metastasis of Papillary Thyroid Carcinoma

doi: 10.12259/j.issn.2095-610X.S20221220

Hailin ZHANG^{1, 2},
Mei ZHU^{1
,
,},
Yang YANG¹,
Lin WEI¹,
Xi CHEN¹,
Bailing WU¹

1.
Dept. of Ultrasound，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032
2.
Dept. of Ultrasound，The 3rd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650100，China

Received Date: 2022-09-07
Available Online: 2022-12-06
Publish Date: 2022-12-25

Abstract

Abstract

Objective To explore the diagnostic significance of FNA-Tg for lymph nodes with suspected cervical thyroid papillary carcinoma metastasis on the basis of ultrasonic detection and guidance and accurate biopsy of FNA, and establish the threshold of FNA-TG. Methods 74 lymph nodes with suspected metastasis of thyroid cancer were evaluated by fine needle aspiration and analysed pathologically. Lymph nodes were evaluated by comparing FNA alone, FNA-TG value with serum Tg, and drawing ROC to obtain the best diagnostic value of FNA-TG, and the sensitivity, specificity and accuracy of positive results were evaluated. Results There were significant differences in calcification, cortex-medullary boundary, abnormal blood supply and aspect ratio in the diagnosis of cervical lymph node metastasis of papillary thyroid carcinoma （P < 0.05）. The above four indexes had the highest sensitivity in the diagnosis of lymph node metastasis of thyroid cancer. Calcification, multiple hyperecho, cystic changes and elastic imaging had higher hardness specificity, and the accuracy of cortex-medulla boundary and aspect ratio was the highest. The sensitivity, specificity and accuracy of FNA were 75%, 100% and 87.84%. The sensitivity, specificity and accuracy of FNA-Tg/ serum Tg value > 1 were 97.22%, 100% and 98.65%. ROC curve was drawn to obtain the optimal diagnostic threshold of FNA-Tg as 0.575 ng/mL. Conclusion FNA-Tg/ serum Tg > 1, as the diagnostic criteria for lymph node metastasis of papillary thyroid cancer, can better avoid the disadvantages caused by many factors and effectively reduce the error rate, and should be the first choice for the auxiliary diagnosis of lymph node metastasis of papillary thyroid cancer.
- Papillary thyroid carcinoma,
- Biospy,
- Fine-needle,
- Lymphatic metastasis

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References(15)

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