Volume 38 Issue 07
. 
Turn off MathJax
Article Contents
Abstract
References
Relative Articles
Article Navigation >  Journal of Kunming Medical University  > 2017  >  38(07): 73-75
Li Jin Tao , Ma Yi , Zhang Yu Wen , Tang Ying , Wang Qiong Xian , Zheng Hong . Effects of Alcohol on Hematological Indexes of Tupaia Belangeri Chinensis[J]. Journal of Kunming Medical University, 2017, 38(07): 33-36.
Citation: Li Lan Jiang , Xu Bing Ying , Yang Chun Yan , Zhao Chuan , Tian Xin . Correlative Studies between MMP1 Gene Polymorphism and the Risk of Oral Squamous Cell Carcinomas among Han Nationality in Yunnan Province[J]. Journal of Kunming Medical University, 2017, 38(07): 73-75.
shu

Correlative Studies between MMP1 Gene Polymorphism and the Risk of Oral Squamous Cell Carcinomas among Han Nationality in Yunnan Province

Funds:

基金： 云南省应用基础研究计划项目 (2011FZ103);

  • Received Date: 2017-03-21
    Abstract
  • Objective To explore the correlation between MMP1 gene polymorphisms and risk of oral squamous cell carcinomas among Han nationality in Yunnan province and to provide experimental reference for discovery and screening of susceptibility genes of oral squamous carcinoma.Methods Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was applied to detect individual MMP1 promoter-1607 1G/2G loci single nucleotide polymorphisms (SNP) in patients with oral squamous cell carcinomas and control group. The genotype of the patients with oral squamous carcinoma was obtained and compared with that in the control group. Results The genotype frequencies of MMP1 promoter-1607 1G/2G, 1G/1G, 2G/2G, 1G/2G were 11.11% and37.04%, 51.85% and 5.66%, 43.40% and 50.94% in control group and case group respectively. There was no significant difference between MMP1 SNP and the risk of oral squamous cell carcinomas (P>0.05) . No significant difference was found when MMP1 SNP was compared with high, medium and low differentiation of oral squamous cell carcinomas (P>0.05) . Conclusion There is no correlation between MMP1 promoter-1607 1G/2G loci SNP and the risk of oral squamous carcinoma among Han nationality in Yunnan province.
    • FullText(HTML)
    • References(6)
  • [1]
    [1]BAKER E A, LEAPER D J, HAYTER J P, et al.The matrix metalloproteinase syestem in oral squamous cell carcinoma[J].Br J Oral Maxillofac Surg, 2006, 44 (6) :482-486.
    [2]
    [2]LI X, QU L, ZHANG Y, et al.Association between promoters polymorphisms of matrix metalloproteinases and risk of digestive cancers:a meta-analysis[J].Journal of cancer research and clinical oncology.-September 1, 2013, 139 (9) :1433-1447.
    [3]陈丽, 向丽, 周铁军, 等.口腔鳞癌中RECK和MMP-9蛋白的表达及临床意义[J].泸州医学院学报, 2014, 37 (1) :75-78.
    [4]
    [4]ZHANG C, SONG X, ZHU M, et al.Association between MMP1-1607 1G>2G polymorphism and head and neck cancer risk:a meta-analysis[J].PLo S One, 2013, 8 (2) :e56294.
    [5]
    [5]MATSUMURA S, OUE N, KITADAI Y, et al.A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer[J].J Cancer Res Clin Oncol, 2004, 130 (5) :259-265.
    [6]戴巧群, 单海琴, 任雨, 等.基质金属蛋白酶一1基因启动子区 (-1 607) 基因多态性与肾移植后环孢素诱导牙龈增生的相关性[J].中国现代医生, 2014, 52 (30) :152-155.
    • Relative Articles(20)

  • Relative Articles

    [1] Boyi LI, Ling NIU, Rong MA, Xian ZHANG, Fang LIU, Yan TANG, Cuijuan MIAO, Cheng ZHANG, Zhujun HAN. The Relationship Between T950C Polymorphism in the Promoter Region of Osteoprotegerin Gene and Type 2 Diabetes with Osteoporosis. Journal of Kunming Medical University, 2022, 43(3): 67-73.  doi: 10.12259/j.issn.2095-610X.S20220306
    [2] Yunxin ZHAO, Fanyuan MENG, Wei LIU, Huidong WU, Changliang LUO, Bin LI, Lijuan AO, Moxian CHEN. Research Progress of Single Nucleotide Polymorphism and Adolescent Idiopathic Scoliosis. Journal of Kunming Medical University, 2022, 43(11): 156-164.  doi: 10.12259/j.issn.2095-610X.S20221121
    [3] Li Jia Li , Zhou Xiao Wei , Guo Wei Chang , Chen Jie , Zhang Fan , Li Hui Fang . . Journal of Kunming Medical University, 2020, 41(06): 60-66.
    [4] Zhang Xu Xiang , Li Wen , Wang Fang , Lin Meng Jie , Li Hong , Zhang Li , Nian Xin . . Journal of Kunming Medical University, 2020, 41(05): 18-22.
    [5] Nie Ai Ting , Ji Ai Cen , Hu Li Ping , Zhang Xiu Feng , Liu Lin Lin , Li Jia Jue , Nie Sheng Jie . . Journal of Kunming Medical University, 2019, 40(10): 175-180.
    [6] Jiang Hong Yan , Ran Liu Yi , Wu Gui Xia , Xu Xiu Feng , Yu Li . A Study of Correlation between NDST3 Gene Polymorphism and Schizophrenia Among Han People in Yunnan. Journal of Kunming Medical University, 2018, 39(02): 51-54.
    [7] Yao Jin Yong , Hu Li Ping , Nie Ai Ting , Huang Ren Wu , Qiu Jian Bo , Zhang Xiu Feng , Rao 旼, Nie Sheng Jie . Establishment and Application An Automatic Typing Method for MAOA μ-VNTR Polymorphism Test using Fluorescence Labeling Techniques. Journal of Kunming Medical University, 2017, 38(06): 52-55.
    [8] Zhang Jin Yu , Peng Zhuo Hui . Relationship between Single Nucleotide Polymorphisms of ERCC Gene and Survival of Osteosarcoma. Journal of Kunming Medical University, 2017, 38(09): 59-65.
    [9] Nian Xin . Difference of Metallothionein Gene G-201A Polymorphism in Type 2 Diabetes and Essential Hypertension. Journal of Kunming Medical University,
    [10] Lan Dan Feng . . Journal of Kunming Medical University,
    [11] Li Ying Fu . . Journal of Kunming Medical University,
    [12] An Xin Huan . . Journal of Kunming Medical University,
    [13] Li Hui Fang . . Journal of Kunming Medical University,
    [14] Yan Zhi Ling . . Journal of Kunming Medical University,
    [15] Li Ying Fu . . Journal of Kunming Medical University,
    [16] Deng De Yao . . Journal of Kunming Medical University,
    [17] Chen Can . . Journal of Kunming Medical University,
    [18] Nian Xin . The Preliminary Analysis of the FOXC2 C-1702T Polymorphism is Associated with Cholesterol. Journal of Kunming Medical University, 2012, 33(02): 1-1.
    [19] He Bao Li . . Journal of Kunming Medical University,
    [20] Li Hui Fang . . Journal of Kunming Medical University,
    • Supplements(0)
    • Cited By

  • Cited by

    Periodical cited type(4)

    1. 邵光辉. 云南白药胶囊辅助经皮微创内固定术对胫骨平台骨折患者愈合的影响. 中华养生保健. 2024(07): 23-26 .
    2. 华长城，杨飞，孙治强，王小合. 加长股骨近端防旋髓内钉治疗SeinsheimerⅤ型股骨转子下骨折的疗效. 局解手术学杂志. 2024(06): 532-534 .
    3. 任文清，王伟，平伟，庞超. 股骨粗隆间骨折患者接受生物加长柄关节置换治疗的疗效分析. 现代医学与健康研究电子杂志. 2024(10): 60-64 .
    4. 陈涛，董盼锋，章晓云，梁庆华，龙飞攀，陈跃平. 非骨水泥股骨假体置换联合术中股骨大转子重建对不稳定股骨转子间骨折的疗效分析. 中国现代医学杂志. 2022(18): 70-76 .

    Other cited types(0)

  • Created with Highcharts 5.0.7Amount of accessChart context menuAbstract Views, HTML Views, PDF Downloads StatisticsAbstract ViewsHTML ViewsPDF Downloads2024-052024-062024-072024-082024-092024-102024-112024-122025-012025-022025-032025-0400.250.50.7511.25
    Created with Highcharts 5.0.7Chart context menuAccess Class DistributionFULLTEXT: 27.4 %FULLTEXT: 27.4 %META: 72.3 %META: 72.3 %PDF: 0.3 %PDF: 0.3 %FULLTEXTMETAPDF
    Created with Highcharts 5.0.7Chart context menuAccess Area Distribution其他: 4.2 %其他: 4.2 %China: 4.4 %China: 4.4 %上海: 6.7 %上海: 6.7 %东莞: 0.1 %东莞: 0.1 %九江: 0.1 %九江: 0.1 %北京: 32.0 %北京: 32.0 %安那罕: 0.0 %安那罕: 0.0 %宣城: 0.0 %宣城: 0.0 %张家口: 0.0 %张家口: 0.0 %日照: 0.1 %日照: 0.1 %昆明: 0.1 %昆明: 0.1 %杭州: 0.0 %杭州: 0.0 %武汉: 0.0 %武汉: 0.0 %深圳: 0.1 %深圳: 0.1 %温州: 0.0 %温州: 0.0 %湖州: 0.0 %湖州: 0.0 %漯河: 0.0 %漯河: 0.0 %濮阳: 0.0 %濮阳: 0.0 %盐城: 0.1 %盐城: 0.1 %芒廷维尤: 1.2 %芒廷维尤: 1.2 %衢州: 0.0 %衢州: 0.0 %西宁: 2.6 %西宁: 2.6 %贵阳: 0.0 %贵阳: 0.0 %运城: 0.0 %运城: 0.0 %郑州: 0.5 %郑州: 0.5 %重庆: 0.0 %重庆: 0.0 %长沙: 0.0 %长沙: 0.0 %驻马店: 47.4 %驻马店: 47.4 %其他China上海东莞九江北京安那罕宣城张家口日照昆明杭州武汉深圳温州湖州漯河濮阳盐城芒廷维尤衢州西宁贵阳运城郑州重庆长沙驻马店

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF
    XML

    Article Metrics

    Article views (2591) PDF downloads(36) Cited by(4)
    Proportional views
    Related

    Copyright © 《昆明医科大学学报》编辑部  滇ICP备00000000号-0

    Publishing: 昆明医科大学学报编辑部

    Supported by: Beijing Renhe Information Technology Co. Ltd    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return