The Diagnostic Analysis of Adler Grade of Color Ultrasound for Cervical Cancer and Its Correlation with Pathological Index

Hong PAN; Duwei DENG; Shilin LIU

doi:10.12259/j.issn.2095-610X.S20240517

Volume 45 Issue 5

May 2024

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Hong PAN, Duwei DENG, Shilin LIU. The Diagnostic Analysis of Adler Grade of Color Ultrasound for Cervical Cancer and Its Correlation with Pathological Index[J]. Journal of Kunming Medical University, 2024, 45(5): 109-115. doi: 10.12259/j.issn.2095-610X.S20240517

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Hong PAN, Duwei DENG, Shilin LIU. The Diagnostic Analysis of Adler Grade of Color Ultrasound for Cervical Cancer and Its Correlation with Pathological Index[J]. Journal of Kunming Medical University, 2024, 45(5): 109-115. doi: 10.12259/j.issn.2095-610X.S20240517

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The Diagnostic Analysis of Adler Grade of Color Ultrasound for Cervical Cancer and Its Correlation with Pathological Index

doi: 10.12259/j.issn.2095-610X.S20240517

1.
Dept. of Pathology
2.
Dept. of Ultrasound，Qujing Maternal and Child Health Hospital，Qujing Yunnan 655000，China

Received Date: 2024-01-11
Available Online: 2024-04-26
Publish Date: 2024-05-31

Abstract

Abstract

Objective To investigate the value of Adler grading with color Doppler ultrasound in the diagnosis of cervical cancer, and to analyze its correlation with pathological indexes. Methods 136 patients with cervical cancer in the hospital from January 2020 to January 2023 were retrospectively included as the cervical cancer group, and 80 patients with benign cervical lesions in the hospital during the same period were selected as the control group. All patients received the color Doppler ultrasound examination, and the color Doppler image characteristics and Adler grade were compared between the two groups. Receiver operating characteristic curve （ROC） was plotted to analyze the diagnostic value of color ultrasound in cervical cancer. Cervical cancer group was divided into grade 0 to 1 group and grade 2 to 3 group according to Adler grade. Pathological indexes of grade 0 to 1 group and grade 2 to 3 group were compared to analyze the relationship between the pathological indexes and Adler grade. Results Cervical hyperecho, cervical isoecho, cervical enlargement, Adler grade, PSV, EDV in cervical cancer group were higher than those in the control group, and cervical hypoecho, cervical normal size, RI were lower than those in the control group （P < 0.05）. The ROC curve showed that cervical echo, cervical size, PSV, EDV and RI had the certain diagnostic value for cervical cancer, and Adler grade had the high diagnostic value for cervical cancer （AUC = 0.758, 0.590, 0.902）. The clinical stage, microvascular density, PSV and EDV in grade 2-3 group were higher than those in grade 0-1 group, the maximum lesion diameter was longer than that in grade 0-1 group, and RI was lower than that in grade 0-1 group （P < 0.05）. The Phi coefficient correlation analysis showed that Adler grade was positively correlated with the clinical stage （Phi = 0.203, P = 0.018）. The results showed that Adler grade was positively correlated with the microvascular density, maximum lesion diameter, PSV and EDV （r = 0.664, 0.363, P = 0.000）, and negatively correlated with RI （r = -0.597, P = 0.000）. Conclusion Color ultrasound Adler grading technique has the high diagnostic value in patients with cervical cancer, which is closely related to the clinical stage, microvascular density, maximum lesion diameter and other pathological indicators.
- Cervical cancer,
- Color Doppler ultrasound,
- Adler classification,
- Pathological index

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References(20)

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