Research Progress of Autophagy in the Development and Treatment of Bladder Cancer

Shi CHEN; Shi FU; Zhiyong TAN; Jiansong WANG; Haifeng WANG

doi:10.12259/j.issn.2095-610X.S20230503

Volume 44 Issue 5

May 2023

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Shi CHEN, Shi FU, Zhiyong TAN, Jiansong WANG, Haifeng WANG. Research Progress of Autophagy in the Development and Treatment of Bladder Cancer[J]. Journal of Kunming Medical University, 2023, 44(5): 168-174. doi: 10.12259/j.issn.2095-610X.S20230503

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Shi CHEN, Shi FU, Zhiyong TAN, Jiansong WANG, Haifeng WANG. Research Progress of Autophagy in the Development and Treatment of Bladder Cancer[J]. Journal of Kunming Medical University, 2023, 44(5): 168-174. doi: 10.12259/j.issn.2095-610X.S20230503

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Research Progress of Autophagy in the Development and Treatment of Bladder Cancer

doi: 10.12259/j.issn.2095-610X.S20230503

Dept. of Urology，The 2nd Affiliated Hospital of Kunming Medical University，Yunnan Urinary System Disease Clinical Medical Center，Kunming Yunnan 650101，China

Received Date: 2023-01-01
Available Online: 2023-05-12
Publish Date: 2023-05-25

Abstract

Abstract

Autophagy is a self-digestive process of cells degrading intracellular substances through lysosomes and is considered to be an important protection mechanism for tumors to maintain survival under stress conditions. A large number of evidence shows that autophagy is a double-edged sword, which can suppress the occurrence of tumors and promote the survival and growth of tumors by different signaling pathways. Therefore, more and more scholars believe that autophagy is expected to become a new strategy for tumor treatment. This paper summarizes the biological behavior of autophagy regulation of bladder cancer invasion, metastasis, and the latest progress in the treatment of bladder cancer and provides new ideas for the development and treatment of autophagy-targeted antitumor drugs.
- Bladder cancer,
- Autophagy,
- Tumor therapy,
- Drug resistance

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References(38)

References

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