Analysis on the Application of Optical Coherence Tomographic and Quantitative Flow Ratio in Intermediate In-stent Restenosis Lesions

Ziwei ZHANG; Xiaojuan PAN; Jihong ZOU; Jun YANG; Jialin ZHENG; Jie BAI; Jiong TANG; Xurui ZHANG; Feng QI

doi:10.12259/j.issn.2095-610X.S20230327

Volume 44 Issue 3

Mar. 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(3): 113-119

Ziwei ZHANG, Xiaojuan PAN, Jihong ZOU, Jun YANG, Jialin ZHENG, Jie BAI, Jiong TANG, Xurui ZHANG, Feng QI. Analysis on the Application of Optical Coherence Tomographic and Quantitative Flow Ratio in Intermediate In-stent Restenosis Lesions[J]. Journal of Kunming Medical University, 2023, 44(3): 113-119. doi: 10.12259/j.issn.2095-610X.S20230327

Citation:

Ziwei ZHANG, Xiaojuan PAN, Jihong ZOU, Jun YANG, Jialin ZHENG, Jie BAI, Jiong TANG, Xurui ZHANG, Feng QI. Analysis on the Application of Optical Coherence Tomographic and Quantitative Flow Ratio in Intermediate In-stent Restenosis Lesions[J]. Journal of Kunming Medical University, 2023, 44(3): 113-119. doi: 10.12259/j.issn.2095-610X.S20230327

Citation:

Ziwei ZHANG, Xiaojuan PAN, Jihong ZOU, Jun YANG, Jialin ZHENG, Jie BAI, Jiong TANG, Xurui ZHANG, Feng QI. Analysis on the Application of Optical Coherence Tomographic and Quantitative Flow Ratio in Intermediate In-stent Restenosis Lesions[J]. Journal of Kunming Medical University, 2023, 44(3): 113-119. doi: 10.12259/j.issn.2095-610X.S20230327

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Analysis on the Application of Optical Coherence Tomographic and Quantitative Flow Ratio in Intermediate In-stent Restenosis Lesions

doi: 10.12259/j.issn.2095-610X.S20230327

Dept. of Center for Coronary Heart Disease，Fu Wai Yunnan Cardiovascular Hospital，Kunming Yunnan 650032，China

Received Date: 2022-06-04
Available Online: 2023-03-02
Publish Date: 2023-03-25

Abstract

Abstract

Objective To observe the effect of combined guidance of optical coherence tomographic （OCT） and quantitative flow ratio （QFR） in patients with In-stent restenosis （ISR） of intermediate severity. Methods Patients with intermediate ISR lesions were performed PCI or given OMT under the guidance combined OCT imaging and QFR. PCI was performed if QFR was ≤0.80 or QFR > 0.8 but OCT showed minimal luminal area < 2.0 mm² and the in-stent plaque was unstable and more apt to rupture. Patients with QFR > 0.8 and negative OCT results were given optimal medical therapies, and major adverse cardiac events were assessed at the end of follow-up. The pre-defined primary endpoint was the composite of major adverse cardiac events or recurrent angina at one year. Results A total of 48 patients （with 57 intermediate ISR lesions ） were enrolled. There are 29 lesions of QFR （-）OCT （-）; 16 lesions of QFR （+）OCT （+）, 8 lesions of QFR （-）OCT （+） and 4 lesions of QFR （+）OCT （-）. We found low occurrence （5.3%） of the primary endpoint of major adverse cardiac events or recurrent angina after one year follow-up.No significant difference was found in the incidence of major adverse cardiac events between the 4 groups. Conclusions In patients with intermediate ISR lesions, Combined OCT and QFR Guidance can provide useful prognostic information, reduce the number of unnecessary PCI Procedures and is associated with a lower occurrence of the composite of major adverse cardiac events
- Optical coherence tomography,
- Quantitative flow ratio,
- In-stent restenosis,
- Intermediate lesion

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References(28)

References

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