Treatment Efficacy of Pantoprazole and Domperidone on Larygopharyngeal Reflux Disease

Ma Yan; Niu Yan; Wu Hai Ying; Lv Cao; Bai Zhong

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Article Navigation > Journal of Kunming Medical University > 2017 > 38(04): 98-100

Ma Yan , Niu Yan , Wu Hai Ying , Lv Cao , Bai Zhong . Treatment Efficacy of Pantoprazole and Domperidone on Larygopharyngeal Reflux Disease[J]. Journal of Kunming Medical University, 2017, 38(04): 98-100.

Citation:

Ma Yan , Niu Yan , Wu Hai Ying , Lv Cao , Bai Zhong . Treatment Efficacy of Pantoprazole and Domperidone on Larygopharyngeal Reflux Disease[J]. Journal of Kunming Medical University, 2017, 38(04): 98-100.

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Treatment Efficacy of Pantoprazole and Domperidone on Larygopharyngeal Reflux Disease

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基金：云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(NC003-3-R02);

Received Date: 2016-12-21

Abstract

Abstract

Objective To explore the clinical effects of Pantoprazole and Domperidone on larygopharyngeal reflux disease. Methods Eighty patients with initial diagnosis of laryngopharyngeal reflux disease(LPRD) were divided into observation group(40 cases) and control group(40 cases) according to different treatment methods.In the observation group,patients were given pantoprazole 10 mg/times,3 times/day,at 30 minutes before meals,for 8 weeks. The patients in the control group were treated with conventional pharyngeal and pharyngeal laryngeal drugs. The clinical symptoms and signs of the two groups were recorded and compared. Results In the observation group,the significantly effective was in 20 cases,effective in 11 cases, ineffective in 9 cases, the total effective rate was 77.5%;in the control group, the significantly effective was in 3 cases,effective in 5 cases,32 cases were ineffective,the total effective rate was 20%. There was significant difference in total effective rate between the two groups(P<0.05). Conclusion Pantoprazole combined with domperidone is an effective method for the treatment of larypharyngeal reflux disease.
- Pantoprazole,
- Domperidone,
- Larygopharyngeal reflux disease,
- Treatment

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References(16)

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