Clinical Study on the Effect of Cognitive Behavioral Therapy for Insomnia on Patients with Parkinson’s Disease with Insomnia

Mengshu YANG; Xiaoyun KONG; Huan LI; Yanwei ZOU; Yihao WANG; Ci DONG

doi:10.12259/j.issn.2095-610X.S20230806

Volume 44 Issue 8

Aug. 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(8): 117-122

Mengshu YANG, Xiaoyun KONG, Huan LI, Yanwei ZOU, Yihao WANG, Ci DONG. Clinical Study on the Effect of Cognitive Behavioral Therapy for Insomnia on Patients with Parkinson’s Disease with Insomnia[J]. Journal of Kunming Medical University, 2023, 44(8): 117-122. doi: 10.12259/j.issn.2095-610X.S20230806

Citation:

Mengshu YANG, Xiaoyun KONG, Huan LI, Yanwei ZOU, Yihao WANG, Ci DONG. Clinical Study on the Effect of Cognitive Behavioral Therapy for Insomnia on Patients with Parkinson’s Disease with Insomnia[J]. Journal of Kunming Medical University, 2023, 44(8): 117-122. doi: 10.12259/j.issn.2095-610X.S20230806

Citation:

Mengshu YANG, Xiaoyun KONG, Huan LI, Yanwei ZOU, Yihao WANG, Ci DONG. Clinical Study on the Effect of Cognitive Behavioral Therapy for Insomnia on Patients with Parkinson’s Disease with Insomnia[J]. Journal of Kunming Medical University, 2023, 44(8): 117-122. doi: 10.12259/j.issn.2095-610X.S20230806

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Clinical Study on the Effect of Cognitive Behavioral Therapy for Insomnia on Patients with Parkinson’s Disease with Insomnia

doi: 10.12259/j.issn.2095-610X.S20230806

Dept. of Neurology，The 1st Hospital of Hebei Medical University， Shijiazhuang Hebei 050031，China

Received Date: 2023-06-18
Publish Date: 2023-08-25

Abstract

Abstract

Objective To investigate the effect of cognitive behavioural therapy for insomnia （CBT-I） intervention on sleep quality and mood in Parkinson’s disease patients with insomnia. Methods Parkinson’s disease patients with insomnia who were hospitalized in a tertiary hospital in Hebei from January 2021 to March 2022 were selected as the study subjects. A random number table method was used for randomization. The control group was given conventional care, while the experimental group was given cognitive behavioural therapy of CBT-I insomnia for 8 weeks on top of this. All patients were routinely given anti-Parkinson’s disease medication. The Pittsburgh Sleep Quality Index （PSQI） scale, Insomnia Severity Index （ISI） scale, sleep log, Hamilton Depression Inventory （HAMD₁₇） and Hamilton Anxiety Inventory （HAMA₁₄） were used for outcome assessment before and after the intervention. Results The differences in PSQI scale, ISI scale, sleep latency （SOL）, total sleep time （TST）, HAMD₁₇ and HAMA₁₄ scores between the test group and the control group after the intervention were statistically significant （P < 0.05）, while the differences in sleep efficiency （SE） between the two groups were not statistically significant （ P > 0.05）. Conclusion Cognitive behavioural therapy for insomnia is effective in improving sleep quality and improving anxiety and depression in patients with Parkinson’s disease with insomnia.
- Cognitive-behavioral therapy for insomnia,
- Parkinson’s disease,
- Insomnia,
- Sleep quality

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References(30)

References

[1]	郭配,张晓韬,李秀华. 帕金森病睡眠障碍的研究进展[J]. 国际神经病学神经外科学杂志,2017,44(3):332-335. doi: 10.16636/j.cnki.jinn.2017.03.025
[2]	中华医学会神经病学分会帕金森病及运动障碍学组,中国医师协会神经内科医师分会帕金森病及运动障碍学组. 中国帕金森病睡眠障碍管理专家共识[J]. 中华神经科杂志,2022,55(5):441-451. doi: 10.3760/cma.j.cn113694-20211123-00828
[3]	Liu C F,Wang T,Zhan S Q,et al. Management Recommendations on Sleep Disturbance of Patients with Parkinson’s Disease[J]. Chin Med J (Engl),2018,131(24):2976-2985. doi: 10.4103/0366-6999.247210
[4]	Rutten S,Vriend C,Berendse H W,et al. Anxiety,depression and sleep disorders in Parkinson’s disease:A complex interaction between body and mind[J]. Tijdschr Psychiatr,2020,62(1):62-72.
[5]	Chan N Y,Chan JWY,Li SX,et al. Non-pharmacological Approaches for Management of Insomnia[J]. Neurotherapeutics,2021,18(1):32-43. doi: 10.1007/s13311-021-01029-2
[6]	肖敏,黄金,赵雪. 认知行为疗法在成人慢性失眠中的应用现状[J]. 护理研究,2018,32(16):2514-2517. doi: 10.12102/j.issn.1009-6493.2018.16.007
[7]	中华医学会神经病学分会帕金森病及运动障碍学组,中国医师协会神经内科医师分会帕金森病及运动障碍专业委员会. 中国帕金森病的诊断标准(2016版)[J]. 中华神经科杂志,2016,49(4):268-271. doi: 10.3760/cma.j.issn.1006-7876.2016.04.002
[8]	中国失眠症诊断和治疗指南（一）[J]. 临床医学研究与实践, 2017, 2（27）: 201.
[9]	Hoehn M M,Yahr M D. Parkinsonism: onset,progression and mortality[J]. Neurology,1967,17(5):427-442. doi: 10.1212/WNL.17.5.427
[10]	Spielman A J,Caruso L S,Glovinsky P B. A behavioral perspective on insomnia treatment[J]. Psychiatr Clin North Am,1987,10(4):541-53. doi: 10.1016/S0193-953X(18)30532-X
[11]	马桂月,沈志莹,乔莉,等. 认知行为疗法对高血压焦虑抑郁患者干预效果研究进展[J]. 中华高血压杂志,2021,29(4):328-332. doi: 10.16439/j.issn.1673-7245.2021.04.005
[12]	Tsai P S,Wang S Y,Wang M Y,et al. Psychometric evaluation of the Chinese version of the Pittsburgh Sleep Quality Index (CPSQI) in primary insomnia and control subjects[J]. Qual Life Res,2005,14(8):1943-1952.、. doi: 10.1007/s11136-005-4346-x
[13]	Bastien C H,Vallières A,Morin C M. Validation of the Insomnia Severity Index as an outcome measure for insomnia research[J]. Sleep Med,2001,2(4):297-307. doi: 10.1016/S1389-9457(00)00065-4
[14]	Hamilton M. A rating scale for depression[J]. Neurol Neurosurg Psychiatry,1960,23(1):56-62. doi: 10.1136/jnnp.23.1.56
[15]	Hamilton M. The assessment of anxiety states by rating[J]. Br J Med Psychol,1959,32(1):50-55. doi: 10.1111/j.2044-8341.1959.tb00467.x
[16]	Stefani A,Högl B. Sleep in Parkinson's disease[J]. Neuropsychopharmacology,2020,45(1):121-128. doi: 10.1038/s41386-019-0448-y
[17]	Pont-Sunyer C,Iranzo A,Gaig C,et al. Sleep disorders in Parkinsonian and nonparkinsonian LRRK2 mutation carriers[J]. PLoS One,2015,10(7):e132368.
[18]	O’Dowd S,Galna B,Morris R,et al. Poor sleep quality and progression of gait impairment in an incident Parkinson’s disease cohort[J]. J Parkinsons Dis,2017,7(3):465-470. doi: 10.3233/JPD-161062
[19]	Adler C H, Thorpy M J. Sleep issues in Parkinson’s disease[J]. Neurology, 2005, 64（12 Suppl 3）: S12-20.
[20]	Kaynak D, Kiziltan G, Kaynak H, Benbir G, Uysal O. Sleep and sleepiness in patients with Parkinson’s disease before and after dopaminergic treatment[J]. Eur J Neurol, 2005, 12（3）: 199-207.
[21]	Zhang Y,Zhao J H,Huang D Y,et al. Multiple comorbid sleep disorders adversely affect quality of life in Parkinson’s disease patients[J]. NPJ Parkinsons Dis,2020,6:25. doi: 10.1038/s41531-020-00126-x
[22]	Rios Romenets S,Creti L,Fichten C,et al. Doxepin and cognitive behavioural therapy for insomnia in patients with Parkinson’s disease - a randomized study[J]. Parkinsonism Relat Disord,2013,19(7):670-675.
[23]	İçel S,Başoğul C. Effects of progressive muscle relaxation training with music therapy on sleep and anger of patients at Community Mental Health Center[J]. Complement Ther Clin Pract,2021,43:101338. doi: 10.1016/j.ctcp.2021.101338
[24]	Sun J,Kang J,Wang P,et al. Self-relaxation training can improve sleep quality and cognitive functions in the older: a one-year randomised controlled trial[J]. J Clin Nurs,2013,22(9-10):1270-1280. doi: 10.1111/jocn.12096
[25]	Yang H,Petrini M. Effect of cognitive behavior therapy on sleep disorder in Parkinson’s disease in China:a pilot study:treatment for Parkinson’s disease[J]. Nurs Health Sci,2012,14(4):458-463.
[26]	Herath T B,Withana M,Rodrigo C,et al. Prevalence and associations for symptoms of depression in patients with Parkinson’s disease: a Sri Lankan experience[J]. Int J Ment Health Syst,2016,10:47. doi: 10.1186/s13033-016-0079-1
[27]	Upneja A,Paul B S,Jain D,et al. Anxiety in Parkinson’s Disease: Correlation with Depression and Quality of Life[J]. J Neurosci Rural Pract,2021,12(2):323-328.
[28]	Braak H,Del Tredici K,Rüb U,et al. Staging of brain pathology related to sporadic Parkinson’s disease[J]. Neurobiol Aging,2003,24(2):197-211. doi: 10.1016/S0197-4580(02)00065-9
[29]	Lebrun C,G´ely-Nargeot MC,Rossignol A,et al. Efficacy of cognitive behavioral therapy for insomnia comorbid to Parkinson’s disease:a focus on psychological and daytime functioning with a single-case design with multiple baselines[J]. J Clin Psychol,2020,76(3):356-376.
[30]	Alvaro P K,Roberts R M,Harris J K. A Systematic Review Assessing Bidirectionality between Sleep Disturbances,Anxiety,and Depression[J]. Sleep,2013,36(7):1059-1068. doi: 10.5665/sleep.2810

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