Genetic Polymorphism of 19 Autosomal STR Loci in Yunnan Yi Popolation

Yang Shuo; Jiang Yan Ling; Fang Bao Xiong; Ji Ai Cen; Zhang Shou Xun; Zhang Xiu Feng; Zhang Nin; Zhao Fei; Zhong Shu Rong

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Article Navigation > Journal of Kunming Medical University > 2019 > 40(03): 120-125

Yang Shuo , Jiang Yan Ling , Fang Bao Xiong , Ji Ai Cen , Zhang Shou Xun , Zhang Xiu Feng , Zhang Nin , Zhao Fei , Zhong Shu Rong . Genetic Polymorphism of 19 Autosomal STR Loci in Yunnan Yi Popolation[J]. Journal of Kunming Medical University, 2019, 40(03): 120-125.

Citation:

Yang Shuo , Jiang Yan Ling , Fang Bao Xiong , Ji Ai Cen , Zhang Shou Xun , Zhang Xiu Feng , Zhang Nin , Zhao Fei , Zhong Shu Rong . Genetic Polymorphism of 19 Autosomal STR Loci in Yunnan Yi Popolation[J]. Journal of Kunming Medical University, 2019, 40(03): 120-125.

Citation:

Yang Shuo , Jiang Yan Ling , Fang Bao Xiong , Ji Ai Cen , Zhang Shou Xun , Zhang Xiu Feng , Zhang Nin , Zhao Fei , Zhong Shu Rong . Genetic Polymorphism of 19 Autosomal STR Loci in Yunnan Yi Popolation[J]. Journal of Kunming Medical University, 2019, 40(03): 120-125.

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Genetic Polymorphism of 19 Autosomal STR Loci in Yunnan Yi Popolation

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基金：国家自然科学基金资助项目 (81660232, 81000577); 云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目 (2015FB011); 昆明医科大学百名中青年学术技术骨干项目 (60117190413) ;昆明医科大学大学生创新性试验计划项目 (CX201416, CX201544, CX201654, 601162023);

Received Date: 2018-09-04

Abstract

Abstract

Objective To study the genetic polymorphisms of 19 autosomal STR loci in 215 healthy unrelated individuals of Yunnan Yi population, calculate population genetic parameters, and establish genetic basis data of Yunnan Yi population, and provide scientific basis for forensic material identification and individual identification.Methods The sample DNA was extracted by Chelex-100 method, amplified by Power Plex 21 System kit, and the PCR composite amplification product was analyzed by ABI 3130 XL automatic genetic analyzer. STR was performed with ABI Gene Mapper v3.2 software. Genotyping analysis, statistical analysis of forensic genetic parameters and Hardy-Weinberg equilibrium test using Modified-Powerstates software. Results A total of 203 alleles and 666 genotypes were detected. Except D1 S1656, D5 S818, D12 S391, the genotype distribution accorded with Hardy-Weinberg equilibrium law (P > 0.05) , the cumulative non-parent exclusion rate (CPE) was 0.999 999 907, and the cumulative personal recognition ability (TDP) was 0.999 999 999 999 999. 999 9999. Conclusion The 19 autosomal loci have high polymorphism and good individual recognition ability in Yunnan Yi population, and can provide scientific genetic basic data for forensic individual identification and paternity identification.
- STR,
- Yunnan Yi population,
- Genetic polymorphism

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References(16)

References

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