Application of High Epidural Combined General Anesthesia in Laparoscopic Liver Resection

Weixing DING; Siyan WANG; Chen ZHOU; Jianyou TIAN; Yalin TAO; Ting LI; Huijuan PENG

doi:10.12259/j.issn.2095-610X.S20230203

Volume 44 Issue 2

Feb. 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(2): 144-149

Weixing DING, Siyan WANG, Chen ZHOU, Jianyou TIAN, Yalin TAO, Ting LI, Huijuan PENG. Application of High Epidural Combined General Anesthesia in Laparoscopic Liver Resection[J]. Journal of Kunming Medical University, 2023, 44(2): 144-149. doi: 10.12259/j.issn.2095-610X.S20230203

Citation:

Weixing DING, Siyan WANG, Chen ZHOU, Jianyou TIAN, Yalin TAO, Ting LI, Huijuan PENG. Application of High Epidural Combined General Anesthesia in Laparoscopic Liver Resection[J]. Journal of Kunming Medical University, 2023, 44(2): 144-149. doi: 10.12259/j.issn.2095-610X.S20230203

Citation:

Weixing DING, Siyan WANG, Chen ZHOU, Jianyou TIAN, Yalin TAO, Ting LI, Huijuan PENG. Application of High Epidural Combined General Anesthesia in Laparoscopic Liver Resection[J]. Journal of Kunming Medical University, 2023, 44(2): 144-149. doi: 10.12259/j.issn.2095-610X.S20230203

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Application of High Epidural Combined General Anesthesia in Laparoscopic Liver Resection

doi: 10.12259/j.issn.2095-610X.S20230203

1.
Dept. of Pain
2.
Dept. of Anesthesiology，The Second People’s Hospital of Qujing，Qujing Yunnan 655099
3.
Dept. of Anesthesiology
4.
Laboratory Medicine Department，The Second Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China

Received Date: 2022-12-17
Available Online: 2023-01-31
Publish Date: 2023-02-25

Abstract

Abstract

Objective To investigate the application of high epidural combined general anesthesia in laparoscopic liver resection. Methods A total of 86 patients with laparoscopic hepatectomy in the Second People’s Hospital of Qujing City from March 2020 to September 2022 were randomly selected and divided into 2 groups with 43 cases in each group by the number table method. The control group received general anesthesia during perioperative period, while the observation group received high epidural combined general anesthesia. The perioperative hemodynamic level, Perioperative hemodynamic level, T lymphocyte subsets, intraoperative blood loss and anesthesia related complications were recorded in the two groups. Results The perioperative hemodynamics of the two groups increased first and then decreased. The levels of SBP, DBP and HR at T1 and T2 in the two groups were higher than those at T0, and the differences were statistically significant （P < 0.05 ）. The levels of SBP, DBP and HR at T1 and T2 in the observation group were lower than those in the control group, and the differences were statistically significant （ P < 0.05 ）. The level of T lymphocytes in the two groups decreased in different degrees at 48 h after operation. The levels of CD3⁺, CD4⁺ and CD4⁺/CD8⁺ in the observation group were significantly higher than those in the control group （P < 0.05 ）. There was no significant difference being found in the comparison of the incidences of apnea, delayed recovery, hypoxemia, respiratory depression and urinary retention between the two groups （P > 0.05 ）. Conclusion The application of high epidural combined general anesthesia in laparoscopic liver resection can stabilize the hemodynamic level, reduce the central venous pressure of patients, and does not increase intraoperative bleeding, has little effect on the level of T lymphocyte subsets, and has high anesthesia safety, which is worthy of promotion and application.
- High epidural,
- General anesthesia,
- Laparoscopic liver resection,
- T lymphocyte subsets,
- Security

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References(19)

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