Role of MAPKs in Protection of Hydrogen Sulfide against Lung Injury Following Limb Ischemia-reperfusion in Rats

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Role of MAPKs in Protection of Hydrogen Sulfide against Lung Injury Following Limb Ischemia-reperfusion in Rats[J]. Journal of Kunming Medical University, 2011, 32(09).

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Role of MAPKs in Protection of Hydrogen Sulfide against Lung Injury Following Limb Ischemia-reperfusion in Rats[J]. Journal of Kunming Medical University, 2011, 32(09).

Role of MAPKs in Protection of Hydrogen Sulfide against Lung Injury Following Limb Ischemia-reperfusion in Rats[J]. Journal of Kunming Medical University, 2011, 32(09).

Citation:

Role of MAPKs in Protection of Hydrogen Sulfide against Lung Injury Following Limb Ischemia-reperfusion in Rats[J]. Journal of Kunming Medical University, 2011, 32(09).

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Role of MAPKs in Protection of Hydrogen Sulfide against Lung Injury Following Limb Ischemia-reperfusion in Rats

Abstract

Abstract

Objective To observe the role of mitogen-activated protein kinases(MAPKs)in protection of exogenous hydrogen sulfide(H2S)against lung injury induced by ischemia-reperfusion(IR)of hind limbs in rats.Methods A rat model of limb ischemia was made by tourniquets placed on both hind limbs at a site proximal to trochanter major and the lung injury was induced following reperfusion.Adult male Spraguce-Dawley(SD)rats were randomly divided into four groups(n=8 per group):Control,Control+NaHS,IR and IR+ NaHS.The rats...
- Mitogen-activated protein kinase,
- Hydrogen sulfide,
- Reperfusion injury,
- Limbs,
- Lung

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