Factors Influencing Potential Inappropriate Medication Use in Elderly Patients Based on Beers Criteria 2019 Edition

Lin ZHANG; Sha-sha DONG; Wan-xiong WANG; Hai-fang LI

doi:10.12259/j.issn.2095-610X.S20211234

Volume 42 Issue 12

Dec. 2021

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Lin ZHANG, Sha-sha DONG, Wan-xiong WANG, Hai-fang LI. Factors Influencing Potential Inappropriate Medication Use in Elderly Patients Based on Beers Criteria 2019 Edition[J]. Journal of Kunming Medical University, 2021, 42(12): 145-150. doi: 10.12259/j.issn.2095-610X.S20211234

Citation:

Lin ZHANG, Sha-sha DONG, Wan-xiong WANG, Hai-fang LI. Factors Influencing Potential Inappropriate Medication Use in Elderly Patients Based on Beers Criteria 2019 Edition[J]. Journal of Kunming Medical University, 2021, 42(12): 145-150. doi: 10.12259/j.issn.2095-610X.S20211234

Citation:

Lin ZHANG, Sha-sha DONG, Wan-xiong WANG, Hai-fang LI. Factors Influencing Potential Inappropriate Medication Use in Elderly Patients Based on Beers Criteria 2019 Edition[J]. Journal of Kunming Medical University, 2021, 42(12): 145-150. doi: 10.12259/j.issn.2095-610X.S20211234

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Factors Influencing Potential Inappropriate Medication Use in Elderly Patients Based on Beers Criteria 2019 Edition

doi: 10.12259/j.issn.2095-610X.S20211234

Dept. of Pharmacy，Kunming Second People’s Hospital，Kunming Yunnan 650021，China

Received Date: 2021-09-12
Available Online: 2021-11-17
Publish Date: 2021-12-15

Abstract

Abstract

Objective To investigate the incidence and influencing factors of potentially inappropriate medication （PIM） among hospitalized elderly patients, and provide reference for promoting rational drug use among elderly patients. Methods The incidence of PIM in elderly patients discharged from Kunming Second People’s Hospital from January to December 2019 was retrospectively investigated using Beers criteria （2019 edition） of American Geriatrics Society. The basic information and concomitant diseases of patients were collected, and the influencing factors of PIM were analyzed by Logistic regression method. Results According to the assessment of 2019 AGS Beers criteria, among 3577 elderly patients, the incidence of PIM was 58.51%, involving a total of 45 drugs and 3198 times. The top three drugs were gastrointestinal system drugs （48.23%）, diuretic drugs （39.47%） and central nervous system drugs （25.0%）. Logistic regression analysis showed that age ≥ 75 years, hospitalization ≥ 25 days, medication ≥ 10 kinds, heart failure, atrial fibrillation, cerebrovascular disease, gastrointestinal disease, insomnia, osteoporosis, hyperuricemia and pain were risk factors for PIM （P < 0.05）. Conclusion PIM was present in more than 50% of elderly inpatients in Kunming Second People’s Hospital. Advanced age, long hospital stay, heart failure, atrial fibrillation, cerebrovascular disease, gastrointestinal disease, insomnia, osteoporosis, hyperuricemia and pain were all independent risk factors for PIM.
- Elderly,
- Beers criteria（2019）,
- Inpatients,
- Potentially inappropriate medication

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