Citation: | Shengqiang YANG, Ping WANG. Effect of Hsp90 Inhibitor Ganetespib Combined with Pemetrexed on Lung Adenocarcinoma Cells[J]. Journal of Kunming Medical University, 2024, 45(7): 30-41. doi: 10.12259/j.issn.2095-610X.S20240705 |
[1] |
Lee E,Kazerooni E A. Lung cancer screening[J]. Seminars in Respiratory and Critical Care Medicine,2022,43(6):839-850. doi: 10.1055/s-0042-1757885
|
[2] |
Schabath M B, Cote M L. Cancer progress and priorities: Lung cancer [J]. Cancer Epidemiology, Biomarkers & Prevention, 2019, 28(10): 1563-1579.
Schabath M B,Cote M L. Cancer progress and priorities: Lung cancer [J]. Cancer Epidemiology,Biomarkers & Prevention,2019,28(10): 1563-1579.
|
[3] |
Sung H,Ferlay J,Siegel R L,et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer Journal for Clinicians,2021,71(3):209-249. doi: 10.3322/caac.21660
|
[4] |
Goss P E,Strasser-weippl K,Lee-bychkovsky B L,et al. Challenges to effective cancer control in China,India,and Russia[J]. Lancet Oncology,2014,15(5):489-538. doi: 10.1016/S1470-2045(14)70029-4
|
[5] |
Ruiz-cordero R,Devine W P. Targeted therapy and checkpoint immunotherapy in lung cancer[J]. Surgical Pathology Clinics,2020,13(1):17-33. doi: 10.1016/j.path.2019.11.002
|
[6] |
Chaft J E,Shyr Y,Sepesi B,et al. Preoperative and postoperative systemic therapy for operable non-small-cell lung cancer[J]. Journal of Clinical Oncology,2022,40(6):546-555. doi: 10.1200/JCO.21.01589
|
[7] |
Yousefi M,Bahrami T,Salmaninejad A,et al. Lung cancer-associated brain metastasis: Molecular mechanisms and therapeutic options[J]. Cellular Oncology (Dordrecht),2017,40(5):419-441. doi: 10.1007/s13402-017-0345-5
|
[8] |
Yousefi M E,Cavalu S,Hasan A M,et al. Role of ganetespib,An HSP90 inhibitor,in cancer therapy: From molecular mechanisms to clinical practice[J]. International Journal of Molecular Sciences,2023,24(5):.5014 doi: 10.3390/ijms24055014
|
[9] |
Birbo B,Madu E E,Madu C O,et al. Role of HSP90 in cancer[J]. International Journal of Molecular Sciences,2021,22(19):.10317 doi: 10.3390/ijms221910317
|
[10] |
Stivarou T,Patsavoudi E. Extracellular molecules involved in cancer cell invasion[J]. Cancers,2015,7(1):238-265. doi: 10.3390/cancers7010238
|
[11] |
Proia D A,Foley K P,Korbut T,et al. Multifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signaling[J]. PloS One,2011,6(4):e18552. doi: 10.1371/journal.pone.0018552
|
[12] |
Xiang L,Gilkes D M,Chaturvesi P,et al. Ganetespib blocks HIF-1 activity and inhibits tumor growth,vascularization,stem cell maintenance,invasion,and metastasis in orthotopic mouse models of triple-negative breast cancer[J]. Journal of Molecular Medicine (Berlin,Germany),2014,92(2):151-164. doi: 10.1007/s00109-013-1102-5
|
[13] |
Gadgeel S,Rodriguez-abreu D,Speranza G,et al. Updated analysis from KEYNOTE-189: Pembrolizumab or placebo plus pemetrexed and platinum for previously untreated metastatic nonsquamous non-small-cell lung cancer[J]. Journal of Clinical Oncology,2020,38(14):1505-1517. doi: 10.1200/JCO.19.03136
|
[14] |
Zhang J,Song C,Tian Y,et al. Single-cell RNA sequencing in lung cancer: Revealing phenotype shaping of stromal cells in the microenvironment[J]. Frontiers in Iimmunology,2021,12:802080.
|
[15] |
Hirsch F R,Scagliotti G V,Mulshine J L,et al. Lung cancer: current therapies and new targeted treatments[J]. Lancet,2017,389(10066):299-311. doi: 10.1016/S0140-6736(16)30958-8
|
[16] |
Park S,Keam B,Kim S H,et al. Pemetrexed singlet versus nonpemetrexed-based platinum doublet as second-line chemotherapy after first-line epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor failure in non-small cell lung cancer patients with EGFR mutations[J]. Cancer Research and Treatment,2015,47(4):630-637. doi: 10.4143/crt.2014.244
|
[17] |
Jones G S,Baldwin D R. Recent advances in the management of lung cancer[J]. Clinical Medicine (London,England),2018,18(Suppl 2):s41-s46.
|
[18] |
Yoshimura N,Okishio K,Mitsuoka S,et al. Prospective assessment of continuation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of pemetrexed[J]. Journal of Thoracic Oncology,2013,8(1):96-101. doi: 10.1097/JTO.0b013e3182762bfb
|
[19] |
Fuld A D,Dragnev K H,Rigas J R. Pemetrexed in advanced non-small-cell lung cancer[J]. Expert Opinion on Pharmacotherapy,2010,11(8):1387-1402. doi: 10.1517/14656566.2010.482560
|
[20] |
Wu S G,Yang C H,Yu C J,et al. Good response to pemetrexed in patients of lung adenocarcinoma with epidermal growth factor receptor (EGFR) mutations[J]. Lung Cancer,2011,72(3):333-339. doi: 10.1016/j.lungcan.2010.10.012
|
[21] |
Cui J,Zhang Y,Su D,et al. Efficacy of combined icotinib and pemetrexed in EGFR mutant lung adenocarcinoma cell line xenografts[J]. Thoracic Cancer,2018,9(9):1156-1165. doi: 10.1111/1759-7714.12818
|
[22] |
Feng X,Zhang Y,Li T,et al. Sequentially administrated of pemetrexed with icotinib/erlotinib in lung adenocarcinoma cell lines in vitro[J]. Oncotarget,2017,8(69):114292-114299. doi: 10.18632/oncotarget.23224
|
[23] |
Noronha V,Patil V M,Joshi A,et al. Gefitinib versus gefitinib plus pemetrexed and carboplatin chemotherapy in EGFR-mutated lung cancer[J]. Journal of Clinical Oncology,2020,38(2):124-136. doi: 10.1200/JCO.19.01154
|
[24] |
Taipale M,Jarosz D F,Lindquist S. HSP90 at the hub of protein homeostasis: Emerging mechanistic insights[J]. Nature Reviews Molecular Cell Biology,2010,11(7):515-528. doi: 10.1038/nrm2918
|
[25] |
Shimamura T,Li D,JI H,et al. Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance[J]. Cancer Research,2008,68(14):5827-5838. doi: 10.1158/0008-5472.CAN-07-5428
|
[26] |
Acquaviva J,Smith D L,Sang J,et al. Targeting KRAS-mutant non-small cell lung cancer with the Hsp90 inhibitor ganetespib[J]. Molecular Cancer Therapeutics,2012,11(12):2633-2643. doi: 10.1158/1535-7163.MCT-12-0615
|
[27] |
Sequist L V,Gettinger S,Senzer N N,et al. Activity of IPI-504,a novel heat-shock protein 90 inhibitor,in patients with molecularly defined non-small-cell lung cancer[J]. Journal of Clinical Oncology,2010,28(33):4953-4960. doi: 10.1200/JCO.2010.30.8338
|
[28] |
Neckers L,Workman P. Hsp90 molecular chaperone inhibitors: Are we there yet?[J]. Clinical Cancer Research,2012,18(1):64-76. doi: 10.1158/1078-0432.CCR-11-1000
|
[29] |
Proia D A,Sang J,HE S,et al. Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models[J]. Investigational New Drugs,2012,30(6):2201-2209. doi: 10.1007/s10637-011-9790-6
|
[30] |
Smith D L,Acquaviva J,Sequeira M,et al. The HSP90 inhibitor ganetespib potentiates the antitumor activity of EGFR tyrosine kinase inhibition in mutant and wild-type non-small cell lung cancer[J]. Targeted Oncology,2015,10(2):235-245. doi: 10.1007/s11523-014-0329-6
|
[31] |
Fennell D A,Danson S,Woll P J,et al. Ganetespib in combination with pemetrexed-platinum chemotherapy in patients with pleural mesothelioma (MESO-02): A phase Ib trial[J]. Clinical Cancer Research,2020,26(18):4748-4755. doi: 10.1158/1078-0432.CCR-20-1306
|
[32] |
Stecklein S R,Kumaraswamy E,Behbod F,et al. BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation[J]. Proceedings of the National Academy of Sciences of the United States of America,2012,109(34):13650-13655.
|
[33] |
Abu Lila A S,Kato C,Fukshima M,et al. Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model[J]. International Journal of Oncology,2016,48(4):1399-1407. doi: 10.3892/ijo.2016.3367
|
[34] |
Zucali P A,Giovannetti E,Destro A,et al. Thymidylate synthase and excision repair cross-complementing group-1 as predictors of responsiveness in mesothelioma patients treated with pemetrexed/carboplatin[J]. Clinical Cancer Research,2011,17(8):2581-2590. doi: 10.1158/1078-0432.CCR-10-2873
|
[35] |
Deng Z,Qin Y,Liu Y,et al. Role of antiangiogenic agents combined with EGFR tyrosine kinase inhibitors in treatment-naive lung cancer: A meta-analysis[J]. Clinical Lung Cancer,2021,22(1):e70-e83. doi: 10.1016/j.cllc.2020.08.005
|
[36] |
Xue J,Li B,Wang Y,et al. Efficacy and safety of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor combination therapy as first-line treatment for patients with advanced EGFR-mutated,non-small cell lung cancer: A systematic review and bayesian network meta-analysis[J]. Cancers,2022,14(19):4894. doi: 10.3390/cancers14194894
|
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