Volume 44 Issue 1
Jan.  2023
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Citation: Yao HUANG, Xi LI, Bo YAN, Lei LEI, Zegang YIN, Jin FAN, Peng BAI. Correlation between Internal Carotid Artery Stenosis and Cognitive Impairment[J]. Journal of Kunming Medical University, 2023, 44(1): 70-75. doi: 10.12259/j.issn.2095-610X.S20230105
shu

Correlation between Internal Carotid Artery Stenosis and Cognitive Impairment

doi: 10.12259/j.issn.2095-610X.S20230105
  • 1.

    Dept. of Neurology，The General Hospital of the Western Theater Command，Chengdu Sichuan 610000

  • 2.

    Dept. of Cerebrovascular Disease，Guangyuan Central Hospital，Guangyuan Sichuan 628000

  • 3.

    Dept. of NeurosurgeryⅡ，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

  • Received Date: 2022-09-25
    Available Online: 2022-12-24
  • Publish Date: 2023-01-18
    Abstract
  •   Objective  To investigate the correlation of different degrees and sides of internal carotid artery stenosis with cognitive impairment.   Methods  From June 2017 to August 2018, patients for cerebrovascular examination with CTA or DSA were selected from the neurology department of a certain hospital. They were divided into the stenosis group and the control group according to the examination results. All the enrolled patients were examined with memory assessment scale+modified WCST. The assessment scores were recorded and the difference of scores among the patients in each group was statistically analyzed.   Results  65 cases were included in the study, which were divided into stenosis group （34 cases in total） and control group （31 cases in total） according to the examination results.The stenosis group was divided into mild stenosis group （15 cases in total） and moderate severe stenosis group （19 cases in total） according to the degree of stenosis. And the stenosis group was again divided into left stenosis group （24 cases in total） and right stenosis group （ 10 cases in total） according to the side. The memory and executive ability of the stenosis group and the control group were significantly impaired, the difference was statistically significant （P < 0.05）. The degree and side of stenosis had no correlation with memory and executive ability, and the difference was not statistically significant （P > 0.05）.   Conclusion  Internal carotid artery stenosis significantly affects cognitive function as indicated by memory and executive ability. However, the severity and side of stenosis are not related to cognitive function.
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