Evaluation of Arterial Elasticity, Left Ventricular Function and Correlation by 256-slice Spiral CT in Patients with Aortic Dissection

Du Zi Hong; Sun Yong

Article Contents

Article Navigation > Journal of Kunming Medical University > 2018 > 39(05): 50-55

Du Zi Hong , Sun Yong . Evaluation of Arterial Elasticity, Left Ventricular Function and Correlation by 256-slice Spiral CT in Patients with Aortic Dissection[J]. Journal of Kunming Medical University, 2018, 39(05): 50-55.

Citation:

Du Zi Hong , Sun Yong . Evaluation of Arterial Elasticity, Left Ventricular Function and Correlation by 256-slice Spiral CT in Patients with Aortic Dissection[J]. Journal of Kunming Medical University, 2018, 39(05): 50-55.

Citation:

PDF( 1098 KB)

Evaluation of Arterial Elasticity, Left Ventricular Function and Correlation by 256-slice Spiral CT in Patients with Aortic Dissection

Du Zi Hong ,
Sun Yong

Funds:

基金：云南省应用基础研究计划基金资助项目 (U0120150395);

Received Date: 2017-10-14

Abstract

Abstract

Objective Using the function of 256-layer i CT in the determination of cardiac function and arterial elasticity index, to compare the arterial elasticity, left ventricular function and their correlation between patients with aortic dissection and non-dissected controls, and to provide a reference for the clinical treatment of patients with aortic dissection. Me thods This study selected 36 cases in our emergency department, with chest, back or abdominal pain, whose clinical symptoms were highly suggestive of aortic dissection, and plain or enhanced diagnosis confirmed aortic dissection as a case group. At the same time, we randomly selected 40 cases without aortic dissection as the control group. All subjects underwent CTA one-stop scanning and measurement of elastic and cardiac function at the same level. According to the measurement results, the arterial elasticity indexes and the measured cardiac function of the case group and the control group were evaluated and compared so that to evaluate the arterial elasticity and its correlation with left ventricular function in patients with aortic dissection.Re s ults patients' s arterial expansion and compliance in patients with aortic dissection were significantly lower than the control group (P <0.05) . The mean diameter change rate and stiffness of the patients with dissection were significantly lower than those in the control group (P>0.05) . The difference was not statistically significant. The mean stiffness in patients with aortic dissection was significantly higher than non-aortic dissection patients. In patients with aortic dissection, the mean arterial diameter change rate, expandability and arterial stiffness showed a highly negative correlation. There was no significant correlation between arterial elasticity index and cardiac function in patients with Stanford type A and Stanford type B aortic dissection. There was no significant correlation between each elasticity index and cardiac function in the control group (r <0.3) . Conclus ion CTA one-stop scan can be used as an important measure of arterial elasticity, cardiac function and other parameters in patients with aortic dissection. Significantly lower aortic expansion and compliance, increased stiffness, insignificant changes in cardiac function, and insignificant correlation between cardiac function and each elasticity index in patients with early aortic dissection all have a clinical significance.
- Arterial dissection,
- Arterial elasticity,
- Cardiac function,
- Spiral CT,
- Correlation

FullText(HTML)

References(13)

References

[1]陈阿梅, 谢佳均, 徐向东, 等.320排螺旋CT评估升主动脉弹性与冠状动脉狭窄的相关性[J].中国CT和MRI杂志, 2017, 15 (08) :69-72.
[2]李宁.DSCT在动脉弹性功能评估中的应用价值研究[D].济南:山东大学博士论文, 2012.
[3]	[3] LUDERS F, FISCHBACH R, SEIFARTH H, et al.Dual-source computed tomography:effect on regional and global left ventricular function assessment compared to magnetic resonance imaging[J].Rofo, 2009, 1819 (10) :962-969.
[4]	[4]WAI B, THAI W E, BROWN H, et al.Novel phase-base noise reduction strategy for quantifiction of left ventricular function and mass assessment by cardiac CT:comparison with cardiac magnetic resonance[J].Eur J Radiol, 2013, 82 (8) :e337-e341.
[5]王伟, 郭伟.主动脉弹性的研究现状[J].医疗装备, 2016, 29 (09) :191-194.
[6]胡小平, 王志维, 邓宏平, 等.Fibulin-5在主动脉夹层血管壁中表达异常[J].现代生物医学进展, 2015, 15 (32) :6248-6221.
[7]戚悠飞, 舒畅, 罗明尧, 等.主动脉夹层患者升主动脉中层弹性蛋白与弹力纤维的变化[J].中国普通外科杂志, 2017, 26 (6) :729-734.
[8]	[8]MCENIERY, CARMEL M, MCDONNELL, et al.Aortic calcification is associated with aortic stiffness and isolated systolic hypertension in healthy individuals[J].Hypertension, 2009, 53 (03) :524-531.
[9]邓满红, 姚德惠, 李婧, 等.320排CT在评价左心功能中的研究[J].医学影像学杂志, 2015, 25 (03) :434-436.
[10]	[10] CORNFELD, DANIEL, ISRAEL, et al.Impact of adaptive statistical iterative reconstruction (ASIR) on radiation dose and image quality in aortic dissection studies:a qualitative and quantitative analysis[J].AJR Am J Roentgenol, 2011, 196 (03) :336-340.
[11]	[11] SCHLICHT M S, KHANAFER K, DUPREY A P, et al.Experimental foundation for in vivo measurement of the elasticity of the aorta in computed tomography angiography[J].Eur J Vasc Endovasc Surg, 2013, 46 (04) :447-452.
[12]	[12] LANDENHED, MAYA, ENGSTROM, et al.Risk profiles for aortic dissection and ruptured or surgically treated aneurysms:a prospective cohort study[J].J Am Heart Assoc, 2015, 4 (01) :e001513
[13]	[13]KIM, JUNGSIL, HONG, et al.Longitudinal differences in the mechanical properties of the thoracic aorta depend on circumferential regions[J].J Biomed Mater Res A, 2012, 101 (05) :1525-1529.

Relative Articles(20)

Relative Articles

[1]	Weili LI, Danhua RU, Dan XIE, Jing ZHANG, Ya CHANG, Zhaoxin YANG. Correlation between Serum IL-10，CTL and EB Virus Associated Infectious Mononucleosis Complicated with Liver Damage in Children. Journal of Kunming Medical University, 2025, 47(): 1-8.
[2]	Xinyi SHI, Xiaoni CHONG, Mei LU. Diagnostic Value of Serum sC5b-9，5-HT，and Peripheral Blood C1q mRNA Level Changes on Cognitive Function Impairment in Patients with Bipolar Disorder during Manic Episodes. Journal of Kunming Medical University, 2025, 46(6): 127-132. doi: 10.12259/j.issn.2095-610X.S20250616
[3]	Ruicheng LI, Huarong JING, Yin WU, Ziqi LIN, Peipei ZHAO, Shan WEI, Tian WANG. Construction of a Predictive Model for High-Risk ISS Stage in Newly Diagnosed Multiple Myeloma Patients Based on Coagulation Indicators. Journal of Kunming Medical University, 2025, 47(): 1-6.
[4]	Peng DING, Jia LI, Xiaodan ZHAO, Jie ZHAO, Changrong MIAO. Protective Effect of MiR-193a-5p on Cardiac Function in Rats with Chronic Heart Failure by Regulating IL-33/ST2 Signaling Pathway. Journal of Kunming Medical University, 2025, 46(5): 48-54. doi: 10.12259/j.issn.2095-610X.S20250506
[5]	Wenmin CHEN, Jinghong PI, Xintong FU, Yueqing CHEN, Hua LI, Zheng JIA. A Study on the Application of the Timing-It-Right Framework Combined with Phase I Cardiac Rehabilitation Model in Patients Undergoing Transcatheter Aortic Valve Replacement. Journal of Kunming Medical University, 2025, 46(11): 172-178. doi: 10.12259/j.issn.2095-610X.S20251121
[6]	Qianru XU, Songwu DONG, Rongyan Jiang. Efficacy of Sacubitril/Valsartan in the Treatment of Patients with Coronary Artery Disease Complicated by Heart Failure. Journal of Kunming Medical University, 2025, 47(): 1-8.
[7]	Yanfen MA, Sasa LIU, Jian HU, Depei CAI, Yongfeng QIAO, Xiaoqin WANG. Analysis of the Predictive Effects of Lipid Metabolism and Liver Function Indicators on Prediabetes. Journal of Kunming Medical University, 2024, 45(12): 153-159. doi: 10.12259/j.issn.2095-610X.S20241222
[8]	Xiaohua LU, Hongxin YUAN. The Analysis of the Correlation between BTLA，CTLA-4 Gene Polymorphisms and the Efficacy and Prognosis of TACE Combined Targeted Therapy for Liver Cancer. Journal of Kunming Medical University, 2023, 44(9): 126-135. doi: 10.12259/j.issn.2095-610X.S20230927
[9]	Yan QIU, Yinli WANG, Mengmeng YANG, Liangmin GUO, Longhui YUAN. Association between MPV，PDW，PCT and Cardiac Function in Patients with Pulmonary Hypertension. Journal of Kunming Medical University, 2023, 44(12): 121-126. doi: 10.12259/j.issn.2095-610X.S20231219
[10]	Yanfen MA, Jian HU, Depei CAI, Yongfeng QIAO, Xiaoqin WANG. Correlation between Serum Gamma-glutamyl Transferase Level and Blood Lipid Indexes in 3137 Checkup Population. Journal of Kunming Medical University, 2022, 43(10): 115-121. doi: 10.12259/j.issn.2095-610X.S20221001
[11]	Hai-ping ZHANG, Shu-juan YANG, Li-xia YANG, Zhao-juan RUAN, Rui-wei GUO. Effect of Hyperhomocysteinemia on Cardiac Function and Mortality of Patients with Acute Myocardial Infarction Concomitant Hypertension underwent Primary Percutaneous Coronary Intervention after 6 Months. Journal of Kunming Medical University, 2021, 42(3): 73-78. doi: 10.12259/j.issn.2095-610X.S20210319
[12]	Wei-wen WANG, De-xia LI, Jie ZHANG, Lin LI. Correlation Between Serum Soluble ST2 and Cardiac Remodeling in Patients with Heart Failure with Reduced Ejection Fraction. Journal of Kunming Medical University, 2021, 42(8): 71-77. doi: 10.12259/j.issn.2095-610X.S20210813
[13]	Xin WU, Yun LI, Pin-fei ZOU, Mei-ling LI, Yong-bin PU. The Detection Rate of Musculoskeletal Ultrasound in Patients with Rheumatic Knee Arthritis and Its Correlation with Knee Function. Journal of Kunming Medical University, 2021, 42(8): 78-82. doi: 10.12259/j.issn.2095-610X.S20210814
[14]	Mei CEN, Dan-dan YUAN, Ming JIN, Xue-lian LIU, Wei-wei SHANG. Effect of Cardiac Exercise Rehabilitation on Cardiac Function and Quality of Life in Patients with Hypertensive Heart Disease Complicated with Heart Failure. Journal of Kunming Medical University, 2021, 42(5): 107-113. doi: 10.12259/j.issn.2095-610X.S20210520
[15]	Liu Shi Jie . . Journal of Kunming Medical University,
[16]	Wang Yu . . Journal of Kunming Medical University,
[17]	Han Xiao Feng . . Journal of Kunming Medical University,
[18]	Zheng Hong Mei . . Journal of Kunming Medical University,
[19]	Zhao Jin You . . Journal of Kunming Medical University,
[20]	Zhang Ti Ling . . Journal of Kunming Medical University,