Volume 42 Issue 12
Dec.  2021
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Article Navigation >  Journal of Kunming Medical University  > 2021  >  42(12): 140-144
Yue LU, Changming QIU, Yunli YANG, Zhiguo HUANG, Zhigui LI, Weiqing MA, Na LI. Analgesia of Ultrasound-guided Single-dose Adductor Canal Block with Dexmedetomidine Combined with Ropivacaine after Patella Fracture Surgery in Adults[J]. Journal of Kunming Medical University, 2022, 43(6): 68-73. doi: 10.12259/j.issn.2095-610X.S20220613
Citation: Zhao XIANG, Jin-hui YANG. Clinical Efficacy of Non-biological Artificial Liver in 112 Patients with Liver Failure[J]. Journal of Kunming Medical University, 2021, 42(12): 140-144. doi: 10.12259/j.issn.2095-610X.S20211034
shu

Clinical Efficacy of Non-biological Artificial Liver in 112 Patients with Liver Failure

doi: 10.12259/j.issn.2095-610X.S20211034

  • Dept. of Gastroenterology，The 2nd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China

  • Received Date: 2021-07-22
    Available Online: 2021-12-15
  • Publish Date: 2021-12-15
    Abstract
  •   Objective  To investigate the clinical efficacy of non-biological artificial liver in patients with liver failure.   Methods  A retrospective analysis of 112 cases of liver failure patients treated with non-biological artificial liver in our hospital from January 2017 to December 2020, to observe the clinical efficacy and influencing factors.   Results  112 patients with liver failure had significantly increased ALB, ALT, AST, CHE, TBIL, DBIL, IBIL, and PLT after treatment with non-biological artificial liver. The difference was statistically significant （P < 0.05）. According to non-biological artificial liver treatment, the difference was statistically significant （P < 0.05）. Liver treatment results, 112 patients were divided into improved group （61 cases）, no improvement group （51 cases）, in terms of the overall efficacy of non-biological artificial liver in the treatment of liver failure, AST, TBIL, DBIL, IBIL, PT, INR The MELD value decreased significantly, and the difference was statistically significant （P < 0.05）.  Conclusion  Non-biological artificial liver can effectively improve the liver function and coagulation function of patients with liver failure, reduce bilirubin, and reduce the mortality of patients. MELD value can be used to guide non-biological artificial liver treatment after evaluating the condition of patients with liver failure.
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