Yang Bi Qing , Wang Xun . Significance of Serum Total Bilirubin Level in Cerebral Emergencies[J]. Journal of Kunming Medical University, 2017, 38(09): 66-70.
Citation: Yang Bi Qing , Wang Xun . Significance of Serum Total Bilirubin Level in Cerebral Emergencies[J]. Journal of Kunming Medical University, 2017, 38(09): 66-70.

Significance of Serum Total Bilirubin Level in Cerebral Emergencies

Funds:

基金: 云南省教育厅科学研究基金资助项目 (2016ZDX072);

  • Received Date: 2017-04-21
  • Objective To observate and analyze the significance of serum total bilirubin level detected in cerebral emergencies.Methods A total of 62 patients with cerebral infarction (incidence ≤2 weeks) in the People's Hospital of Dehong from September 2013 to July 2015 were selected as the observation group, another 62 cases of examination of patients were selected as a control group.Then we compared the biochemical indexes including serum total bilirubin, blood lipids and blood sugar within 72 h after admission between two groups of patients.Results For patients in the observation group, serum levels o f triglyceride, total cholesterol, high density lipoprotein cholesterol, diastolic blood pressure, systolic blood pressure, fasting blood glucose were significantly higher than the control group [ (1.85±0.36) mmol/L vs (1.36 ±0.21) mmol/L, (4.9 ±1.5) mmol/L vs (4.5±1.1) mmol/L, (1.56±0.39) mmol/L vs (1.43±0.28) mmol/L, (83.1±11.5) mm Hg vs (75.2±10.3) mm Hg, (132.5±22.4) mm Hg vs (117.3±19.8) mm Hg, (5.9±0.3) mmol/L vs (5.3±0.9) mmol/L, Low density lipoprotein cholesterol was lower than the control group [ (2.01±0.29) mmol/L vs (2.41 ±0.37) mmol/L].Serum total bilirubin, direct bilirubin, indirect bilirubin of observation group was significantly higher than the control group [ (15.1±3.8) μmol/L vs (12.1±3.5) μmol/L, (4.6±1.1) μmol/L vs (3.9±1.3) μmol/L, (10.5±2.1) μmol/L vs (8.1±1.4) μmol/L], the difference was statistically significant (P<0.05) .Varying degrees of neurological impairment with total bilirubin, directbilirubin, indirect bilirubin had no significant difference (P>0.05) .Good prognosis group total bilirubin, directbilirubin, indirect bilirubin levels were significantly higher than the poor prognosis group [ (16.1±3.7) μmol/L vs (11.9±2.9) μmol/L, (4.9±1.1) μmol/L vs (3.6±1.1) μmol/L, (11.2±2.1) μmol/L vs (8.2±2.3) μmol/L], the difference was statistically significant (P<0.05) .Conclusion Serum levels of total bilirubin in patients is beneficial for the early diagnosis and treatment of patients with cerebral infarction, and determine the prognosis.
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