Azasetron for Prophylaxis of Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy in Female Patients at Menstrual Phase

Qu Qi Cai

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Qu Qi Cai . Azasetron for Prophylaxis of Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy in Female Patients at Menstrual Phase[J]. Journal of Kunming Medical University, 2016, 37(03).

Citation:

Qu Qi Cai . Azasetron for Prophylaxis of Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy in Female Patients at Menstrual Phase[J]. Journal of Kunming Medical University, 2016, 37(03).

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Azasetron for Prophylaxis of Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy in Female Patients at Menstrual Phase

Qu Qi Cai

(Dept. of Anesthesiology,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650101,China)

Abstract

Abstract

［Abstract］Objective To investigate the preventive effects of azasetron against postoperative nausea and vomiting（PONV）after laparoscopic cholecystectomy in female patients at menstrual phase. Methods　Forty ASA Ⅰ or Ⅱ female patients at menstrual phase were randomly divided into azasetron group（n＝20）and control group （n＝20）. Induction and maintenance of anesthesia was routine. Azasetron 10mg or normal saline 50 ml was given at 30 min before the end of surgery. The incidence and intensity of PONV was recorded during 48 hours after surgery. Results Compare to the control group, the incidence of PONV was lower at 48 hour after surgery in azasetron group （35% vs 90%，P < 0.01），and the incidence of PONV in Ⅳ level was also lower in azasetron group（P < 0.05）. Conclusion Azasetron can decrease the incidence and intensity of PONV after laparoscopic cholecystectomy during menstrual phase.
- ［Key words］Azasetron；Postoperative nausea and vomiting；Female；Menstruation；Laparoscopic cholecystectomy,

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