Correlation study of the Predictive Value of Beta-trace Protein to Contrast-induced Nephropathy after Coronary Intervention

Miao Wen Qing; Wang Yu; Yang Jun; Zhang Yi Hong; Tian Qing; Duan Hui Xian; Zhao Zhong Wen; Wang Yan; Yang Xing Hu

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Article Navigation > Journal of Kunming Medical University > 2018 > 39(07): 114-118

Miao Wen Qing , Wang Yu , Yang Jun , Zhang Yi Hong , Tian Qing , Duan Hui Xian , Zhao Zhong Wen , Wang Yan , Yang Xing Hu . Correlation study of the Predictive Value of Beta-trace Protein to Contrast-induced Nephropathy after Coronary Intervention[J]. Journal of Kunming Medical University, 2018, 39(07): 114-118.

Citation:

Miao Wen Qing , Wang Yu , Yang Jun , Zhang Yi Hong , Tian Qing , Duan Hui Xian , Zhao Zhong Wen , Wang Yan , Yang Xing Hu . Correlation study of the Predictive Value of Beta-trace Protein to Contrast-induced Nephropathy after Coronary Intervention[J]. Journal of Kunming Medical University, 2018, 39(07): 114-118.

Citation:

Miao Wen Qing , Wang Yu , Yang Jun , Zhang Yi Hong , Tian Qing , Duan Hui Xian , Zhao Zhong Wen , Wang Yan , Yang Xing Hu . Correlation study of the Predictive Value of Beta-trace Protein to Contrast-induced Nephropathy after Coronary Intervention[J]. Journal of Kunming Medical University, 2018, 39(07): 114-118.

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Correlation study of the Predictive Value of Beta-trace Protein to Contrast-induced Nephropathy after Coronary Intervention

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基金：北京力生心血管健康基金会领航基金资助基目 (LHJJ20158821);

Received Date: 2018-03-19

Abstract

Abstract

Objective To investigate the correlation of the concentration of blood/urine beta-trace protein (βTP) in the prediction of contrast-induced nephropathy. Methods This study enrolled 88 patients with interventional diagnosis or treatment from september to December 2016 in the first hospital of Kunming and the patients were divided into two groups: CIN group (nn = 7) and non-CIN group (n = 81) . The concentration of blood/urine βTP was measured by ELISA method and the results was analysed with SPSS.Re s ults There was significant difference in the level of blood βTP before the operation, 2 h after operation and 24 h after the operation between the two groups (P<0.05) , so was that in the level of urine βTP (P<0.05) . The area under ROC curve (AUC) of blood βTP 2 h after the operation was 0.761, the diagnostic value was 567.568, and the sensitivity and specificity were 71.4% and 81.5% while the area of ROC curve (AUC) of urine βTP 2 h after the operation was0.967, the diagnostic value was 1428.893, and the sensitivity and specificity were 100% and 97.5%.Conclus ion The concentration of blood/urine βTP 2 h after the operation can be used as a new indicator to predict contrast-induced nephropathy. The sensitivity and specificity of urine βTP is better than those of blood βTP, and urine samples are easier to be collected than blood samples.
- Beta-trace protein,
- Coronary heart disease,
- Contrast-induced nephropathy

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References(11)

References

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