Correlation of 5-HT Transporter Protein Gene (SLC6A4) Polymorphism and Conduct Disorder in Children

Lin Yan; Zhang Jing Jing; Huang Gao Gui; Zhang Yi Yu; Rui Li; Yao Shu Xiang

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Lin Yan , Zhang Jing Jing , Huang Gao Gui , Zhang Yi Yu , Rui Li , Yao Shu Xiang . Correlation of 5-HT Transporter Protein Gene (SLC6A4) Polymorphism and Conduct Disorder in Children[J]. Journal of Kunming Medical University, 2017, 38(04): 28-31.

Citation:

Lin Yan , Zhang Jing Jing , Huang Gao Gui , Zhang Yi Yu , Rui Li , Yao Shu Xiang . Correlation of 5-HT Transporter Protein Gene (SLC6A4) Polymorphism and Conduct Disorder in Children[J]. Journal of Kunming Medical University, 2017, 38(04): 28-31.

Citation:

Lin Yan , Zhang Jing Jing , Huang Gao Gui , Zhang Yi Yu , Rui Li , Yao Shu Xiang . Correlation of 5-HT Transporter Protein Gene (SLC6A4) Polymorphism and Conduct Disorder in Children[J]. Journal of Kunming Medical University, 2017, 38(04): 28-31.

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Correlation of 5-HT Transporter Protein Gene (SLC6A4) Polymorphism and Conduct Disorder in Children

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基金：云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(2013FB113); 云南省教育厅科研基金资助项目(2016ZZX098,2016ZZX091);

Received Date: 2016-12-07

Abstract

Abstract

Objective To investigate the correlation of 5-HT transporter protein gene(SLC6A4)polymorphism and conduct disorder in children in primary and middle school in Kunming area. Methods Eighty-eight students with conduct disorder were studied. The technique of polytnerase Chain Reaction was used to study the SLC6A4 gene in conduct disorder. Results There was no statistically significant difference between conduct disorder and non-conduct disorder group in genotypes and allele frequencies. There was statistically significant difference in male group(P <0.05) but no in female group(P >0.05).Conclusions The SLC6A4 gene polymorphism may be correlated with conduct disorder in children.
- Conduct Disorder,
- Gene polymorphism,
- Transporter protein gene,
- 5-HT

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References(27)

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