Volume 44 Issue 9
Sep.  2023
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Article Navigation >  Journal of Kunming Medical University  > 2023  >  44(9): 155-160
Chunmei MENG, Kefan YE, Yunyu HE, Dongyan REN, Xiaomei WU, Yifeng ZHANG. Evaluation of Therapeutic Effect of Transabdominal and Transvaginal Ultrasound on Cesarean Scar Pregnancy[J]. Journal of Kunming Medical University, 2023, 44(1): 65-69. doi: 10.12259/j.issn.2095-610X.S20230113
Citation: Shijie CAO, Hongwei AN. Mechanism and Progress of MSC Derived Extracellular Vesicles in the Treatment of Ischemic Stroke[J]. Journal of Kunming Medical University, 2023, 44(9): 155-160. doi: 10.12259/j.issn.2095-610X.S20230913
shu

Mechanism and Progress of MSC Derived Extracellular Vesicles in the Treatment of Ischemic Stroke

doi: 10.12259/j.issn.2095-610X.S20230913
  • 1.

    Guangxi University of Chinese Medicine，Nanning Guangxi 530001

  • 2.

    Liuzhou Traditional Chinese Medicine Hospital，Liuzhou Guangxi 545001，China

  • Received Date: 2023-05-09
    Available Online: 2023-09-23
  • Publish Date: 2023-09-30
    Abstract
  • Cerebral ischemic stoke is a disease in which oxidative stress, activation of inflammatory storms, interference, induction of apoptosis, and blood reperfusion aggravate the tissue and cell damage due to ischemia and hypoxia. Mesenchymal stem cells（MSCs） induce the angiogenesis and can be used to treat the ischemia-reperfusion injury, anti-apoptosis and anti-inflammatory. Preclinical studies have confirmed that targeted delivery of mesenchymal-derived exosomes to recipient cells exerts the effects of inducing angiogenesis, anti-apoptosis, and anti-inflammatory, while avoiding the shortcomings of mesenchymal stem cell therapy. The purpose of this study is to summarize the mechanism of exosomes derived from mesenchymal stem cells in the treatment of stroke so as to provide new opportunities for treating ischemic cerebrovascular disease clinically.
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    • References(31)
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