Comparison of Caspase-9 Expression in Condylar Cartilage and Growth Plate Cartilage in the Development Process

He Ying; Mao Rui; Liu Shao Mei; Li Yi Ying; Li Song

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He Ying , Mao Rui , Liu Shao Mei , Li Yi Ying , Li Song . Comparison of Caspase-9 Expression in Condylar Cartilage and Growth Plate Cartilage in the Development Process[J]. Journal of Kunming Medical University, 2017, 38(07): 16-21.

Citation:

He Ying , Mao Rui , Liu Shao Mei , Li Yi Ying , Li Song . Comparison of Caspase-9 Expression in Condylar Cartilage and Growth Plate Cartilage in the Development Process[J]. Journal of Kunming Medical University, 2017, 38(07): 16-21.

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Comparison of Caspase-9 Expression in Condylar Cartilage and Growth Plate Cartilage in the Development Process

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基金：国家自然科学基金资助项目 (81360163);

Received Date: 2017-04-20

Abstract

Abstract

Objective To investigate the different expression of Caspase-9 in condylar cartilage and growth plate cartilage and to explore the role of Caspase-9 in the development of cartilage.Methods Animal models of condylar cartilage and growth plate cartilage of SD rat were established during different development stages (E15d-P30d) . The expressions of Caspase-9 were examined by immuno-histochemical staining. Results Positive xpression of Caspase-9 expression in condylar cartilage was stronger than that in growth plate cartilage (P<0.05) .The distribution of positive cells in growth plate cartilage is consistent with those in the condylar cartilage. Caspase-9 positive of fetal rat mainly expressed in the proliferative zone and expressed in the chondroblast zone and hypertrophic zone after birth. Conclusion Caspase-9 is involved in the growth and development of condylar cartilage and growth plate cartilage, which may play an important role in the development of cartilage. Caspase-9 may be of the same or similar molecular mechanism for the development of condylar cartilage and growth plate cartilage.
- Condylar cartilage,
- Growth plate cartilage,
- Development,
- Caspase-9

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References(15)

References

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