Expression of MCM7 Protein during the Spermatogenesis of Artificially Domesticated Tree Shrew

Guang-yong HE; Jian TANG; Fang YANG; Zhong-yi QIAN; Yu-ling YANG; Lan LUO

doi:10.12259/j.issn.2095-610X.S20210112

Volume 42 Issue 1

Jan. 2021

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Guang-yong HE, Jian TANG, Fang YANG, Zhong-yi QIAN, Yu-ling YANG, Lan LUO. Expression of MCM7 Protein during the Spermatogenesis of Artificially Domesticated Tree Shrew[J]. Journal of Kunming Medical University, 2021, 42(1): 1-5. doi: 10.12259/j.issn.2095-610X.S20210112

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Expression of MCM7 Protein during the Spermatogenesis of Artificially Domesticated Tree Shrew

doi: 10.12259/j.issn.2095-610X.S20210112

Guang-yong HE^{1, 2},
Jian TANG^{1, 3},
Fang YANG¹,
Zhong-yi QIAN¹,
Yu-ling YANG¹,
Lan LUO^{1
,
,}

1.
School of Basic Medical Sciences，Kunming Medical University，Kunming Yunnan 650500，China
2.
Clinical Laboratory，Kunming Maternal and Child Health Care Hospital，Kunming Yunnan 650041，China
3.
Dept.of Medical Genetics and Prenatal Diagnosis，Kunming Maternal and Child Health Hospital，Kunming Yunnan 650031，China

Received Date: 2020-08-06
Available Online: 2021-01-26
Publish Date: 2021-01-26

Abstract

Abstract

Objective To study the expression characteristics of MCM7 protein during spermatogenesis of artificially domesticated tree shrews and whether there are seasonal differences in its expression, so as to provide basic experimental data for reproductive research using tree shrews as animal models. Methods 12 groups of adult male artificially domesticated tree shrews testis tissues of different months were used as the materials and immunohistochemical detection of MCM7 protein was performed on the paraffin tissue sections. Results MCM7 protein was expressed in spermatogonia and some primary spermatocyte of the testes in artificially domesticated tree shrews. Compared with the other months in the whole year, the positive cell rate of MCM7 protein was significantly different in February and March （P < 0.05）. Conclusions MCM7 protein may play a role in the DNA replication of spermatogonia and primary spermatocytes during the spermatogenesis of artificially domesticated tree shrews, and there was seasonal difference in the activity of MCM7 protein expression.
- Artificially domesticated tree shrew,
- Spermatogenesis,
- MCM7 protein

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References(12)

References

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