Volume 42 Issue 5
May  2021
Turn off MathJax
Article Contents
Wang-bin XU, Dong-mei DAI, Mei-e HE, LI Le-yun XIAO, Fei WANG, Lei YANG, Kun TANG. Changes of the Difference between Hematocrit and Albumin in the Course of Secondary Abdominal Infection[J]. Journal of Kunming Medical University, 2021, 42(5): 101-106. doi: 10.12259/j.issn.2095-610X.S20210519
Citation: Wang-bin XU, Dong-mei DAI, Mei-e HE, LI Le-yun XIAO, Fei WANG, Lei YANG, Kun TANG. Changes of the Difference between Hematocrit and Albumin in the Course of Secondary Abdominal Infection[J]. Journal of Kunming Medical University, 2021, 42(5): 101-106. doi: 10.12259/j.issn.2095-610X.S20210519

Changes of the Difference between Hematocrit and Albumin in the Course of Secondary Abdominal Infection

doi: 10.12259/j.issn.2095-610X.S20210519
  • Received Date: 2021-01-08
  • Publish Date: 2021-05-25
  •   Objective   To provide the certain guidance for the accurate treatment of patients with abdominal infection by observing the changes of the difference between HCT and ALB in the treatment of patients with abdominal infection.   Methods   A total of 106 patients with various abdominal infection treated in the First Affiliated Hospital of Kunming Medical University from January 2018 to December 2018 were selected and divided into 7 groups (n = 106) according to the operation time: preoperative, postoperative 12 h, postoperative 1 day, postoperative 2 days, postoperative 7 days, postoperative 14 days and postoperative 21 days. Gender and age of patients were recorded. The hematocrit and plasma albumin of patients at each time point above were collected, and the HCT-ALB difference was calculated. According to the clinical outcome, they were divided into the postoperative improvement group and the death group. The difference of HCT, ALB and HCT-ALB in each group was compared.   Results   Compared with those before the surgery, HCT and ALB decreased and HCT-ALB increased 12 h, 1 day, 2 days and 7 days after the surgery (P < 0.05). Compared with those before the operation, HCT and ALB decreased 14 days after the operation ( P < 0.05), but there was no significant difference in HCT-ALB ( P > 0.05). Compared with the improved group, the age of patients in the death group increased ( P < 0.05), and the preoperative HCT-ALB increased ( P < 0.05).   Conclusion   Capillary leakage is aggravated in patients with celiac infection after the surgical treatment, and the pathological process lasts for more than 7 days, and the capillaries of the dead are more leaky.
  • loading
  • [1]
    王鹏文,张文彬. 腹腔灌洗治疗重症腹腔感染65例分析[J]. 中国误诊学杂志,2002,2(10):1565-1565. doi: 10.3969/j.issn.1009-6647.2002.10.121
    [2]
    Petersen M W,Perner A,Ravn F,et al. Untargeted antifungal therapy in adult patients with complicated intra‐abdominal infection:A systematic review[J]. Acta Anaesthesiologica Scandinavica,2018,62(1):6-18. doi: 10.1111/aas.13031
    [3]
    Dai D M,Wang D,Hu D,et al. Difference in hematocrit and plasma albumin levels as an additional biomarker in the diagnosis of infectious disease[J]. Arch Med Sci,2020,16(3):522-530. doi: 10.5114/aoms.2019.86898
    [4]
    Dai D M,Cao J,Yang H M,et al. Hematocrit and plasma albumin levels difference may be a potential biomarker to discriminate preeclampsia and eclampsia in patients with hypertensive disorders of pregnancy[J]. Clinica Chimica Acta,2017,464(1):218-222.
    [5]
    代冬梅,唐坤,许汪斌,等. 系统性毛细血管渗漏综合征病程中血细胞比容与血浆白蛋白差值的变化:系统评价分析[J]. 中华危重病急救医学,2018,30(10):920-924. doi: 10.3760/cma.j.issn.2095-4352.2018.10.002
    [6]
    许汪斌,胡锐,王雨平,等. 白蛋白差值用于鉴别失血性休克和感染性休克的可行性研究[J].中华危重病急救医学,2018,30(12):1137-1140. [J]. 中华危重病急救医学,2019,31(12):1527-153. doi: 10.3760/cma.j.issn.2095-4352.2019.12.018
    [7]
    代冬梅,胡锐,许汪斌,等. 血细胞比容与白蛋白差值用于鉴别失血性休克和感染性休克的可行性研究[J]. 中华危重病急救医学,2018,30(12):1137-1140. doi: 10.3760/cma.j.issn.2095-4352.2018.12.007
    [8]
    Marschner,Clara B,Wiinberg,et al. The influence of inflammation and hematocrit on clot strength in canine thromboelastographic hypercoagulability[J]. Journal of Veterinary Emergency and Critical Care,2018,28(1):20-30. doi: 10.1111/vec.12675
    [9]
    杨毅,邱海波. 《2004严重感染和感染性休克治疗指南》系列讲座(4)—糖皮质激素在感染性休克中的应用[J]. 中华危重病急救医学,2004,16(10):582-584. doi: 10.3760/j.issn:1003-0603.2004.10.003
    [10]
    Kasie Fang,Chester L Bowen,John F Kellie,et al. Drug monitoring by volumetric absorptive microsampling:Method development considerations to mitigate hematocrit effects[J]. Bioanalysis,2018,10(4):241-255. doi: 10.4155/bio-2017-0221
    [11]
    Walton Bethany L,Lehmann Marcus,Skorczewski Tyler,et al. Elevated hematocrit enhances platelet accumulation following vascular injury.[J]. Blood,2017,129(18):2537-2546. doi: 10.1182/blood-2016-10-746479
    [12]
    Oberholzer A,Oberholzer C,Moldawer L L. Cytokine signaling:regulation of the immune response in normal and critically ill states[J]. Crit Care Med,2000,28(4 Suppl):3-12.
  • Relative Articles

    [1] Longqiao TAN, Li SHI, Jianfang LIU, Xuemei XIA, Li ZHU, Yushan XU. Correlation between 24-hour Urinary Sodium Excretion,IL-18 Level and Urinary Albumin in Patients with Type 2 Diabetes Mellitus. Journal of Kunming Medical University, 2024, 45(9): 49-55.  doi: 10.12259/j.issn.2095-610X.S20240908
    [2] Ruiting ZHANG, Bin YAN, Zuyan LI, Jinmin SUN, Jin YAO. Relations between Peripheral Blood Blast Clearance Time and Albumin Level at Initial Diagnosis during Induction Chemotherapy and Genetic Mutations and Prognosis in Patients with Acute Myeloid Leukemia. Journal of Kunming Medical University, 2024, 45(8): 117-124.  doi: 10.12259/j.issn.2095-610X.S20240817
    [3] Wei MA, Meihua LI, Jing JIANG, Xingxu LIU, Lifen YANG, Li LI. Advances in the study of heparin-binding protein and serum amyloid A in AECOPD co-infection of the lung. Journal of Kunming Medical University, 2023, 44(2): 172-176.  doi: 10.12259/j.issn.2095-610X.S20230228
    [4] Ji JIA, Siming TAO. Development of A Plasma Osmolality Prediction Model for the Risk of In-hospital Death in Critically Ill Patients with Acute ST-segment Elevation Myocardial Infarction. Journal of Kunming Medical University, 2022, 43(12): 58-65.  doi: 10.12259/j.issn.2095-610X.S20221212
    [5] Li Mei , Xu Wang Bin , Wang Yu Ping , Wang Fei , Dai Dong Mei . . Journal of Kunming Medical University, 2020, 41(03): 62-66.
    [6] Jian-pei SU, Wei-meng TIAN, Jun GU, Mi-yu HE. Association between C-reactive Protein/Albumin Ratio and Long-term Prognosis in Elderly Patients with Heart Failure. Journal of Kunming Medical University, 2020, 41(12): 128-132.  doi: 10.12259/j.issn.2095-610X.S20201236
    [7] Sun Shi Bo , Luo Zhuang , Du Xiao Hua , Yang Jiao , Ye Xiu Lin , Zhang Dong Xian , Yang Wei Min . . Journal of Kunming Medical University, 2019, 40(06): 109-113.
    [8] Chen Xian Wei , Lu Xiang Dong , Wang Yong Feng , Zhao Die Bo , Yang Xu , Wang Wen Xuan , Fan Yan Xin , Zhang Hui , Zhao Bin . . Journal of Kunming Medical University, 2019, 40(06): 76-79.
    [9] Lin Feng . Application of Human Blood Albumin in Patients with Traumatic Fracture. Journal of Kunming Medical University,
    [10] Dai Qing Yuan . . Journal of Kunming Medical University,
    [11] Fei Qiu Yue . . Journal of Kunming Medical University,
    [12] Zhang Chan . . Journal of Kunming Medical University,
    [13] Tang Ai Qun . . Journal of Kunming Medical University,
    [14] Li Fan. . Journal of Kunming Medical University,
    [15] Chen Xiao Hong . . Journal of Kunming Medical University,
    [16] Wang Xing Ning . . Journal of Kunming Medical University,
    [17] Mao Wen Wen . . Journal of Kunming Medical University,
    [18] Zhang Hong . . Journal of Kunming Medical University,
    [19] Du Xing Hua . . Journal of Kunming Medical University,
    [20] . Chromosomal Analysis in Spontaneous Abortion during the First Trimester after Assisted Reproduction Technique Treatment. Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(7)

    Article Metrics

    Article views (3066) PDF downloads(10) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return