Clinical Efficacy of Non-biological Artificial Liver in 112 Patients with Liver Failure

Zhao XIANG; Jin-hui YANG

doi:10.12259/j.issn.2095-610X.S20211034

Volume 42 Issue 12

Dec. 2021

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Zhao XIANG, Jin-hui YANG. Clinical Efficacy of Non-biological Artificial Liver in 112 Patients with Liver Failure[J]. Journal of Kunming Medical University, 2021, 42(12): 140-144. doi: 10.12259/j.issn.2095-610X.S20211034

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Zhao XIANG, Jin-hui YANG. Clinical Efficacy of Non-biological Artificial Liver in 112 Patients with Liver Failure[J]. Journal of Kunming Medical University, 2021, 42(12): 140-144. doi: 10.12259/j.issn.2095-610X.S20211034

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Clinical Efficacy of Non-biological Artificial Liver in 112 Patients with Liver Failure

doi: 10.12259/j.issn.2095-610X.S20211034

Zhao XIANG,
Jin-hui YANG^,

Dept. of Gastroenterology，The 2nd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China

Received Date: 2021-07-22
Available Online: 2021-12-15
Publish Date: 2021-12-15

Abstract

Abstract

Objective To investigate the clinical efficacy of non-biological artificial liver in patients with liver failure. Methods A retrospective analysis of 112 cases of liver failure patients treated with non-biological artificial liver in our hospital from January 2017 to December 2020, to observe the clinical efficacy and influencing factors. Results 112 patients with liver failure had significantly increased ALB, ALT, AST, CHE, TBIL, DBIL, IBIL, and PLT after treatment with non-biological artificial liver. The difference was statistically significant （P < 0.05）. According to non-biological artificial liver treatment, the difference was statistically significant （P < 0.05）. Liver treatment results, 112 patients were divided into improved group （61 cases）, no improvement group （51 cases）, in terms of the overall efficacy of non-biological artificial liver in the treatment of liver failure, AST, TBIL, DBIL, IBIL, PT, INR The MELD value decreased significantly, and the difference was statistically significant （P < 0.05）. Conclusion Non-biological artificial liver can effectively improve the liver function and coagulation function of patients with liver failure, reduce bilirubin, and reduce the mortality of patients. MELD value can be used to guide non-biological artificial liver treatment after evaluating the condition of patients with liver failure.
- Non-biological artificial liver,
- Liver failure,
- Retrospective study,
- MELD value

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