Analysis of Correlation between Blood Biochemical Indexes and Blood Pressure Level among College Students in Kunming City

Feifei DENG; Wei WANG; Qiuan LU; Na LIU; Zhen XU; Honglv XU

doi:10.12259/j.issn.2095-610X.S20250213

Volume 46 Issue 2

Feb. 2025

Turn off MathJax

Article Contents

Abstract

References

Relative Articles

Article Navigation > Journal of Kunming Medical University > 2025 > 46(2): 88-94

Feifei DENG, Wei WANG, Qiuan LU, Na LIU, Zhen XU, Honglv XU. Analysis of Correlation between Blood Biochemical Indexes and Blood Pressure Level among College Students in Kunming City[J]. Journal of Kunming Medical University, 2025, 46(2): 88-94. doi: 10.12259/j.issn.2095-610X.S20250213

Citation:

Feifei DENG, Wei WANG, Qiuan LU, Na LIU, Zhen XU, Honglv XU. Analysis of Correlation between Blood Biochemical Indexes and Blood Pressure Level among College Students in Kunming City[J]. Journal of Kunming Medical University, 2025, 46(2): 88-94. doi: 10.12259/j.issn.2095-610X.S20250213

Citation:

Feifei DENG, Wei WANG, Qiuan LU, Na LIU, Zhen XU, Honglv XU. Analysis of Correlation between Blood Biochemical Indexes and Blood Pressure Level among College Students in Kunming City[J]. Journal of Kunming Medical University, 2025, 46(2): 88-94. doi: 10.12259/j.issn.2095-610X.S20250213

PDF( 599 KB)

Analysis of Correlation between Blood Biochemical Indexes and Blood Pressure Level among College Students in Kunming City

doi: 10.12259/j.issn.2095-610X.S20250213

Feifei DENG^{1, 2
,
,},
Wei WANG³,
Qiuan LU^{1, 2},
Na LIU^{1, 2},
Zhen XU^{1, 2},
Honglv XU^{1, 2}

1.
Medical College
2.
Community Nursing Research Team，Kunming University，Kunming Yunnan 650214
3.
Department of Emergency，The Second Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China

Received Date: 2024-04-26
Available Online: 2025-01-05
Publish Date: 2025-02-18

Abstract

Abstract

Objective To explore the correlation between blood biochemical indexes and blood pressure levels among college students in Kunming City. Methods In November 2021, a cluster sampling method was used to survey 4,781 college students at a university in Yunnan Province. Data collected included height, weight and blood pressure, and blood samples were collected for blood biochemical testing. The Mann-Whitney U test and Kruskal-Wallis H test were used to compare the distribution differences of hypertension among college students with different demographic characteristics, while a generalized linear model was used to analyze the correlation between blood biochemical indicators and blood pressure levels. Results The prevalence rate of hypertension among college students was 8.45% （404/4781）. After adjusting confounding variables, blood glucose （GLU, β = 1.48, 95%CI : 0.75～2.20） and serum Total Protein （TP, β = 0.25 , 95%CI : 0.19～0.32） were found to be correlated with systolic blood pressure （SBP） levels （all P < 0.05）; blood glucose （GLU, β = 1.25, 95%CI : 0.64～1.86） and serum total protein （TP, β = 0.28, 95%CI : 0.23～0.34） were correlated with diastolic blood pressure （DBP） level （P < 0.05）. Stratified group analysis by sex showed that, after controlling for confounding factors, TP （β = 0.32, 95%CI : 0.18～0.45） was correlated with SBP levels in male students; TP （β = 0.32, 95%CI : 0.21～0.43） was correlated with DBP levels in male students （P < 0.05）. GLU （β = 2.18, 95%CI : 1.29～3.07） and TP （β = 0.23, 95%CI : 0.15～0.31） were correlated with SBP levels in female students; GLU （β = 1.48, 95%CI : 0.73～2.24） and TP （β = 0.26, 95%CI : 0.20～0.33） were correlated with DBP levels in female students （all P < 0.05）. Conclusion Our findings suggest that blood glucose and serum total protein level are correlated with blood pressure levels in female college students, while serum total protein level are correlated with blood pressure levels in male college students.
- Hypertension,
- College students,
- Blood biochemistry,
- Correlation analysis

FullText(HTML)

References(19)

References

[1]	Zhou B,Perel P,Mensah G A,et al. Global epidemiology,health burden and effective interventions for elevated blood pressure and hypertension[J]. Nat Rev Cardiol,2021,18(11):785-802. doi: 10.1038/s41569-021-00559-8
[2]	Bao M,Wang L. The longitudinal trend of hypertension prevalence in Chinese adults from 1959 to 2018: A systematic review and meta-analysis[J]. Ann Palliat Med,2020,9(5):2485-2497. doi: 10.21037/apm-19-377
[3]	Jiang Q,Zhang Q,Wang T,et al. Prevalence and risk factors of hypertension among college freshmen in China[J]. Sci Rep,2021,11(1):1-8. doi: 10.1038/s41598-020-79139-8
[4]	Zhang Z,Li M,Li J,et al. Meta-analysis and time trend prediction of the prevalence of hypertension in Chinese college students[J]. Medicine (Baltimore),2023,102(42):1-11.
[5]	Mansouri M,Sharifi F,Yaghubi H,et al. Sugar-sweetened beverages consumption in relation to hypertension among Iranian university students: the MEPHASOUS study[J]. Eat Weight Disord,2020,25(4):973-982. doi: 10.1007/s40519-019-00713-9
[6]	Vo H K,Nguyen D V,Vu T T,etal. Prevalence and risk factors of prehypertension/hypertension among freshman students from the Vietnam National University: A cross-sectional study[J]. BMC Public Health,2023,23(1):1-9. doi: 10.1186/s12889-022-14670-z
[7]	郭文彬. 体检人群中高血压与临床指标相关性分析[J]. 中西医结合心血管病电子杂志,2022,10(21):50-52.
[8]	Xu H,Sun Y,Wan Y,et al. Eating pattern and psychological symptoms: A cross-sectional study based on a national large sample of Chinese adolescents[J]. J Affect Disord,2019,244(2):155-163.
[9]	中华人民教育部. 国家学生体质健康标准(2014年修订)[EB/OL](2014-07-07)[2025-01-09]. http://www.moe. Gov.cn/s78/A17/twys_left/moe_938/moe_792/s3273/201407/t20140708_171692.html.
[10]	林洋, 冉擘力. 《中国高血压防治指南(2024年修订版)》更新要点解读[J]. 现代医药卫生,2024,40(24):4141-4144.
[11]	郎俊杰,金来润,刘凌,等. 中国大学生高血压患病率的Meta分析[J]. 中国学校卫生,2018,39(8):1220-1223.
[12]	杨玲芳,秦伟,吴煜聊. 阜阳市某高校大学生高血压患病现状及与体质量指数相关性分析[J]. 安徽预防医学杂志,2018,24(2):91-94.
[13]	张慧. 某高校大学新生高血压调查分析[J]. 中国校医,2022,36(10):797-799.
[14]	Gerdts E,Sudano I,Brouwers S,et al. Sex differences in arterial hypertension[J]. Eur Heart J,2022,43(46):4777-4788. doi: 10.1093/eurheartj/ehac470
[15]	Manolis A A,Manolis T A,Melita H,et al. Low serum albumin: A neglected predictor in patients with cardiovascular disease[J]. Eur J Intern Med,2022,102(2):24-39.
[16]	Rabbani G,Ahn S N. Structure,enzymatic activities,glycation and therapeutic potential of human serum albumin: A natural cargo[J]. Int J Biol Macromol,2019,123(2):979-990.
[17]	Snipelisky D,Jentzer J,Batal O,et al. Serum albumin concentration as an independent prognostic indicator in patients with pulmonary arterial hypertension[J]. Clin Cardiol,2018,41(6):782-787. doi: 10.1002/clc.22954
[18]	张宸溪,曹竹君,项晓刚,等. 人血清白蛋白治疗失代偿期肝硬化的研究进展[J]. 上海交通大学学报(医学版),2023,43(1):95-100.
[19]	Jia G,Sowers J R. Hypertension in diabetes: An update of basic mechanisms and clinical disease[J]. Hypertension,2021,78(5):1197-1205. doi: 10.1161/HYPERTENSIONAHA.121.17981

Relative Articles(20)

Relative Articles

[1]	Da PENG, Aijun ZHANG. The Relationship between Urinary NGAL and Flow-mediated Vasodilation in Prehypertension. Journal of Kunming Medical University, 2024, 45(1): 127-132. doi: 10.12259/j.issn.2095-610X.S20240121
[2]	You HUANG, Guohui LI, Duli LIU, Zizi YU, Mei ZUO, Qin LI, Bo LYU, Le CAI. Prevalence of Hypertension and Its Relationship with Clustering of Risk Factors of Cardiovascular Diseases in The Elderly of Han Majority and Ha Ni Ethnic Minority in Rural District of Mojiang County of Yunnan Province. Journal of Kunming Medical University, 2024, 45(9): 42-48. doi: 10.12259/j.issn.2095-610X.S20240907
[3]	Yunjuan YANG, Yuanyi ZHA, Tunan LI. Comparison of Two Diagnosis Standards for Evaluating Hypertension in 18 Years Old Students in Yunnan China. Journal of Kunming Medical University, 2023, 44(3): 44-48. doi: 10.12259/j.issn.2095-610X.S20230324
[4]	Yunjuan YANG, Tao MA, Yuanyi ZHA, Litao CHANG, Hong LIU, Fan YANG, Limei DAI, Fang LI. Epidemic Trends and Characteristics of Hypertension among Primary and Secondary Students from 2017 to 2020 in Kunming，Yunnan. Journal of Kunming Medical University, 2022, 43(11): 17-21. doi: 10.12259/j.issn.2095-610X.S20221104
[5]	Zhao Xiao Li , Yue Wei Wei , Miao Wen Qing , Qian Jing , Zhu Dan , Li Sui Wen , Yang Yue Lin , Li Hai Sheng , Hu Da Chun . . Journal of Kunming Medical University, 2020, 41(07): 76-79.
[6]	Wang Hua Wei , Meng Zhao Hui , Lu Ya Nan , Huang Zhao , Xu Jun , Chen Li Xing . . Journal of Kunming Medical University, 2020, 41(01): 42-47.
[7]	Ding Si Pin , Wang Ling , Bao Lei , Chen Yue Yue , Wang Ken Jun , Dong Zheng Jiao , Zhang Jing Jing . . Journal of Kunming Medical University, 2020, 41(02): 26-31.
[8]	Sun Cheng Huan , Zhou Jia , Mao Yong , Luo Jia Hong , Chu Tian Shu , Lai Chun Mi , Qi Bing Xian , Zhang Qing . The Awareness, Treatment and Control of Hypertension and Its Determinants in the Elderly Hypertensive Patients of Dean Nationality: A Multilevel Model Analysis. Journal of Kunming Medical University, 2018, 39(01): 39-44.
[9]	Dong Ling , Peng Yun Zhu , Huang Cheng , Huang Zhao , Chen Li Xing . Prevalence Rate and Associated Risk Factors of Hypertension in Bai Ethnic Group in Yunnan. Journal of Kunming Medical University, 2018, 39(07): 52-57.
[10]	Bao Wen Li . Effects of Yoga on Physical Function Quality of College Students. Journal of Kunming Medical University,
[11]	Li Hui . Correlation Analysis between Prenatal Infection and Premature Rupture of Membranes. Journal of Kunming Medical University,
[12]	Liu Xiao Chen . A Survey of Allergic Rhinitis among College Students in Kunming. Journal of Kunming Medical University,
[13]	Li Wen Hong . . Journal of Kunming Medical University,
[14]	Zhao Jiang . . Journal of Kunming Medical University,
[15]	Li Hong Fei . . Journal of Kunming Medical University,
[16]	Du Ying Rong . . Journal of Kunming Medical University,
[17]	Pang Xing Mei . . Journal of Kunming Medical University,
[18]	Guo Xue Mei . . Journal of Kunming Medical University,
[19]	Zhang Ren Fa . . Journal of Kunming Medical University,
[20]	Zhang Dan Xia . . Journal of Kunming Medical University,