Clinical Distribution and Drug Resistance Analysis of <i>Acineto Bacterbaumannii</i> from 2014 to 2020

Jinyi GU; Deyao DENG; Wenli YUAN; Qiuping YANG; Jianmei SONG; Yanjun SHEN; Yuanyuan GUO; Hongyun XU

doi:10.12259/j.issn.2095-610X.S20220504

Volume 43 Issue 5

May 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(5): 83-87

Jinyi GU, Deyao DENG, Wenli YUAN, Qiuping YANG, Jianmei SONG, Yanjun SHEN, Yuanyuan GUO, Hongyun XU. Clinical Distribution and Drug Resistance Analysis of Acineto Bacterbaumannii from 2014 to 2020[J]. Journal of Kunming Medical University, 2022, 43(5): 83-87. doi: 10.12259/j.issn.2095-610X.S20220504

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Jinyi GU, Deyao DENG, Wenli YUAN, Qiuping YANG, Jianmei SONG, Yanjun SHEN, Yuanyuan GUO, Hongyun XU. Clinical Distribution and Drug Resistance Analysis of Acineto Bacterbaumannii from 2014 to 2020[J]. Journal of Kunming Medical University, 2022, 43(5): 83-87. doi: 10.12259/j.issn.2095-610X.S20220504

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Clinical Distribution and Drug Resistance Analysis of Acineto Bacterbaumannii from 2014 to 2020

doi: 10.12259/j.issn.2095-610X.S20220504

Dept. of Medical Laboratory，The Affiliated Hospital of Yunnan University/The 2nd People’s Hospital of Yunnan Province，Kunming Yunnan 650021，China

Received Date: 2022-02-01
Available Online: 2022-05-12
Publish Date: 2022-05-27

Abstract

Abstract

Objective To observe the clinical distribution and drug-resistance of A.baumannii, so as to provide the reference for the rational use of antibiotics in clinic. Methods Data of 2453 A.baumannii isolated from the clinical samples in a hospital from January 2014 to December 2020 were analyzed retrospectively. Results A total of 2453 strains of A.baumannii were mainly isolated from the patients in the Intensive Care Unit （35.2%） and surgery department （22.1%）. The ages of the patients with A.baumannii detected in the hospital were mainly over 60 years old （59.1%）. The detection rate of A.baumannii isolated from the males （8.64%） was significantly higher than that from the females （5.39%）（P < 0.01）. Meanwhile, the detection rate of multidrug-resistant A.baumannii isolated from the males （7.39%） was significantly higher than that from the females （3.58%）（P < 0.01）. In addition to Levofloxacin, the resistance rates to Piperacillin, Imipenem, Meropenem, Piperacillin/Tazobactam and Tetracycline were increasing year by year. The isolation rate of multidrug resistant A.baumannii was also increased in the observation period. Furthermore, the drug resistance rate of the imipenem-resistant A.baumannii to 12 kinds of antibacterial drugs, such as Piperacillin, was significantly higher than that of the imipenem-sensitive strains. Conclusion A.baumannii isolated are mainly from the intensive care unit and surgery department. The susceptibility of the male patients to A.baumannii is higher than that of the females. The drug resistance rate of A.baumannii and the isolation rate of multidrug resistant A.baumannii are on the rise and the detection rate of multidrug-resistant A.baumannii is increasing year by year. It is necessary to strengthen the monitoring of A.baumannii and use antimicrobial agents rationally.
- Acinetobacter baumannii,
- Drug resistance,
- Antibiotics,
- Male

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