The Effectiveness of Endometrial Receptivity Test for Repeated Implantation Failure and Analysis of Clinical Factors Affecting Implantation Window

Yun BAI; Lei LI; Yuerong WU; Lanping ZHONG

doi:10.12259/j.issn.2095-610X.S20220501

Volume 43 Issue 5

May 2022

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Yun BAI, Lei LI, Yuerong WU, Lanping ZHONG. The Effectiveness of Endometrial Receptivity Test for Repeated Implantation Failure and Analysis of Clinical Factors Affecting Implantation Window[J]. Journal of Kunming Medical University, 2022, 43(5): 71-75. doi: 10.12259/j.issn.2095-610X.S20220501

Citation:

Yun BAI, Lei LI, Yuerong WU, Lanping ZHONG. The Effectiveness of Endometrial Receptivity Test for Repeated Implantation Failure and Analysis of Clinical Factors Affecting Implantation Window[J]. Journal of Kunming Medical University, 2022, 43(5): 71-75. doi: 10.12259/j.issn.2095-610X.S20220501

Citation:

Yun BAI, Lei LI, Yuerong WU, Lanping ZHONG. The Effectiveness of Endometrial Receptivity Test for Repeated Implantation Failure and Analysis of Clinical Factors Affecting Implantation Window[J]. Journal of Kunming Medical University, 2022, 43(5): 71-75. doi: 10.12259/j.issn.2095-610X.S20220501

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The Effectiveness of Endometrial Receptivity Test for Repeated Implantation Failure and Analysis of Clinical Factors Affecting Implantation Window

doi: 10.12259/j.issn.2095-610X.S20220501

Dept. of Reproductive Medicine，The 1st People’s Hospital of Yunnan & The Affiliated Hospital of Kunming University of Science and Technology， Kunming Yunnan 650032，China

Received Date: 2022-01-19
Available Online: 2022-05-12
Publish Date: 2022-05-27

Abstract

Abstract

Objective To investigate the efficacy of personalized transplantation of Endometrial Receptivity Test （ERT） in improving the clinical outcome of patients with repeated implantation failure, and to analyze the clinical factors affecting Endometrial Receptivity. Methods A retrospective cohort study was conducted on the clinical data of patients diagnosed with repeated transplantation failure in the Reproductive Medicine Department of the First People’s Hospital of Yunnan from December 2020 to November 2021. The patients were divided into two groups according to whether or not they had undergone endometrial receptivity testing and retransplanted embryos according to the test results. The clinical outcomes were compared between the two groups. The clinical factors affecting the endometrial receptivity were^[1] analyzed. Results The clinical pregnancy rate and embryo implantation rate in the receiving group were significantly higher than those in the non-receiving group （P < 0.05）. Multivariate regression analysis showed that polycystic ovary syndrome and the occurrence of follicular unruptured luteinization were the influencing factors of implantation window shift （P < 0.05）. Conclusion For patients with repeated implantation failure, transplantation can improve the outcome of assisted pregnancy according to ERT test results; Polycystic ovary syndrome and luteinization of unruptured follicles are risk factors for the implantation window displacement in patients with repeated implantation failure.
- Repeated implantation failure,
- Endometrial receptivity test,
- In vitro fertilization-embryo transfer

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References(13)

References

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