Xie Yuan Run . Experimental Study on The Chemotaxis of Blood Monocyte to Three Kinds of Glioma Cell Lines(U87,U251 and T98G) in Vitro[J]. Journal of Kunming Medical University, 2016, 37(04).
Citation: Xie Yuan Run . Experimental Study on The Chemotaxis of Blood Monocyte to Three Kinds of Glioma Cell Lines(U87,U251 and T98G) in Vitro[J]. Journal of Kunming Medical University, 2016, 37(04).

Experimental Study on The Chemotaxis of Blood Monocyte to Three Kinds of Glioma Cell Lines(U87,U251 and T98G) in Vitro

  • [Abstract]Objective To observe the chemotaxis of blood monocyte to three kinds of glioma cell lines(U87,U251 and T98G),and discuss the source of tumor associated macrophages in glioma and its clinicopathologic significance. Method Transwell assay was applied to observe the chemotaxis of blood monocyte to three kinds of glioma cell lines(U87,U251 and T98G). Results The chemotaxis of blood monocyte to the three kinds of glioma cell lines(U87,U251 and T98G)was higher than that in the control group(P<0.01). The chemotaxis of blood monocyte to U87 was higher than that of U251 and T98G(P=0.001). The chemotaxis of blood monocyte to U251 was higher than that of T98G(P=0.03). Conclusion The three kinds of glioma cell lines all have the ability to chemoattract blood monocyte, suggesting that blood monocytes are one of the important sources of glioma associated macrophages,and play an important role in the occurrence or development of the glioma.
  • loading
  • Relative Articles

    [1] Zhenxiao ZHANG, Jingjing ZHANG, Yun LIAO, Dandan LI, Heng LI, Longding LIU. Effects of HSV-1 Mutant Strain M6 on Macrophage-Mediated Immune Response after Infecting Human Bronchial Epithelial Cells. Journal of Kunming Medical University, 2024, 45(7): 6-13.  doi: 10.12259/j.issn.2095-610X.S20240702
    [2] Haopeng SHENTU, Jing YANG, WeiQing GE, Tao ZHOU, En SONG. Macrophage Polarization and Thrombotic Diseases. Journal of Kunming Medical University, 2024, 46(): 1-8.
    [3] Liang ZHANG, Baoquan WANG, Xifeng LEI, Xu WANG, Yang KE, Wei ZHANG. M2 Macrophage-derived Exosome miR-1246 Regulates the Growth and Invasion of Gastric Cancer Cells. Journal of Kunming Medical University, 2023, 44(7): 69-77.  doi: 10.12259/j.issn.2095-610X.S20230724
    [4] Yanlong LIU, Xuefeng GUANG, Xiaolong YIN, Hailong DAI. Effects of miR-125a-3p on Atherosclerotic Plaque, M1/M2 Macrophages, MMP-9 and VEGF. Journal of Kunming Medical University, 2022, 43(9): 1-6.  doi: 10.12259/j.issn.2095-610X.S20220915
    [5] Weijia ZHAO, Hongbin LI, Zonghan CHEN. Effects of Micafungin on the Activity of Candida Smooth in Macrophages. Journal of Kunming Medical University, 2022, 43(1): 14-19.  doi: 10.12259/j.issn.2095-610X.S20220142
    [6] Xiao CAI, Xue-tao YI, Jing-qing YAO, Xin-yu DAI, Zhong-quan TANG, Ting OU, Xiao-min ZHAO, Yun-tao LI. The Regulation of Exosome Derived from Human Bone Marrow Mesenchymal Stem Cells on the Polarization of Glioma-associated Macrophages. Journal of Kunming Medical University, 2021, 42(1): 38-45.  doi: 10.12259/j.issn.2095-610X.S20210101
    [7] Dai Hai Long , Zhang Xing , Pan Yun , Feng Xiao Lan , Lu Xiang Ting , Guang Xue Feng , Yin Xiao Long . . Journal of Kunming Medical University, 2020, 41(04): 60-63.
    [8] Chen Xian Wei , Lu Xiang Dong , Wang Yong Feng , Zhao Die Bo , Yang Xu , Wang Wen Xuan , Fan Yan Xin , Zhang Hui , Zhao Bin . . Journal of Kunming Medical University, 2019, 40(06): 76-79.
    [9] Yang Rong , Yang Ying . . Journal of Kunming Medical University, 2017, 38(05): 44-49.
    [10] Zhang Xiao Chao , Shen Zhi Qiang , Yang Ren Hua , Tang Chuan Jing , Bai Lin Ying , He Bo , Chen Peng , Yao Rong Cheng . Effects of Corilagin on Expression of CRP in OX-LDL Injured Macrophage Cells. Journal of Kunming Medical University, 2017, 38(08): 1-5.
    [11] Dong Zhong Li . Monocytes/Macrophages Promote Venous Thrombosis Organization and Recanalization:Mechanism and Research Progress. Journal of Kunming Medical University,
    [12] He Feng Die . The Changes of Serum CRP, IL-2, MCP-1 and Hemorheology of Patients with Pelvic Inflammatory Disease. Journal of Kunming Medical University,
    [13] Du Kai . . Journal of Kunming Medical University,
    [14] Li Fan. . Journal of Kunming Medical University,
    [15] Shi Zhao Kun . . Journal of Kunming Medical University,
    [16] Wang Shao Yun . . Journal of Kunming Medical University,
    [17] Li Xiao Ting . . Journal of Kunming Medical University,
    [18] . Study on the Expression of CD45RO+ and CD45RA+T Lymphocytes in Peripheral Blood of Children Patients with Infectious Mononucleosis. Journal of Kunming Medical University,
    [19] Cao Jia . Hp Infection and HLA-DR Antigen Expression in Peripheral Blood Lymphocytes and Monocytes among Family Members of Children with Recurrent Abdominal Pain. Journal of Kunming Medical University,
    [20] Yao Jin . . Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2679) PDF downloads(287) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return