Advances in Synovitis Associated with Osteoarthritis

Yi Nan Xing; Liang Qing Qing; Zhang Wei Qiang; Shi Qi; Wang Yong Jun; Xu Hao; Zhang Ting

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Yi Nan Xing , Liang Qing Qing , Zhang Wei Qiang , Shi Qi , Wang Yong Jun , Xu Hao , Zhang Ting . Advances in Synovitis Associated with Osteoarthritis[J]. Journal of Kunming Medical University, 2019, 40(03): 136-139.

Citation:

Yi Nan Xing , Liang Qing Qing , Zhang Wei Qiang , Shi Qi , Wang Yong Jun , Xu Hao , Zhang Ting . Advances in Synovitis Associated with Osteoarthritis[J]. Journal of Kunming Medical University, 2019, 40(03): 136-139.

Citation:

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Advances in Synovitis Associated with Osteoarthritis

Yi Nan Xing ^1,2,3,
Liang Qing Qing ^1,2,3,
Zhang Wei Qiang ^1,2,3,
Shi Qi ^1,2,3,
Wang Yong Jun ^1,2,3,
Xu Hao ^1,2,3,
Zhang Ting ^1,2,3

Funds:

基金：国家自然科学基金优秀青年科学基金项目 (81822050) ;国家自然科学基金面上项目 (81873321, 81673990) ;国家自然科学基金重点项目 (81330085, 81730107); 上海市卫生和计划生育委员会中医药科研课题项目 (2018JP014); 促进市级医院临床技能与临床创新三年行动计划 (16CR1017A); 上海市中医慢病 (恶性肿瘤、骨退行性病变) 临床医学中心 (2017ZZ01010); 上海市长宁区卫生与计划生育委员会“光华卓越PI工程 (2016-01, 2016-06);

Received Date: 2018-12-03

Abstract

Abstract

Osteoarthritis (OA) is a common chronic degenerative disease affecting synovial joints (knee, hip, distal finger, spinal joint) . Lesions often affect the entire joint tissue, with the degradation of articular cartilage, joint bone Ankle formation and synovial lesions are characteristic. Most of the previous research and treatment focuses on articular cartilage lesions, more and more studies have shown that inflammatory lesions of the synovial membrane play an important role in the whole course of osteoarthritis, synovial inflammation and induction of inflammatory factors associated with synovium. The degradation and destruction of articular cartilage promotes the development of osteoarthritis. Synovial lesions play an important role in the development of osteoarthritis. Therefore, synovial inflammation can be a key target for the treatment of osteoarthritis.
- Osteoarthritis,
- Synovitis,
- Pathophysiology,
- Epidemiology

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References(24)

References

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