CT Image Features of Castleman's Disease

Zhang Zong Quan; Zhao Xin Xiang; Liu Wen Jun; Liu Ke Ping; Liu Dai Liang; He Ming

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Article Navigation > Journal of Kunming Medical University > 2017 > 38(04): 58-62

Zhang Zong Quan , Zhao Xin Xiang , Liu Wen Jun , Liu Ke Ping , Liu Dai Liang , He Ming . CT Image Features of Castleman's Disease[J]. Journal of Kunming Medical University, 2017, 38(04): 58-62.

Citation:

Zhang Zong Quan , Zhao Xin Xiang , Liu Wen Jun , Liu Ke Ping , Liu Dai Liang , He Ming . CT Image Features of Castleman's Disease[J]. Journal of Kunming Medical University, 2017, 38(04): 58-62.

Zhang Zong Quan , Zhao Xin Xiang , Liu Wen Jun , Liu Ke Ping , Liu Dai Liang , He Ming . CT Image Features of Castleman's Disease[J]. Journal of Kunming Medical University, 2017, 38(04): 58-62.

Citation:

Zhang Zong Quan , Zhao Xin Xiang , Liu Wen Jun , Liu Ke Ping , Liu Dai Liang , He Ming . CT Image Features of Castleman's Disease[J]. Journal of Kunming Medical University, 2017, 38(04): 58-62.

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CT Image Features of Castleman's Disease

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基金：国家自然科学基金资助项目(81260213);

Received Date: 2016-09-05

Abstract

Abstract

Objective To explore the CT imaging features of Castleman's disease, and improve the awareness of Castleman's disease before surgery. Methods The clinical data and CT imaging data of 13 patients with pathologically proved Castleman's disease were analyzed retrospectively. Results Nine cases were localized with hyaline vascular type in pathological classification, including 4 cases in chest(2 cases in lung, 2 cases in mediastinum), 5 cases in abdomen(1 case in abdominal cavity and 4 case in retroperitoneum). Four cases were multicentric with lesions distributed in the lung, abdominal cavity, axillary and groin, and pathologically classified into hyaline vascular type in 1, plasma cell type in 10, and mixed type in 2.All lesions were of iso-density on plain CT with well-defined margin.After intravenous administration of contrast agent, the markedly and long-lasted enhancement was seen in all localized cases with hyaline vascular type. While multicentric cases showed different enhancement with correspond with different pathological classification, which 2 cases were markedly enhancement,but 2 cases were mild-moderate enhancemeny. Two of localized lesions were found with punctate, branching calcification, and 3 of localized lesions were found with peripheral scattered enlarged lymph nodes which were pathologically confirmed as reactive lymphadenitis. Conclusions The localized Castleman's disease with predominanthyaline vascular type has characteristics on CT images, including soft tissue mass with markedly and long-lasted enhancement, and some of cases with branching calcification and satellite lesions. However,multicentric Castleman's disease has no obvious features for diagnosis.
- Castleman's disease,
- Computed tomography,
- Features

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References(32)

References

[1]	[1]CASTLEMAN B,IVERSON L,MENENDEZ V P.Localized mediastinal lymphnode hyperplasia resembling thymoma.[J].Cancer,1 956,9(4):822-830.
[2]冉鹏程,单明,孙博,等.Castleman’S病的CT、MRI表现[J].中国临床医学影像杂志,2012,23(6):444-446.
[3] 栾云,黄海青,刘红霞,等.Castleman's病的CT表现[J].实用放射学杂志,2009,25(5):714-716.
[4]兰文杰,郝崴.巨淋巴结增生症的CT诊断[J].实用医学影像杂志,2013,14(5):368-369.
[5]	[5]TALAT N,SCHULTE K M.Castleman’s disease:systematic analysis of 416 patients from the literature[J].Oncologist,2011,16(9):1316-1324.
[6]贾明胜,姜玲,李盼盼,等.腹膜后局限性巨大淋巴结增生症的CT诊断[J].中国CT和MRI杂志,2012,10(5):71-74.
[7]	[7]MILLER E D,ROBB B W,CUMMINGS O W,et a1.The effects of preoperative chemoradiotherapy on lymphnode sampling in rectal cancer[J].Dis Colon Rectum,2O12,55(9):1002-1007.
[8]陈岚,强军,田燕晓,等.Castleman病的临床病理分析[J].世界最新医学信息文摘,2015,15(103):79-81.
[9]刘触灵,旷连勤.4例巨淋巴结增生症患者的影像学表现及文献复习[J].重庆医学,2014,43(11):1365-1368.
[10]那加,柳萍,王仁贵,等.Castleman病的临床病理观察[J].中华病理学杂志,2013,32(6):521-522.
[11]张晓斌,刘改萍,郑玄中,等.局限型Castleman病的CT表现与临床、病理分析[J].山西医科大学学报,2009,40(11):1022-1027.
[12]徐玉琴,张来顺,王春,等.胸腹部局灶型Castleman病的CT和MRI征像分析[J].医学影像学杂志,2015,25(10):1802-1806.
[13]刘艳玲,武淮昌,张东臣,等.腹部局灶型Castleman病的CT表现与病理分析[J].医学影像学杂志,2015,25(8):1394-1396.
[14]丁重阳,李天女.局限性Castleman病的CT影像学表现[J].中国临床医学影像杂志,2014,25(7):515-518.
[15]王仁贵,霍萌,王丹丹,等.胸腹部局限性Castleman病的CT特征分析[J].中华放射学杂志2010,44(11):1161-1166.
[16]李靖,赵绿洲,鲁乃浩,等.腹部巨淋巴结增生症的CT表现[J].实用放射学杂志,2014,30(10):1674-1675
[17]刘晓红,印建国,宋锦文,等.Castleman病的影像学表现与手术、病理对照分析[J].临床军医杂志,2011,39(5):909-912.
[18]李佩玲,常妙,刘婷,等.巨淋巴结增生症的多层螺旋CT表现[J].中华放射学杂志,2013,47(1):64-67.
[19]	[19]MIKROULIS D,TSAKIRIDIS K,KALOUTSI V,et al.Mediastinal Castleman disease with calcific deposits.Eur J Cardiothorac Surg,2004,25(1):135-136.
[20] 李伟雄,韩秋丽,卢炳丰,等.Castleman病的MSCT表现[J].实用放射学杂志,2011,27(11):1725-1727.
[21]潘鑫,毕纯龙,万霞,等.腹部Castleman's病的多层螺旋CT表现[J].中国临床医学影像杂志,2008,19(4):239-242.
[22]王洪斌,刘付广.巨淋巴结增生症的CT征像分析[J].中国实用医药,2011,6(36):180-181.
[23]李麦福,丁同文.局限型巨淋巴结增生症的MSCT表现与病理对照分析[J].中国中西医结合影像学杂志,2013,11(5):518-519.
[24]刘金全,文海忠,朱志嫦,等.巨淋巴结增生症的CT诊断价值[J].中国医药指南,2015,13(20):226-227.
[25]张淼,刘愉,蒋伟,等.胸内巨淋巴结增生症外科诊治12例临床分析[J].徐州医学院学报,2012,32(10):683-685.
[26]邓丹,李春平,杨帆,等.纵隔滑膜肉瘤2例报告并文献复习[J].川北医学院学报,2014,29(2):170-172.
[27]李克勤,杨仁荣.腹膜后巨大副神经节瘤2例报告并文献复习[J].川北医学院学报,2015,30(4):516-519.
[28]杨小芸,龙庭凤,沈丽达,等.霍奇金淋巴瘤143例的临床诊疗[J].昆明医科大学学报,2016,37(6):117-122.
[29]虞涛,曲丽峰,李英华,等.肺部实质性占位病变110例影像学及病理学诊断的准确性[J].昆明医科大学学报,2016,37(4):128-131.
[30]李宝新.Castleman病的CT诊断价值[J].山西医药杂志,2011,40(12):1205-1206.
[31]党勇,尚淑平.64排CT联合血清学检查对非小细胞性肺癌纵隔淋巴结转移的诊断[J].昆明医科大学学报,2014,35(3):125-128.
[32]周华亭,左瑞,柳梅玲,等.巨淋巴结增生症的CT表现[J].中国中西医结合影像学杂志,2015,13(1):104-105.

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