Expression of Long Non-coding RNA APTR，HEIH，FAS-ASA1，FAM83H-AS1，DICER1-AS1，PR-lncRNA in Lung Cancer

Teng-fei ZHANG; Yue-feng HE; Lei ZHANG; Li ZHANG; Kai-yun YANG; Lian-qing LIU; Hui TAN

doi:10.12259/j.issn.2095-610X.S20210409

Volume 42 Issue 4

Apr. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(4): 49-52

Teng-fei ZHANG, Yue-feng HE, Lei ZHANG, Li ZHANG, Kai-yun YANG, Lian-qing LIU, Hui TAN. Expression of Long Non-coding RNA APTR，HEIH，FAS-ASA1，FAM83H-AS1，DICER1-AS1，PR-lncRNA in Lung Cancer[J]. Journal of Kunming Medical University, 2021, 42(4): 49-52. doi: 10.12259/j.issn.2095-610X.S20210409

Citation:

Teng-fei ZHANG, Yue-feng HE, Lei ZHANG, Li ZHANG, Kai-yun YANG, Lian-qing LIU, Hui TAN. Expression of Long Non-coding RNA APTR，HEIH，FAS-ASA1，FAM83H-AS1，DICER1-AS1，PR-lncRNA in Lung Cancer[J]. Journal of Kunming Medical University, 2021, 42(4): 49-52. doi: 10.12259/j.issn.2095-610X.S20210409

Citation:

Teng-fei ZHANG, Yue-feng HE, Lei ZHANG, Li ZHANG, Kai-yun YANG, Lian-qing LIU, Hui TAN. Expression of Long Non-coding RNA APTR，HEIH，FAS-ASA1，FAM83H-AS1，DICER1-AS1，PR-lncRNA in Lung Cancer[J]. Journal of Kunming Medical University, 2021, 42(4): 49-52. doi: 10.12259/j.issn.2095-610X.S20210409

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Expression of Long Non-coding RNA APTR，HEIH，FAS-ASA1，FAM83H-AS1，DICER1-AS1，PR-lncRNA in Lung Cancer

doi: 10.12259/j.issn.2095-610X.S20210409

1.
Dept. of Thoracic Surgery，The 3rd Affiliated Hospital of Kunming Medical University，Kunming Yunnan，650118
2.
School of Public Health，Kunming Medical University，Kunming Yunnan 650500，China

Received Date: 2020-12-28
Publish Date: 2021-04-01

Abstract

Abstract

Objective To investigate the expression of long non-coding RNA （IncRNA） APTR, HEIH, FAS-ASA1, FAM83H-AS1, DICER1-AS1 and PR-lncRNA in lung cancer patients. METHODS Total RNA was extracted by TRI Z O L from cancer tissues, adjacent normal tissues and lymph node metastases of lung cancer patients in the Third Affiliated Hospital of Kunming Medical University. The relative RNA expression of each gene was detected by SYBR GR e e N real-time quantitative fluorescence PCR. RESULTS The expression of APTR was increased in lymphoid tissues （P < 0.05）, the expression of HEIH was decreased in lymphoid tissues （P < 0.05）, and the expression of FAM83H-AS1 and PR-lncRNA were increased in lung cancer tissues （P < 0.05）. Conclusion Increased expression of APTR in lymphoid tissue may promote lymph node metastasis of lung cancer; increased expression of FAM83H-AS1 and PR-lncRNA in cancer tissue may promote the occurrence and development of lung cancer.
- Lung cancer,
- LncRNA,
- Expression,
- Oncogene

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References(20)

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