Pyrethroid Exposure and Related Factors among Pregnant Women in the First Trimester in Rural Yunnan Province, China

Sun Lin; Xiao Xia; Li Yan; Yang Si Wei; Xu Qing Hua; Ma Rui; Wu Jie; Zhang Chao; Guo Guang Ping

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Sun Lin , Xiao Xia , Li Yan , Yang Si Wei , Xu Qing Hua , Ma Rui , Wu Jie , Zhang Chao , Guo Guang Ping . Pyrethroid Exposure and Related Factors among Pregnant Women in the First Trimester in Rural Yunnan Province, China[J]. Journal of Kunming Medical University, 2018, 39(06): 39-43.

Citation:

Sun Lin , Xiao Xia , Li Yan , Yang Si Wei , Xu Qing Hua , Ma Rui , Wu Jie , Zhang Chao , Guo Guang Ping . Pyrethroid Exposure and Related Factors among Pregnant Women in the First Trimester in Rural Yunnan Province, China[J]. Journal of Kunming Medical University, 2018, 39(06): 39-43.

Citation:

Sun Lin , Xiao Xia , Li Yan , Yang Si Wei , Xu Qing Hua , Ma Rui , Wu Jie , Zhang Chao , Guo Guang Ping . Pyrethroid Exposure and Related Factors among Pregnant Women in the First Trimester in Rural Yunnan Province, China[J]. Journal of Kunming Medical University, 2018, 39(06): 39-43.

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Pyrethroid Exposure and Related Factors among Pregnant Women in the First Trimester in Rural Yunnan Province, China

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基金：国家自然科学基金资助项目 (81673186); 云南公共卫生与疾病防控协同创新中心基金资助项目 (2014YNPHXT17);

Received Date: 2018-02-14

Abstract

Abstract

Objective To investigate the level and relevant factors of pyrethroid pesticide exposure among pregnant women during the first trimester in rural areas of Yunnan province, and to provide basic data for further study and provide a basis for the formulation of intervention measures to reduce exposure.Me thods According to the birth cohort of rural Yunnan built in 2014, pregnant women in the first trimester were recruited in two townships of an agricultural county who were confirmed pregnant and continued pregnancy in antenatal clinics. The concentration of the metabolites of the pesticides in the urine of women was determined by super high performance liquid chromatography and the contact status of pyrethroid pesticides was analyzed using a questionnaire survey.Re s ults A total of 419 women in the first trimester were surveyed and 94.51% of women detected at least one of the pyrethroid metabolites, among which the detection rates of 3-Phenoxybenzoic acid (3-PBA) , cis-/trans-3- (2, 2-Dichloroethenyl) -2, 2-dimethyl-cyclopropanecarboxylate (cis-/trans-DCCA) and 4-fluoro-3-phenoxybenzoic acid (4-F-3-PBA) were 79.47%, 62.05% and 24.58%, and the median concentrations were3.53 ng/m L, 14.80 ng/m L and less than the minimum detection limit 0.4 ng/m L.Only 12 people (2.95%) reported that they had exposure to pesticides.Self-reported exposure rate was not consistent with the actual exposure rate.Multivariate linear regression analysis showed that the season was a factor affecting the level of three metabolites in women in the first trimester. Higher lever was found in women in spring (t=2.147, P=0.032) , summer (t=2.144, P=0.035) and winter (t=2.453, P=0.015) compared to those in autumn.Conclus ion Pyrethroid pesticides were widely exposed in the pregnant women in rural areas of Yunnan province. Some women have higher exposure level, which is related to the season.
- First trimester,
- Pyrethroid pesticides,
- Exposure,
- Rural area

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References(13)

References

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