Yiling ZUO, Jiayan SUN, Limei MING, Guilan ZHANG, Yunxia SHEN, Xiaolin ZHANG. The Health Education Based on Cognitive Behavioral Therapy in Patients with Colorectal Cancer during the Chemotherapy Intervals and Its Application in the Virtual Community Nursing[J]. Journal of Kunming Medical University, 2024, 45(11): 174-180. doi: 10.12259/j.issn.2095-610X.S20241125
Citation: Pan Bao Long , Wu Ling , Pan Li , Zhang Yuan Yuan , Li Jun E , Zhan Xue Liang . Application of Related Laboratory Indexes in Early Rheumatoid Arthritis[J]. Journal of Kunming Medical University, 2017, 38(11): 96-100.

Application of Related Laboratory Indexes in Early Rheumatoid Arthritis

Funds:

基金: 云南省高层次卫生技术人才专项基金资助项目 (D-201206);

  • Received Date: 2017-06-17
  • Objective To evaluate the current related laboratory indicators of rheumatoid arthritis (RA) and screening out the optimal early RA-related indicators.Methods We selected 158 cases as RA group, 121 cases as early RA group, 100 cases as normal control group.The total rheumatoid factor and other 14 indicators were measured and analyzed statistically in each group.No statistical differences indicators were observed, the ROC curve was used to evaluate the diagnostic efficacy of the remaining indicators in early RA, AUC>0.75 as the standard, indicators with diagnostic efficacy were initially screened.The sieve out indicators were used for bivariate correlation analysis, significant correlates are classified as a same class.Results (1) Among the 14 indicators, except for RF IgA and CRP, the other indexes were significantly different in the three groups (P<0.05) .There were 6 indexes which exceeding 0.75 of area under the single index curve (AUC) :GPI (0.929) , anti-MCV (0.923) , RF IgG (0.904) , anti-CCP (0.901) , APF (0.891) and total RF (0.880) ; (3) By bivariate correlation analysis, there was a significant positive correlation between the six indexes and whether they were early RA, and classified as 3 groups:GPI group, anti-MCV group (including anti-CCP and APF) , RF IgG group (including total RF) .Conclusion In the 14 indicators, only 6 indicators (GPI class, anti-MCV class and RF IgG class) have higher diagnostic efficacy for early RA, we only need to choose one to carry out in each category in practice, so as to avoid clinical and laboratory duplication or low-performance testing.
  • [1]
    [1]KARLSON E W, SCHAARDENBURG D, HELM-VAN MIL A H, et al.Strategies to predict rheumatoid arthritis development in at-risk populations[J].Rheumatology (Oxford) , 2016, 55 (1) :6-15.
    [2]
    [2]ALETAHA D, NEOGI T, SILMAN A T, et al.Rheumatoid arthritis classification criteris:an American Collefe of Rheumatology/European League Against Rheumatism collaborative initative[J].Arthritis Rheum, 2010, 62 (9) :2569-2581.
    [3]
    [3]KANEKO Y, KUWANA M, KAMEDA H, et al.sensitivity and specificity of 2010 rheumatoid arthritis classification criteria[J].Rheumatology (Oxford) , 2011, 50 (7) :1268-1274.
    [4]
    [4]KATZ P, MARGARETTEN M, TRUPIN L, et al.Role of sleep disturbance, depression, obesity, and physical inactivity in fatigue in rheumatoid arthritis[J].Arthritis Care Res (Hoboken) , 2016, 68 (1) :81-90.
    [5]
    [5]ARNETT F C, EDWORTHY S, BLOCK D A, et al.The1987 revised ARA criteria for rheumatoid arthritis[J].Arthritis Rheum, 1987, 30 (1) :17-21.
    [6]于峰.C反应蛋白与血沉在类风湿性关节炎中的应用价值[J].中国现代药物应用, 2017, 11 (1) :67-68.
    [7]盖楠楠, 李国晖.类风湿性关节炎患者血清RF、抗CCP抗体联合检测的临床意义[J].昆明医科大学学报, 2017, 38 (3) :111-114.
    [8]
    [8]AJEGANOVA S, VAN STEENBERGEN H W, VERHEUL M K, et al.The association between anti-carbamylated protein (anti-Car P) antibodies and radiographic progression in early rheumatoid arthritis:a study exploring replication and the added value to ACPA and rheumatoid factor[J].Ann Rheum Dis, 2017, 76 (1) :112-118.
    [9]
    [9]SCHELLEKENS, ZHOU W, ZHANG Z L, et al.A comparative study on the diversity of clinical features between the sero-negative and sero-positive rheumatoid arthritis patients[J].Rheumatol Int, 2000, 18 (12) :3897-3901.
    [10]
    [10]CRISTINA I, ANNA M, LEONOR N, et al.The antigen specificity of the rheumatoid arthritis associated ACPA directed to citrullinated fibrin is very closely restricted[J].Autoimmunity, 2015, 37 (4) :263-272.
    [11]梁鹏, 安宏亮, 张劲丰.抗环瓜氨酸肽抗体对类风湿关节炎的诊断及与骨侵蚀相关研究[J].中国卫生检验杂志, 2015, 25 (1) :62-64.
    [12]覃仕锋, 李春美.自身抗体检测在自身免疫性疾病中的价值[J].中国免疫学杂志, 2015, 31 (3) :401-403.
    [13]
    [13]ROY N, TANNER K, MERRILL R M, et al.Descriptive epidemiology of voice disorders in rheumatoid arthritis:prevalence, risk factors, and quality of life burden[J].J Voice, 2016, 30 (1) :74-87.
    [14]
    [14]LU Q, CUI Y, YE C, et al.Bagging optimal roc curve method for predictive genetic tests, with an application for rheumatoid arthritis[J].J Biopharm Stat, 2010, 20 (2) :401-414.
    [15]
    [15]HUFFMAN K M, JESSEE R, ANDONIAN B, et al.Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability[J].Arthritis Res Ther, 2017, 19 (1) :12-17.
  • Relative Articles

    [1] Yanbi ZHANG, Lei FENG, Rui SHI, Beibei LUO, Lingtong TANG, Huiying CAO, Qianye BI. Diagnostic Efficacy of Blood Inicators in the Diagnosis and Treatment of Gram-positive Cocci and Gram-negative Bacilli Infection. Journal of Kunming Medical University, 2023, 44(12): 111-120.  doi: 10.12259/j.issn.2095-610X.S20231218
    [2] Jianfei LU, Rui BU, Xiaoyan LIU, Xing ZHANG, Yu DING, Ran ZHANG. Efficacy of Conventional Ultrasound and Contrast-enhanced Ultrasound in Preoperative Diagnosis of Lateral Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma. Journal of Kunming Medical University, 2022, 43(12): 75-80.  doi: 10.12259/j.issn.2095-610X.S20221214
    [3] Xia LI, Jin WANG. Comparions of the Diagnostic Value between Digital Breast Tomosynthesis and Full-field Digital Mammography. Journal of Kunming Medical University, 2022, 43(9): 118-124.  doi: 10.12259/j.issn.2095-610X.S20220914
    [4] Congxin LI, Dapeng ZHANG, Lingjie MU, Jilin YANG, Lihong DONG, Yijie WANG. The Value of HCT-ALB in the Early Diagnosis of Sepsis-associated Encephalopathy. Journal of Kunming Medical University, 2022, 43(9): 24-28.  doi: 10.12259/j.issn.2095-610X.S20220901
    [5] Qin XIE, Yan-ping LIANG, Yin ZHANG, Zeng-hui XU, Li-ying YOU. Efficacy of Multiple Non-invasive Diagnostic Models in the Diagnosis of Hepatic Fibrosis in Patients with Chronic Liver Diseases. Journal of Kunming Medical University, 2021, 42(7): 115-120.  doi: 10.12259/j.issn.2095-610X.S20210719
    [6] Yan LIANG, Jian-bo GAO, Jun-yan MA, Hao YANG. Diagnostic Effect and Imaging Characteristics of High Frequency Ultrasound in Limb Skeletal Muscle Injury. Journal of Kunming Medical University, 2021, 42(10): 157-161.  doi: 10.12259/j.issn.2095-610X.S20211015
    [7] Shu-lan SHI, Xi-ting DAI, Guang-zhou ZHAO, Xiao Juan LI, Rong-jie LI, Ming-biao MA. Application of 16SrRNA Gene Detection in the Early Diagnosis of Bacterial Meningitis in Children. Journal of Kunming Medical University, 2021, 42(5): 120-125.  doi: 10.12259/j.issn.2095-610X.S20210522
    [8] Xue LOU, Li LIAO, Ruo-tong ZHAO, Xiang-yu WANG, Yi-fan YANG, Shuang LIU, Jian XU. Clinical Significance of Anti-dsDNA Antibody,Complement C3 and Other Laboratory Indicators in the Diagnosis of Renal Injury in Systemic Lupus Erythematosus. Journal of Kunming Medical University, 2021, 42(2): 49-53.  doi: 10.12259/j.issn.2095-610X.S20210214
    [9] Ting-ting YU, Xiao-fei LI, Hong-ying WANG, Run-wu ZHANG, Cai-mei DING, Li-hua LI, Jing BAI, Dong-ling LI, Dong PU. Application of Viral Load Testing in Diagnosing 102 Cases of Indeterminate HIV Antibody. Journal of Kunming Medical University, 2020, 41(11): 130-133.  doi: 10.12259/j.issn.2095-610X.S20201126
    [10] Ying ZHANG, Xiao-qun NIU. The Diagnostic Efficacy of Alveolar Lavage Fluid G test and GM Test in AECOPD Complicated with Invasive Pulmonary Fungal Infection. Journal of Kunming Medical University, 2020, 41(12): 55-59.  doi: 10.12259/j.issn.2095-610X.S20201217
    [11] Wu Qi Yan , Bian Ge Yuan , Cheng Hui Jun, Li Jiao Xia , Wang Shu Ting , Huang Zhao Lue . . Journal of Kunming Medical University, 2020, 41(09): 32-37.
    [12] Lin-kun TA, Yan-ling HUANG, Yong-ping LU. Application of Ultrasonographic Scoring Combined with Enhanced Blood Flow Display Technique in Dangerous Placenta Previa with Placental Implantation. Journal of Kunming Medical University, 2020, 41(11): 119-123.  doi: 10.12259/j.issn.2095-610X.S20201112
    [13] Liu Ming Min , Wang Li Chun , Liang Xi , Yang Rui . Application of Ultrasound-guided Breast Microscopic Lesion Biopsy in the Early Diagnosis of Breast Cancer. Journal of Kunming Medical University, 2018, 39(07): 37-40.
    [14] Mei Rong , Chen Wen Li , Zhang Feng Li , Meng Qiang , Zhao Zhong , Ding Li . . Journal of Kunming Medical University, 2017, 38(03): 64-70.
    [15] Wu Xiao Tao , Li Chuan Jun , Wu Xin , Zhong Shi Yan . . Journal of Kunming Medical University, 2017, 38(03): 98-102.
    [16] Ma Fang Wei , Liu Min , Sun Yan Ling , Zhao Hao Yu , Yin Qing , He Hui Zhong . . Journal of Kunming Medical University, 2017, 38(05): 120-124.
    [17] Pan Li , Pan Bao Long , Li Jun E , Wu Ying Song . Laboratory Diagnosis and Correlation Analysis on Rheumatoid Arthritis Complicated with Coronary Heart Disease. Journal of Kunming Medical University, 2017, 38(06): 82-86.
    [18] Gai Nan Nan , Li Guo Hui . . Journal of Kunming Medical University, 2017, 38(03): 111-114.
    [19] Xu Rong . The Value of Detecting Paratracheal Lymph Nodes by Ultrasonography in Diagnosis of Autoimmune Thyroiditis. Journal of Kunming Medical University,
    [20] Yang Yu Zhou . . Journal of Kunming Medical University,
  • Created with Highcharts 5.0.7Amount of accessChart context menuAbstract Views, HTML Views, PDF Downloads StatisticsAbstract ViewsHTML ViewsPDF Downloads2024-052024-062024-072024-082024-092024-102024-112024-122025-012025-022025-032025-04050100150200
    Created with Highcharts 5.0.7Chart context menuAccess Class DistributionFULLTEXT: 26.4 %FULLTEXT: 26.4 %META: 73.2 %META: 73.2 %PDF: 0.4 %PDF: 0.4 %FULLTEXTMETAPDF
    Created with Highcharts 5.0.7Chart context menuAccess Area Distribution其他: 7.0 %其他: 7.0 %其他: 0.4 %其他: 0.4 %China: 0.1 %China: 0.1 %Grove City: 0.1 %Grove City: 0.1 %San Mateo: 0.1 %San Mateo: 0.1 %三明: 0.2 %三明: 0.2 %上海: 1.2 %上海: 1.2 %东京: 0.1 %东京: 0.1 %九江: 0.1 %九江: 0.1 %伊利诺伊州: 0.1 %伊利诺伊州: 0.1 %六安: 0.4 %六安: 0.4 %兰州: 0.1 %兰州: 0.1 %北京: 49.0 %北京: 49.0 %十堰: 0.5 %十堰: 0.5 %南宁: 0.3 %南宁: 0.3 %呼和浩特: 0.1 %呼和浩特: 0.1 %哈尔滨: 0.1 %哈尔滨: 0.1 %哥伦布: 0.3 %哥伦布: 0.3 %嘉兴: 0.4 %嘉兴: 0.4 %天津: 0.8 %天津: 0.8 %宣城: 0.2 %宣城: 0.2 %宿州: 0.1 %宿州: 0.1 %常州: 0.4 %常州: 0.4 %常德: 0.1 %常德: 0.1 %广州: 0.1 %广州: 0.1 %延安: 0.1 %延安: 0.1 %张家口: 4.1 %张家口: 4.1 %徐州: 0.1 %徐州: 0.1 %意法半: 0.2 %意法半: 0.2 %成都: 0.3 %成都: 0.3 %扬州: 0.8 %扬州: 0.8 %昆明: 2.1 %昆明: 2.1 %朝阳: 0.1 %朝阳: 0.1 %杭州: 0.4 %杭州: 0.4 %楚雄: 0.1 %楚雄: 0.1 %武汉: 0.1 %武汉: 0.1 %济南: 0.1 %济南: 0.1 %淄博: 0.1 %淄博: 0.1 %深圳: 0.2 %深圳: 0.2 %温州: 0.9 %温州: 0.9 %湖州: 0.2 %湖州: 0.2 %漯河: 2.8 %漯河: 2.8 %石家庄: 0.2 %石家庄: 0.2 %福州: 0.2 %福州: 0.2 %纽约: 0.3 %纽约: 0.3 %芒廷维尤: 14.2 %芒廷维尤: 14.2 %芝加哥: 0.3 %芝加哥: 0.3 %衡阳: 0.1 %衡阳: 0.1 %西宁: 6.8 %西宁: 6.8 %贵阳: 0.1 %贵阳: 0.1 %赣州: 0.1 %赣州: 0.1 %运城: 0.2 %运城: 0.2 %遵义: 0.1 %遵义: 0.1 %邯郸: 0.5 %邯郸: 0.5 %郑州: 0.8 %郑州: 0.8 %长春: 0.1 %长春: 0.1 %长沙: 0.4 %长沙: 0.4 %随州: 0.1 %随州: 0.1 %马鞍山: 0.1 %马鞍山: 0.1 %其他其他ChinaGrove CitySan Mateo三明上海东京九江伊利诺伊州六安兰州北京十堰南宁呼和浩特哈尔滨哥伦布嘉兴天津宣城宿州常州常德广州延安张家口徐州意法半成都扬州昆明朝阳杭州楚雄武汉济南淄博深圳温州湖州漯河石家庄福州纽约芒廷维尤芝加哥衡阳西宁贵阳赣州运城遵义邯郸郑州长春长沙随州马鞍山

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (4011) PDF downloads(81) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return