Interventional Treatment of Muscular Ventricular Septal Defect in Children

Wei HU; Jinnan LI; Wei YANG; Li SU; Zhuo YU; Zhisong CHEN

doi:10.12259/j.issn.2095-610X.S20240307

Volume 45 Issue 3

Mar. 2024

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Wei HU, Jinnan LI, Wei YANG, Li SU, Zhuo YU, Zhisong CHEN. Interventional Treatment of Muscular Ventricular Septal Defect in Children[J]. Journal of Kunming Medical University, 2024, 45(3): 48-53. doi: 10.12259/j.issn.2095-610X.S20240307

Citation:

Wei HU, Jinnan LI, Wei YANG, Li SU, Zhuo YU, Zhisong CHEN. Interventional Treatment of Muscular Ventricular Septal Defect in Children[J]. Journal of Kunming Medical University, 2024, 45(3): 48-53. doi: 10.12259/j.issn.2095-610X.S20240307

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Interventional Treatment of Muscular Ventricular Septal Defect in Children

doi: 10.12259/j.issn.2095-610X.S20240307

Wei HU¹,
Jinnan LI²,
Wei YANG³,
Li SU¹,
Zhuo YU¹,
Zhisong CHEN^{1
,
,}

1.
Dept. of Cardiology，The 1st Clinical College，Kunming Medical University，Kunming Yunnan 650032
2.
Dept. of Cardiology，Guang’an People’s Hospital，Guang’an Sichuan 638001
3.
Dept. of Anesthesiology，The 1st Clinical College，Kunming Medical University， Kunming Yunnan 650032，China

Received Date: 2023-09-23
Publish Date: 2024-03-25

Abstract

Abstract

Objects To explore the effectiveness and safety of using the Cardio-O-Fix Plug occluder in the treatment of muscular ventricular septal defect（mVSD） in children. Methods 14 patients with mVSD were taken to the cardiology department of First Affiliated Hospital of Kunming Medical University from July 2015 to June 2021 as research subjects. They were divided into two groups: 14 children who received Cardi-O-Fix Plug occluder as the experimental group, and 10 children who received Cardi-O-O-Fix mVSD occluder as the control group. Electrocardiogram and transthoracic echocardiography were used to evaluate the occlusive efficacy and incidence of complications 1 day after surgery and 1 month, 3 months, and 6 months of follow-up. Results Among the 24 pediatric patients, 22 cases were successfully occluded, and 2 cases were unsuccessful（1 in the experimental group and 1 in the control group）. The success rate of the experimental group was 92.8%（13/14）, while the success rate of the control group was 90.0%（9/10）. The average surgical duration of the experimental group was（71.93 ± 14.85） minutes, while the average surgical duration of the control group was（90.70 ± 19.78） minutes. There was a significant statistical difference between the two groups（P < 0.05）. Both the experimental group and the control group did not experience serious complications during surgery and follow-up. There was no significant difference in cardiac ultrasound indicators（including left ventricular ejection fraction, left ventricular end-diastolic diameter, and pulmonary artery pressure） between the two groups at different time points（ P > 0.05）. Conclusion Transcatheter closure of mVSD using Cardi-O-Fix Plug occluder in children is both safe and effective. The incidence of arrhythmia is low in the short, medium and long term.
- Ventricular septal defect,
- Muscule,
- Occluder,
- Domestic,
- Percutaneous intervention,
- Congenital heart disease,
- Children

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References(15)

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