The Effect of Early Nasal Jejunum Nutrition on the Inflammatory Markers of Severe Acute Pancreatitis

Pan Rui; Shi Hong; Yang Xiao Juan

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Pan Rui , Shi Hong , Yang Xiao Juan . The Effect of Early Nasal Jejunum Nutrition on the Inflammatory Markers of Severe Acute Pancreatitis[J]. Journal of Kunming Medical University, 2018, 39(01): 100-103.

Citation:

Pan Rui , Shi Hong , Yang Xiao Juan . The Effect of Early Nasal Jejunum Nutrition on the Inflammatory Markers of Severe Acute Pancreatitis[J]. Journal of Kunming Medical University, 2018, 39(01): 100-103.

Citation:

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The Effect of Early Nasal Jejunum Nutrition on the Inflammatory Markers of Severe Acute Pancreatitis

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基金：玉溪市人民医院院内基金资助项目 (YXSRMYY-2016-20);

Received Date: 2017-10-17

Abstract

Abstract

Objective The present study aims to investigate the effect of the early nasal jejunum nutrition (NJN) on the inflammatory markers of severe acute pancreatitis (SAP) and to research if the NJN improves the recovery of SAP. Method SAP inpatients were observed during 2016. One group who accepted the NJN was experimental group and another group who did not accept the NJN was control group.The difference of serum albumin (ALB) , procalcitonin (PCT) , C reactive was compared to observe the effect of the early nasal jejunum nutrition (NJN) on the inflammatory markers of severe Acute Pancreatitis protein (CRP) , interleukin 6 (IL-6) and serum amylase (AMY) between the highest and lowest levels in two group respectively and the time of diet recovery between two groups. Results (1) The difference of interleukin 6 (IL-6) between the highest and lowest levels in experimental group was significantly smaller than that of the control group;the difference of ALB, CRP and PCT between the highest and lowest levels in experimental group was not different from the control group;2) The time of diet recovery of experimental group was shorter than that of the control group. Conclusion The early NJN can reduce the IL-6 level and the time of diet recovery, and then, improve the SAP recovery.
- Severe acute pancreatitis,
- Nasal jejunum nutrition,
- Inflammatory marks

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References(19)

References

[1]	[1]BAKKER O J, SANTVOORT H C et al.Pancreatitis, very early compared with normal start of enteral feeding:design and rational of a randomised controlled muticenter trial[J].Trials, 2011, 12 (1) :73.
[2]	[2] MARIK P E, ZALOGA G P.Early enteral nutrtion in acutelly patients:A system riview[J].critical care medicine, 2001, 29 (12) :2264-2270.
[3]	[3]PETROV M S, PYLYPCHUK R D.A systematic review on the timing of artificial nutrition in acute pancreatitis[J].British Journal of Nutrition, 2009, 101 (6) :787-793.
[4]	[4]MARJOLEIN V, MARCO P.Relationship of interleukin-6and tumor necrosis factor-a with muscle mass and muscle strength in elderly men and women:The health ABC study[J].Journal of Gerontology:Medical Scicence, 2002, 57 (5) :M326-M332.
[5]	[5]SCHNEIDER H, BOYLE N.Acute severe pancreatitis and multiple organ failure:total parenteral nutrition is still required in a proportion of patients[J].British Journal of Surgery, 2000, 87 (3) :362.
[6]	[6]PETROV M S, EMELYANOV NVE.Systematic review:nutritional support in acute pancreatitis[J].Alimentary Pharmacology and Therapeutics, 2008, 28 (6) :704-712.
[7]	[7]YOUNG A M, KIDSTON S.Malnutrition screening tool:comparison against two validated nutrition assessment methods in older medical inpatients[J].Nutrition, 2013, 29 (1) :101-106.
[8]	[8]MCCLAVE S A, ROBERT G.Guideline for the provision and assessment of nutrition support therapy in the adult criticallyⅢpatien[J].Journal of parenteral and eternal nutrition, 2009, 33 (3) :277-316.
[9]	[9]ECKERWALL G E, TINSTEDT BBA.Immidate oral feeding in patient with mild acute pancreatitis is safe and may accelerate recovery-A randomized clinical study[J].Clinical nutrition, 2007, 26 (6) :758-763.
[10]叶任高, 陆再英.内科学[M].第6版.北京:人民卫生出版社, 2004:469.
[11]	[11]NATHENS A B, CURTIS J R.Management of the critically ill patient with severe acute pancreatitis[J].Crit Care Med, 2005, 14 (2) :148-150.
[12]	[12]HASIBEDER W R, TORGERSEN.Critical care of the patient with acute pancreatitis[J].Anaesthesia&Intensive Care, 2009, 37 (2) :190-206.
[13]	[13]GROTZ MRW, DETCH E A.Intestinal cytokine response after gut ischemia:Role of gut barrier failure[J].Annals of surgery, 1999, 229 (4) :478-486.
[14]	[14]ALVERDY J B, CHANG E B.The re-emerging role of intestinal microflora in critical illness and inflammation:Why the gut hypothesis of sepsis syndrome will not go away[J].Journal leukocyte biology, 2008, 83 (3) :461-466.
[15]	[15]HONG S, QIANG N.Correlations between the levels of acute infection markers and serum albumin in elderly patients with hip fracture[J].Aging clinical and experimental research, 2017, 29 (3) 29:435-441.
[16]	[16]PAUL E M, GARY P Z.Early Enteral Nutrition In Acutely Ill Patients:A systematic review[J].Crit Care Med, 2001, 29 (12) :2264-2270.
[17]	[17]JUN-HUI L, CAI J W.Prospective study of nasal jejunal tube early enteral nutrition in the treatment of severe acute pancreatitis[J].China Modern Medicine, 2016, 1 (12) :421-429.
[18]	[18]CALABRO P, CHANG W D.Release of C-reactive protein in response to inflammatory cytokines by human adipocytes:Linking obesity to vascular inflammation[J].Journal of the American College of Cardiology, 2005, 46 (6) :1112-1113.
[19]	[19]DEITCH E D.Gut-origin sepsis:Evolution of a concept[J].The Surgeon, 2012, 10 (6) :350-356.

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