Analysis of Relevant Indicators for Acute Traumatic Head Injury Upon Immediate Admission

Xiaogai NIE; Yunfang ZHANG; Shanshan ZHUANG; Kun TU; Jiao WANG

doi:10.12259/j.issn.2095-610X.S20240919

Volume 45 Issue 9

Sep. 2024

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Article Navigation > Journal of Kunming Medical University > 2024 > 45(9): 122-128

Xiaogai NIE, Yunfang ZHANG, Shanshan ZHUANG, Kun TU, Jiao WANG. Analysis of Relevant Indicators for Acute Traumatic Head Injury Upon Immediate Admission[J]. Journal of Kunming Medical University, 2024, 45(9): 122-128. doi: 10.12259/j.issn.2095-610X.S20240919

Citation:

Xiaogai NIE, Yunfang ZHANG, Shanshan ZHUANG, Kun TU, Jiao WANG. Analysis of Relevant Indicators for Acute Traumatic Head Injury Upon Immediate Admission[J]. Journal of Kunming Medical University, 2024, 45(9): 122-128. doi: 10.12259/j.issn.2095-610X.S20240919

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Analysis of Relevant Indicators for Acute Traumatic Head Injury Upon Immediate Admission

doi: 10.12259/j.issn.2095-610X.S20240919

1.
Dept. of Medical Laboratory
2.
Dept. of Neurology，Yan’an Hospital of Kunming，Kunming Yunnan 650051，China

Received Date: 2024-03-04
Available Online: 2024-09-04
Publish Date: 2024-09-25

Abstract

Abstract

Objective To explore the test indicators closely related to the incidence and prognosis of acute traumatic head injury. Methods The data of 156 patients with head injuries admitted to the emergency department from October 2022 to June 2023 after the establishment of the trauma center of Yan'an Hospital of Kunming were collected. The gender, age, prognosis, and laboratory tests immediately after admission were statistically analyzed. Results The incidence rate of acute TBI patients was significantly higher in males than in females, with a ratio of 2.62∶1, and the incidence of moderate to severe and poor prognosis was significantly higher in males than females, and the difference was statistically significant P < 0.05. The main age of onset was 39～72 years old, and the age of patients with poor prognosis was significantly higher than that of patients with good prognosis, and the difference was statistically significant, P < 0.05. The tests immediately upon admission WBC, CRPH, AST, GLU, D-Dimers, S100βand IL-6 in the patients with craniocerebral injury were significantly higher than those in the normal control group, and the recombinant WBC, CRPH and AST were higher than those in the mild group. The levels of CRPH, AST and GLU in the poor prognosis group were higher than those in the good prognosis group, and the difference was statistically significant P < 0.05. Conclusion Immediate test markers, such as WBC, CRPH, AST, GU, etc., may be related to the severity or poor prognosis of acute traumatic head injury, and clinicians should pay attention to and timely targeted intervention and treatment to improve adverse outcomes.
- Traumatic head injury,
- Trauma centers,
- Prognosis

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References(23)

References

[1]	刘华,李兵,阮海林,等. 急性创伤住院患者的流行病学特征[J]. 山东医药,2014,54(43):19-21.
[2]	王正国. 创伤研究进展[J]. 中华急诊医学杂志,2012,21(6):565-567.
[3]	GBD 2017 Causes of Death Collaborators. Global,regional,and national age-sex-specific mortality for 282 causes of death in 195 countries and territories,1980-2017: A systematic analysis for the global burden of disease study 2017[J]. Lancet,2018,392(10159):1736-1788. doi: 10.1016/S0140-6736(18)32203-7
[4]	Nielsen K,Mock C,Joshipura M,et al. Assessment of the status of prehospital care in 13 low- and middle-income countries[J]. Prehosp Emerg Care,2012,16(3):381-389. doi: 10.3109/10903127.2012.664245
[5]	Brown J B,Rosengart M R,Forsythe R M,et al. Not all prehospital time is equal: Influence of scene time on mortality[J]. J Trauma A-cute Care Surg,2016,81(1):93-100. doi: 10.1097/TA.0000000000000999
[6]	GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators. Global,regional,and national burden of traumatic brain injury and spinal cord injury,1990- 2016: A systematic analysis for the Global Burden of Disease Study 2016[J]. Lancet Neurol,2019,18(1):56-87. doi: 10.1016/S1474-4422(18)30415-0
[7]	苏达昌. CT检查在急性颅脑损伤诊断中的应用价值[J]. 影像研究与医学应用,2022,6(14):107-109.
[8]	陈孝平,汪建平,赵继宗. 外科学[M]. 9版. 北京:人民卫生出版社, 2018: 184-197.
[9]	Chun M,Zhang Y,Becnel C,et al. New injury severity score and trauma injury severity score are superior in predicting trauma mortality[J]. J Trauma Acute Care Surg,2022,92(3):528-534. doi: 10.1097/TA.0000000000003449
[10]	McMillan T,Wilson L,Ponsford J,et al. The glasgow outcome scale - 40 years of application and refinement[J]. Nat Rev Neurol,2016,12(8):477-485. doi: 10.1038/nrneurol.2016.89
[11]	蒋鸿雁,杨凤,曹艳,等. 2004-2013年昆明医科大学第一附属医院创伤性脑损伤流行病学特征调查[J]. 昆明医科大学学报,2022,43(4):12-18.
[12]	Vella M A,Crandall M L,Patel M B. Acute management of traumatic brain injury[J]. Surg Clin North Am,2017,97(5):1015-1030. doi: 10.1016/j.suc.2017.06.003
[13]	商崇智,涂悦,彭定伟,等. 急性创伤性脑损伤超早期白细胞计数变化及其临床意义[J]. 中华创伤杂志,2016,32(6):502-505.
[14]	相毅,孙昭胜. C-反应蛋白与急性创伤性颅脑损伤[J]. 中国医师进修杂志,2008,31(9):67-69.
[15]	姚士伟,吴静,崔培林. 创伤性颅脑损伤后肝功能变化的探讨[J]. 中国误诊学杂志,2009,9(12):2851-2852.
[16]	周铁成,秦庆,杨小云,等. 脑脊液CPK,LDH,AST,α-HBD和ALT对中枢神经系统疾病的诊断意义[J]. 第四军医大学学报,2003,24(23):2154-2156.
[17]	杨巧云,刘文明,周仪,等. 血糖波动对重型创伤性颅脑损伤患者预后的影响[J]. 中国急救医学,2017,37(7):612-616.
[18]	罗才奎, 孟亮, 王跃飞, 等. 急性重型颅脑损伤患者血糖水平对预后的影响[J]. 中华内分泌外科杂志,2018,12(4):318-321.
[19]	李苹,王隆庆,杨晶晶,等. 颅脑损伤患者急性期凝血功能指标及D-二聚体变化的临床分析[J]. 宁夏医学杂志,2019,41(7):610-613.
[20]	陈思颖,伍国达,何春柳. 颅脑损伤急性期凝血常规及D-二聚体变化的临床观察[J]. 临床医学工程,2017,24(1):105-106.
[21]	张雅旋,郭瑞娟,张寅,等. 外周血S100钙结合蛋白、Hcy及神经元特异性烯醇化酶水平与创伤性颅脑损伤患者颅内血肿吸收情况及认知功能的相关性分析[J]. 南京医科大学学报(自然科学版),2022,42(10):1421-1425.
[22]	王伟,张其俊. 急诊早期创伤性颅脑损伤患者血清VEGF、S100β水平与疾病严重程度及预后的关系分析[J]. 浙江创伤外科,2023,28(8):1560-1562.
[23]	王英,廖英. 血清S100B、IL-1β、IL-6水平与颅脑损伤患者损伤程度和预后的相关性研究[J]. 川北医学院学报,2021,36(10):1352-1354,1394. doi: 10.3969/j.issn.1005-3697.2021.10.020

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